TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Sinhgad College Of Pharmacy
Curated by ChEMBL
Sinhgad College Of Pharmacy
Curated by ChEMBL
Affinity DataKi: 0.0200nMAssay Description:Binding affinity to adrenergic alpha1A receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Displacement of [125]OXY from kappa opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of [125]OXY from kappa opioid receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Sinhgad College Of Pharmacy
Curated by ChEMBL
Sinhgad College Of Pharmacy
Curated by ChEMBL
Affinity DataKi: 1.92nMAssay Description:Binding affinity to 5HT2A (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Displacement of [125]OXY from kappa opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [125]OXY from kappa opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [125]OXY from mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [125]OXY from mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [125]OXY from mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [125]OXY from kappa opioid receptorMore data for this Ligand-Target Pair
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Sinhgad College Of Pharmacy
Curated by ChEMBL
Sinhgad College Of Pharmacy
Curated by ChEMBL
Affinity DataKi: 47nMAssay Description:Binding affinity to adrenergic alpha1B receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of [125]OXY from kappa opioid receptorMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Inhibition of MK499 binding to human ERGMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Displacement of [125]OXY from kappa opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Displacement of [125]OXY from kappa opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Displacement of [125]OXY from kappa opioid receptorMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 80nMAssay Description:Inhibition of MK499 binding to human ERGMore data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Displacement of [125]OXY from kappa opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Displacement of [125]OXY from kappa opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Displacement of [125]OXY from kappa opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Displacement of [125]OXY from mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Displacement of [125]OXY from mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Displacement of [125]OXY from kappa opioid receptorMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 220nMAssay Description:In vitro inhibitory activity against human leukocyte elastase (HLE)More data for this Ligand-Target Pair
Affinity DataKi: 220nMAssay Description:Displacement of [125]OXY from mu opioid receptorMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 250nMAssay Description:In vitro inhibitory activity against human leukocyte elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:Displacement of [125]OXY from kappa opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 280nMAssay Description:Displacement of [125]OXY from mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 290nMAssay Description:Displacement of [125]OXY from kappa opioid receptorMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 290nMAssay Description:Inhibition of MK499 binding to human ERGMore data for this Ligand-Target Pair
Affinity DataKi: 310nMAssay Description:Displacement of [125]OXY from mu opioid receptorMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 440nMAssay Description:Inhibition of MK499 binding to human ERGMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 500nMAssay Description:Second order rate constant for the in vitro inhibitory activity against human leukocyte elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 520nMAssay Description:Displacement of [125]OXY from mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 520nMAssay Description:Displacement of [125]OXY from mu opioid receptorMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 720nMAssay Description:Inhibition of MK499 binding to human ERGMore data for this Ligand-Target Pair
Affinity DataKi: 740nMAssay Description:Displacement of [125]OXY from kappa opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [125]OXY from mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [125]OXY from mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.09E+3nMAssay Description:Displacement of [125]OXY from mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.17E+3nMAssay Description:Displacement of [125]OXY from delta opioid receptorMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.30E+3nMAssay Description:Tested in vitro for its inhibitory effect against Elastase using Suc-Ala--Ala-Pro-Ala-pNA as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1.38E+3nMAssay Description:Displacement of [125]OXY from delta opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.41E+3nMAssay Description:Displacement of [125]OXY from delta opioid receptorMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.50E+3nMAssay Description:Tested in vitro for its inhibitory effect against Elastase using Suc-Ala--Ala-Pro-Ala-pNA as substrateMore data for this Ligand-Target Pair