Compile Data Set for Download or QSAR
maximum 50k data
Found 478 with Last Name = 'shenderovich' and Initial = 'm'
TargetDelta-type opioid receptor(MOUSE)
TBA

Curated by ChEMBL
LigandPNGBDBM50060080(2-({2-[(R)-2-Amino-3-(4-hydroxy-2,6-dimethyl-pheny...)
Affinity DataKi:  191nMAssay Description:The compound was evaluated for the binding affinity towards delta-opioid receptor by displacement of [3H]p-CI-DPDPE radioligand from mouse vas defere...More data for this Ligand-Target Pair
In DepthDetails Article
TargetMu-type opioid receptor(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50060080(2-({2-[(R)-2-Amino-3-(4-hydroxy-2,6-dimethyl-pheny...)
Affinity DataKi:  2.84E+4nMAssay Description:The compound was evaluated for the binding affinity towards mu-opioid receptor by displacement of [3H]DAMGO radioligand from guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails Article
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474951(US10849901, Compound 1)
Affinity DataIC50:  0.25nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Myrexis

Curated by ChEMBL
LigandPNGBDBM50347432(CHEMBL1801863)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of nicotinamide phosphoribosyltransferase-catalyzed conversion of nicotinamide to nicotinamide mononucleotideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Myrexis

Curated by ChEMBL
LigandPNGBDBM50117198(4-{[7-Chloro-3-methyl-2-(4-methyl-piperazin-1-ylme...)
Affinity DataIC50:  0.310nMAssay Description:Inhibition of nicotinamide phosphoribosyltransferase-catalyzed conversion of nicotinamide to nicotinamide mononucleotideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50039026(4-((R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl...)
Affinity DataIC50:  0.310nMAssay Description:Binding affinity was measured against Opioid receptor delta 1 using [3H]-p-Cl-DPDPE as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474952(US10849901, Compound 2)
Affinity DataIC50:  0.330nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Myrexis

Curated by ChEMBL
LigandPNGBDBM50347433(CHEMBL1801864)
Affinity DataIC50:  0.450nMAssay Description:Inhibition of nicotinamide phosphoribosyltransferase-catalyzed conversion of nicotinamide to nicotinamide mononucleotideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474954(US10849901, Compound 4)
Affinity DataIC50:  0.460nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474953(US10849901, Compound 3)
Affinity DataIC50:  0.5nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474954(US10849901, Compound 4)
Affinity DataIC50:  0.520nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Myrexis

Curated by ChEMBL
LigandPNGBDBM50347427(CHEMBL1801934)
Affinity DataIC50:  0.550nMAssay Description:Inhibition of nicotinamide phosphoribosyltransferase-catalyzed conversion of nicotinamide to nicotinamide mononucleotideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM475063(US10849901, Compound 113)
Affinity DataIC50:  0.560nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474955(US10849901, Compound 5)
Affinity DataIC50:  0.580nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDelta-type opioid receptor(MOUSE)
TBA

Curated by ChEMBL
LigandPNGBDBM50038424((S)-3-[(S)-2-((R)-2-Amino-propionylamino)-3-phenyl...)
Affinity DataIC50:  0.600nMAssay Description:Binding affinity opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
TBA

Curated by ChEMBL
LigandPNGBDBM50038424((S)-3-[(S)-2-((R)-2-Amino-propionylamino)-3-phenyl...)
Affinity DataIC50:  0.600nMAssay Description:Binding affinity opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474957(US10849901, Compound 7)
Affinity DataIC50:  0.660nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474956(US10849901, Compound 6)
Affinity DataIC50:  0.660nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474958(US10849901, Compound 8)
Affinity DataIC50:  0.670nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Myrexis

Curated by ChEMBL
LigandPNGBDBM50347431(CHEMBL1801862)
Affinity DataIC50:  0.790nMAssay Description:Inhibition of nicotinamide phosphoribosyltransferase-catalyzed conversion of nicotinamide to nicotinamide mononucleotideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474959(US10849901, Compound 9)
Affinity DataIC50:  0.840nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474960(US10849901, Compound 10)
Affinity DataIC50:  0.880nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474962(US10849901, Compound 12)
Affinity DataIC50:  0.960nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474961(US10849901, Compound 11)
Affinity DataIC50:  0.960nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474963(US10849901, Compound 13)
Affinity DataIC50:  0.980nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Myrexis

Curated by ChEMBL
LigandPNGBDBM50386830(CHEMBL2047958)
Affinity DataIC50:  1nMAssay Description:Inhibition of Mps1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Myrexis

Curated by ChEMBL
LigandPNGBDBM50386829(CHEMBL2047956)
Affinity DataIC50:  1nMAssay Description:Inhibition of Mps1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474964(US10849901, Compound 14)
Affinity DataIC50:  1nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Myrexis

Curated by ChEMBL
LigandPNGBDBM50386825(CHEMBL2047952)
Affinity DataIC50:  1nMAssay Description:Inhibition of Mps1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474966(US10849901, Compound 16)
Affinity DataIC50:  1nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Myrexis

Curated by ChEMBL
LigandPNGBDBM50386824(CHEMBL2047951)
Affinity DataIC50:  1nMAssay Description:Inhibition of Mps1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50039029((+)-4-((alpha R)-((2S,5R)-4-allyl-2,5-dimethylpipe...)
Affinity DataIC50:  1.06nMAssay Description:Binding affinity was measured against Opioid receptor delta 1 using [3H]-p-Cl-DPDPE as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM33301(US10849901, Compound 115 | rhodanine, 1-2)
Affinity DataIC50:  1.10nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474956(US10849901, Compound 6)
Affinity DataIC50:  1.10nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474965(US10849901, Compound 15)
Affinity DataIC50:  1.10nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM475064(US10849901, Compound 114)
Affinity DataIC50:  1.10nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474968(US10849901, Compound 18)
Affinity DataIC50:  1.10nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474969(US10849901, Compound 19)
Affinity DataIC50:  1.10nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474970(US10849901, Compound 20)
Affinity DataIC50:  1.10nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474967(US10849901, Compound 17)
Affinity DataIC50:  1.10nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM475092(US10849901, Compound 142)
Affinity DataIC50:  1.20nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474971(US10849901, Compound 21)
Affinity DataIC50:  1.20nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474972(US10849901, Compound 22 | US10849901, Compound 27)
Affinity DataIC50:  1.20nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474973(US10849901, Compound 23)
Affinity DataIC50:  1.20nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Myrexis

Curated by ChEMBL
LigandPNGBDBM50347394(CHEMBL1801566)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of nicotinamide phosphoribosyltransferase-catalyzed conversion of nicotinamide to nicotinamide mononucleotideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Myrexis

Curated by ChEMBL
LigandPNGBDBM50347407(CHEMBL1801561)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of nicotinamide phosphoribosyltransferase-catalyzed conversion of nicotinamide to nicotinamide mononucleotideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474974(US10849901, Compound 24)
Affinity DataIC50:  1.30nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Myrexis

Curated by ChEMBL
LigandPNGBDBM50347415(CHEMBL1801552)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of nicotinamide phosphoribosyltransferase-catalyzed conversion of nicotinamide to nicotinamide mononucleotideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM50168142(CHEMBL3716578 | US10849901, Compound 38 | US109530...)
Affinity DataIC50:  1.40nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474978(US10849901, Compound 28)
Affinity DataIC50:  1.40nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Displayed 1 to 50 (of 478 total ) | Next | Last >>
Jump to: