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Found 230 with Last Name = 'singh' and Initial = 'sm'
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034137(CHEMBL275153 | N-Pentyl-N-((4aR,6aS,7S,11aR)-1,4a,...)
Affinity DataIC50:  0.910nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034151(CHEMBL280015 | Pentanoic acid pentyl-((4aR,6aS,7S,...)
Affinity DataIC50:  1.80nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034161(CHEMBL17245 | N-(4-Methoxy-phenyl)-N-((4aR,6aS,7S,...)
Affinity DataIC50:  2.10nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034134(CHEMBL17222 | N-(3-Methyl-butyl)-N-((4aR,6aS,7S,11...)
Affinity DataIC50:  2.20nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034142(CHEMBL16863 | N-(3,3-Dimethyl-butyl)-N-((4aR,6aS,7...)
Affinity DataIC50:  2.40nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034135(5-Bromo-pentanoic acid pentyl-((4aR,6aS,7S,11aR)-1...)
Affinity DataIC50:  2.40nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Mus musculus)
Endorecherche

US Patent
LigandPNGBDBM148342(US9682960, EM-9028)
Affinity DataIC50:  2.60nMpH: 7.4 T: 2°CAssay Description:Androgen binding is measured using the hydroxylapatite (HAP) assay. In brief, the radioactive steroid [3H]R1881 solubilized in ethanol is diluted wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Mus musculus)
Endorecherche

US Patent
LigandPNGBDBM144439(US9682960, EM-9025)
Affinity DataIC50:  2.70nMpH: 7.4 T: 2°CAssay Description:Androgen binding is measured using the hydroxylapatite (HAP) assay. In brief, the radioactive steroid [3H]R1881 solubilized in ethanol is diluted wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034157(CHEMBL276320 | N-Phenyl-N-((4aR,6aS,7S,11aR)-1,4a,...)
Affinity DataIC50:  2.90nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034143(CHEMBL277053 | N-Butyl-N-((4aR,6aS,7S,11aR)-1,4a,6...)
Affinity DataIC50:  3.10nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034141(CHEMBL16784 | N-Pentyl-N-((4aR,6aS,7S,11aR)-1,4a,6...)
Affinity DataIC50:  3.20nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034159(CHEMBL278490 | N-Pentyl-N-((4aR,6aS,7S,11aR)-1,4a,...)
Affinity DataIC50:  3.30nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Mus musculus)
Endorecherche

US Patent
LigandPNGBDBM143739(US9682960, EM-8929 | US9682960, EM-9043)
Affinity DataIC50:  3.40nMpH: 7.4 T: 2°CAssay Description:Androgen binding is measured using the hydroxylapatite (HAP) assay. In brief, the radioactive steroid [3H]R1881 solubilized in ethanol is diluted wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034157(CHEMBL276320 | N-Phenyl-N-((4aR,6aS,7S,11aR)-1,4a,...)
Affinity DataIC50:  3.80nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type 2 in SW-13-transfected cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Mus musculus)
Endorecherche

US Patent
LigandPNGBDBM143735(US9682960, EM-8900)
Affinity DataIC50:  3.80nMpH: 7.4 T: 2°CAssay Description:Androgen binding is measured using the hydroxylapatite (HAP) assay. In brief, the radioactive steroid [3H]R1881 solubilized in ethanol is diluted wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034147((4aR,6aS,7S,11aR)-1,4a,6a-Trimethyl-2-oxo-hexadeca...)
Affinity DataIC50:  4.10nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Mus musculus)
Endorecherche

US Patent
LigandPNGBDBM144442(US9682960, EM-9039)
Affinity DataIC50:  4.30nMpH: 7.4 T: 2°CAssay Description:Androgen binding is measured using the hydroxylapatite (HAP) assay. In brief, the radioactive steroid [3H]R1881 solubilized in ethanol is diluted wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)
Affinity DataIC50:  4.5nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type 2 in SW-13-transfected cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034130(CHEMBL17194 | N-Pentyl-N-((4aR,6aS,7S,11aR)-1,4a,6...)
Affinity DataIC50:  4.60nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Mus musculus)
Endorecherche

US Patent
LigandPNGBDBM148341(US9682960, EM-9021)
Affinity DataIC50:  5nMpH: 7.4 T: 2°CAssay Description:Androgen binding is measured using the hydroxylapatite (HAP) assay. In brief, the radioactive steroid [3H]R1881 solubilized in ethanol is diluted wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034132(CHEMBL274276 | N-Propyl-N-((4aR,6aS,7S,11aR)-1,4a,...)
Affinity DataIC50:  5.10nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Mus musculus)
Endorecherche

US Patent
LigandPNGBDBM146820(US9682960, EM-9198)
Affinity DataIC50:  5.30nMpH: 7.4 T: 2°CAssay Description:Androgen binding is measured using the hydroxylapatite (HAP) assay. In brief, the radioactive steroid [3H]R1881 solubilized in ethanol is diluted wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034150(CHEMBL16700 | N-(4-Methoxy-phenyl)-N-((4aR,6aS,7S,...)
Affinity DataIC50:  5.40nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034140(CHEMBL276527 | N-Benzyl-N-((4aR,6aS,7S,11aR)-1,4a,...)
Affinity DataIC50:  5.60nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Mus musculus)
Endorecherche

US Patent
LigandPNGBDBM143701(US9682960, EM-7365)
Affinity DataIC50:  6nMpH: 7.4 T: 2°CAssay Description:Androgen binding is measured using the hydroxylapatite (HAP) assay. In brief, the radioactive steroid [3H]R1881 solubilized in ethanol is diluted wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Mus musculus)
Endorecherche

US Patent
LigandPNGBDBM144438(US9682960, EM-9011)
Affinity DataIC50:  6.60nMpH: 7.4 T: 2°CAssay Description:Androgen binding is measured using the hydroxylapatite (HAP) assay. In brief, the radioactive steroid [3H]R1881 solubilized in ethanol is diluted wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Mus musculus)
Endorecherche

US Patent
LigandPNGBDBM144449(US9682960, EM-9049)
Affinity DataIC50:  6.80nMpH: 7.4 T: 2°CAssay Description:Androgen binding is measured using the hydroxylapatite (HAP) assay. In brief, the radioactive steroid [3H]R1881 solubilized in ethanol is diluted wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Mus musculus)
Endorecherche

US Patent
LigandPNGBDBM146850(US9682960, EM-9204)
Affinity DataIC50:  7nMpH: 7.4 T: 2°CAssay Description:Androgen binding is measured using the hydroxylapatite (HAP) assay. In brief, the radioactive steroid [3H]R1881 solubilized in ethanol is diluted wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Mus musculus)
Endorecherche

US Patent
LigandPNGBDBM143706(US9682960, EM-8360)
Affinity DataIC50:  7.10nMpH: 7.4 T: 2°CAssay Description:Androgen binding is measured using the hydroxylapatite (HAP) assay. In brief, the radioactive steroid [3H]R1881 solubilized in ethanol is diluted wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034139(CHEMBL16690 | N-Isobutyl-N-((4aR,6aS,7S,11aR)-1,4a...)
Affinity DataIC50:  7.30nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034154(CHEMBL17506 | N-Hexyl-N-((4aR,6aS,7S,11aR)-1,4a,6a...)
Affinity DataIC50:  7.30nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034147((4aR,6aS,7S,11aR)-1,4a,6a-Trimethyl-2-oxo-hexadeca...)
Affinity DataIC50:  7.5nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type 2 in SW-13-transfected cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)
Affinity DataIC50:  8.5nMAssay Description:In vitro inhibition of human Steroid 5-alpha-reductase type 2 in transfected SW-13 cells using [3H]- delta4-Androstenedione as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAndrogen receptor(Mus musculus)
Endorecherche

US Patent
LigandPNGBDBM144441(US9682960, EM-9037)
Affinity DataIC50:  8.70nMpH: 7.4 T: 2°CAssay Description:Androgen binding is measured using the hydroxylapatite (HAP) assay. In brief, the radioactive steroid [3H]R1881 solubilized in ethanol is diluted wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Mus musculus)
Endorecherche

US Patent
LigandPNGBDBM145918(US9682960, EM-9120)
Affinity DataIC50:  9.20nMpH: 7.4 T: 2°CAssay Description:Androgen binding is measured using the hydroxylapatite (HAP) assay. In brief, the radioactive steroid [3H]R1881 solubilized in ethanol is diluted wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Mus musculus)
Endorecherche

US Patent
LigandPNGBDBM143705(US9682960, EM-7148)
Affinity DataIC50:  9.20nMpH: 7.4 T: 2°CAssay Description:Androgen binding is measured using the hydroxylapatite (HAP) assay. In brief, the radioactive steroid [3H]R1881 solubilized in ethanol is diluted wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Mus musculus)
Endorecherche

US Patent
LigandPNGBDBM143710(US9682960, EM-9156 | US9682960, EM-9288)
Affinity DataIC50:  9.20nMpH: 7.4 T: 2°CAssay Description:Androgen binding is measured using the hydroxylapatite (HAP) assay. In brief, the radioactive steroid [3H]R1881 solubilized in ethanol is diluted wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Mus musculus)
Endorecherche

US Patent
LigandPNGBDBM143702(US9682960, EM-7105)
Affinity DataIC50:  9.40nMpH: 7.4 T: 2°CAssay Description:Androgen binding is measured using the hydroxylapatite (HAP) assay. In brief, the radioactive steroid [3H]R1881 solubilized in ethanol is diluted wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034153(CHEMBL17268 | N-Isopropyl-N-((4aR,6aS,7S,11aR)-1,4...)
Affinity DataIC50:  9.5nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034133(CHEMBL17206 | N-Heptyl-N-((4aR,6aS,7S,11aR)-1,4a,6...)
Affinity DataIC50:  9.60nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Mus musculus)
Endorecherche

US Patent
LigandPNGBDBM148337(US9682960, EM-8990)
Affinity DataIC50:  9.70nMpH: 7.4 T: 2°CAssay Description:Androgen binding is measured using the hydroxylapatite (HAP) assay. In brief, the radioactive steroid [3H]R1881 solubilized in ethanol is diluted wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Mus musculus)
Endorecherche

US Patent
LigandPNGBDBM146849(US9682960, EM-9201)
Affinity DataIC50:  9.70nMpH: 7.4 T: 2°CAssay Description:Androgen binding is measured using the hydroxylapatite (HAP) assay. In brief, the radioactive steroid [3H]R1881 solubilized in ethanol is diluted wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Mus musculus)
Endorecherche

US Patent
LigandPNGBDBM148339(US9682960, EM-9010)
Affinity DataIC50:  10nMpH: 7.4 T: 2°CAssay Description:Androgen binding is measured using the hydroxylapatite (HAP) assay. In brief, the radioactive steroid [3H]R1881 solubilized in ethanol is diluted wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034144(CHEMBL16533 | N-(1-Ethyl-propyl)-N-((4aR,6aS,7S,11...)
Affinity DataIC50:  11nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034145(CHEMBL276355 | N-Cyclopropyl-N-((4aR,6aS,7S,11aR)-...)
Affinity DataIC50:  11nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034162(CHEMBL266519 | N-Phenyl-N-((4aR,6aS,7S,11aR)-1,4a,...)
Affinity DataIC50:  11nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Mus musculus)
Endorecherche

US Patent
LigandPNGBDBM146873(US9682960, EM-9221)
Affinity DataIC50:  11nMpH: 7.4 T: 2°CAssay Description:Androgen binding is measured using the hydroxylapatite (HAP) assay. In brief, the radioactive steroid [3H]R1881 solubilized in ethanol is diluted wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Mus musculus)
Endorecherche

US Patent
LigandPNGBDBM144727(US9682960, EM-9055)
Affinity DataIC50:  11nMpH: 7.4 T: 2°CAssay Description:Androgen binding is measured using the hydroxylapatite (HAP) assay. In brief, the radioactive steroid [3H]R1881 solubilized in ethanol is diluted wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Mus musculus)
Endorecherche

US Patent
LigandPNGBDBM144728(US9682960, EM-9066)
Affinity DataIC50:  11nMpH: 7.4 T: 2°CAssay Description:Androgen binding is measured using the hydroxylapatite (HAP) assay. In brief, the radioactive steroid [3H]R1881 solubilized in ethanol is diluted wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Mus musculus)
Endorecherche

US Patent
LigandPNGBDBM145870(US9682960, EM-9092)
Affinity DataIC50:  11nMpH: 7.4 T: 2°CAssay Description:Androgen binding is measured using the hydroxylapatite (HAP) assay. In brief, the radioactive steroid [3H]R1881 solubilized in ethanol is diluted wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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