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Found 158 with Last Name = 'skiles' and Initial = 'jw'
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020771(CHEMBL160361 | [(3-Mercapto-2-methyl-propionyl)-p-...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50015471(1-[2-(1-Carboxy-3-phenyl-propylamino)-6-(4-chloro-...)
Affinity DataIC50:  6.5nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50015473(2-[1-(Carboxymethyl-indan-2-yl-carbamoyl)-5-(4-chl...)
Affinity DataIC50:  7nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50367217(CHEMBL1907938)
Affinity DataIC50:  16nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)
Affinity DataIC50:  17nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020794(CHEMBL348040 | [Cyclobutyl-(3-mercapto-2-methyl-pr...)
Affinity DataIC50:  18nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020766((R+S)-[Cyclopentyl-(3-mercapto-2-methyl-propionyl)...)
Affinity DataIC50:  18nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020761(CHEMBL346255 | [(3-Mercapto-2-methyl-propionyl)-m-...)
Affinity DataIC50:  19nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020791(CHEMBL346561 | [(3-Acetylsulfanyl-2-methyl-propion...)
Affinity DataIC50:  20nMpH: 8.3Assay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020791(CHEMBL346561 | [(3-Acetylsulfanyl-2-methyl-propion...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)
Affinity DataIC50:  23nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)
Affinity DataIC50:  23nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020793(CHEMBL23727 | [(4-Fluoro-phenyl)-(3-mercapto-2-met...)
Affinity DataIC50:  23nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021340(CHEMBL166743 | [(2-Mercapto-propionyl)-p-tolyl-ami...)
Affinity DataIC50:  26nMAssay Description:Inhibition of the activity of rabbit lung Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005159(4-(4-Chloro-benzenesulfonylaminocarbonyl)-N-(2-met...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibitory activity against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020779(CHEMBL158962 | [Cyclopropyl-(3-mercapto-2-methyl-p...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020808(CHEMBL1788147 | CHEMBL278348 | [Indan-2-yl-(3-merc...)
Affinity DataIC50:  31nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020798(CHEMBL1788148 | CHEMBL23841 | [Cycloheptyl-(3-merc...)
Affinity DataIC50:  31nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020769(CHEMBL345858 | [Bicyclo[2.2.1]hept-2-yl-(3-mercapt...)
Affinity DataIC50:  32nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020801(CHEMBL23641 | [Indan-5-yl-(3-mercapto-2-methyl-pro...)
Affinity DataIC50:  33nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020768(CHEMBL1788152 | CHEMBL23518 | [Cyclohexyl-(3-merca...)
Affinity DataIC50:  35nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005147((S)-1-{(S)-2-[4-(4-Bromo-benzenesulfonylaminocarbo...)
Affinity DataIC50:  38nMAssay Description:In vitro inhibitory activity against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50015477(2-[1-(Carboxymethyl-indan-2-yl-carbamoyl)-5-(4-chl...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020763(CHEMBL422013 | [(3-Acetylsulfanyl-2-methyl-propion...)
Affinity DataIC50:  44nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020803(CHEMBL350484 | [(3,5-Dimethyl-phenyl)-(3-mercapto-...)
Affinity DataIC50:  44nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020786(CHEMBL406430 | [(3-Acetylsulfanyl-2-methyl-propion...)
Affinity DataIC50:  45nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020792(CHEMBL347259 | [(3-Acetylsulfanyl-2-methyl-propion...)
Affinity DataIC50:  48nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020778(CHEMBL159075 | [(3-Acetylsulfanyl-2-methyl-propion...)
Affinity DataIC50:  51nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005166(4-(4-Chloro-benzenesulfonylaminocarbonyl)-N-(2-met...)
Affinity DataIC50:  52nMAssay Description:In vitro inhibitory activity against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020810(CHEMBL346588 | [(3-Mercapto-2-methyl-propionyl)-(3...)
Affinity DataIC50:  55nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020780(CHEMBL422535 | [(3-Mercapto-2-methyl-propionyl)-th...)
Affinity DataIC50:  55nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021332(CHEMBL165952 | [Cyclopentyl-(2-mercapto-propionyl)...)
Affinity DataIC50:  57nMAssay Description:Inhibition of the activity of rabbit lung Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50004182(2-Acetylamino-6-(4-{2-[(2-benzyloxycarbonylamino-3...)
Affinity DataIC50:  57nMpH: 7.5Assay Description:Inhibitory activity against human leukocyte elastase (HLE) at pH 7.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005176(4-{{2-[4-(4-Chloro-benzenesulfonylaminocarbonyl)-b...)
Affinity DataIC50:  57nMAssay Description:In vitro inhibitory activity against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020807(CHEMBL350258 | [(3-Acetylsulfanyl-2-methyl-propion...)
Affinity DataIC50:  60nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005174(CHEMBL435649 | N-(1-{Bicyclo[2.2.1]hept-2-yl-[(3,3...)
Affinity DataIC50:  61nMAssay Description:In vitro inhibitory activity against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020783(CHEMBL347447 | [(3-Acetylsulfanyl-2-methyl-propion...)
Affinity DataIC50:  64nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005154(CHEMBL423067 | {2-Methyl-1-[2-(3,3,3-trifluoro-1-i...)
Affinity DataIC50:  65nMAssay Description:In vitro inhibitory activity against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005156(4-(4-Chloro-benzenesulfonylaminocarbonyl)-N-(1-{cy...)
Affinity DataIC50:  67nMAssay Description:In vitro inhibitory activity against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50004192(CHEMBL344981 | [2-(4-{2-[(2-Benzyloxycarbonylamino...)
Affinity DataIC50:  69nMpH: 7.5Assay Description:Inhibitory activity against human leukocyte elastase (HLE) at pH 7.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020784(CHEMBL346495 | [Isopropyl-(3-mercapto-2-methyl-pro...)
Affinity DataIC50:  72nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005178(4-(4-Chloro-benzenesulfonylaminocarbonyl)-N-(2-met...)
Affinity DataIC50:  73nMAssay Description:In vitro inhibitory activity against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005152(CHEMBL160365 | {2-Methyl-1-[3-(3,3,3-trifluoro-1-i...)
Affinity DataIC50:  73nMAssay Description:In vitro inhibitory activity against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005152(CHEMBL160365 | {2-Methyl-1-[3-(3,3,3-trifluoro-1-i...)
Affinity DataIC50:  73nMAssay Description:In vitro inhibitory activity against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020756(CHEMBL348043 | [(3-Acetylsulfanyl-2-methyl-propion...)
Affinity DataIC50:  75nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020774(CHEMBL160689 | [Ethyl-(3-mercapto-2-methyl-propion...)
Affinity DataIC50:  75nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020787(CHEMBL345619 | [(3-Acetylsulfanyl-2-methyl-propion...)
Affinity DataIC50:  75nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020760(2-[Cyclopropyl-(3-mercapto-2-methyl-propionyl)-ami...)
Affinity DataIC50:  79nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50020799(CHEMBL160770 | [(3-Acetylsulfanyl-2-methyl-propion...)
Affinity DataIC50:  82nMAssay Description:In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50004184(4-(4-Chloro-benzenesulfonylaminocarbonyl)-N-((S)-1...)
Affinity DataIC50:  84nMAssay Description:In vitro inhibitory activity against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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