Compile Data Set for Download or QSAR
maximum 50k data
Found 2944 with Last Name = 'son' and Initial = 'jb'
TargetDihydrofolate reductase(Escherichia coli)
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataKi:  0.00100nMAssay Description:Inhibition of recombinant Escherichia coli DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataKi:  0.00300nMAssay Description:Inhibition of recombinant human DHFR assessed as reduction in NADPH oxidation using dihydrofolate as substrate by fluorescence spectrophotometric ana...More data for this Ligand-Target Pair
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571836((Z)-3-((6-((4-Carbamimidoyl-2-fluorophenoxy)carbon...)
Affinity DataKi:  0.160nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Escherichia coli)
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)
Affinity DataKi:  0.220nMAssay Description:Inhibition of recombinant Escherichia coli DHFR expressed in Escherichia coli BL21(DE3) cells assessed as reduction in NADPH oxidation using dihydrof...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571793((3-((5-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)...)
Affinity DataKi:  0.520nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571830(3-((6-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)b...)
Affinity DataKi:  0.550nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571817(3-((6-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)b...)
Affinity DataKi:  0.570nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571815(4-((6-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)b...)
Affinity DataKi:  0.570nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571802(4-((5-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)t...)
Affinity DataKi:  0.570nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571797((3-((5-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)...)
Affinity DataKi:  0.570nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571814(3-((6-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)b...)
Affinity DataKi:  0.590nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571772(1-(5-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)th...)
Affinity DataKi:  0.600nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571760(3-((5-((4-carbamimidoyl-2-fluorophenoxy)carbonyl)t...)
Affinity DataKi:  0.680nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571843(3-((6-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)b...)
Affinity DataKi:  0.700nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571841(3-((6-((4-Carbamimidoylphenoxy)carbonyl)benzo[d]th...)
Affinity DataKi:  0.890nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Escherichia coli)
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM210930(UCP1173)
Affinity DataKi:  0.910nMAssay Description:Inhibition of recombinant Escherichia coli DHFR expressed in Escherichia coli BL21(DE3) cells assessed as reduction in NADPH oxidation using dihydrof...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571766(4-Carbamimidoyl-2-fluorophenyl 2-(4-(methoxycarbon...)
Affinity DataKi:  0.920nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Escherichia coli)
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM50190621(CHEMBL3827532 | US10870625, Compound 15)
Affinity DataKi:  0.980nMAssay Description:Inhibition of recombinant Escherichia coli DHFR expressed in Escherichia coli BL21(DE3) cells assessed as reduction in NADPH oxidation using dihydrof...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571783((1-(5-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)t...)
Affinity DataKi:  1nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
University Of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50264380(CHEMBL4078717)
Affinity DataKi: <1nMAssay Description:Displacement of [3H]UR-3189 from integrin alpha2b beta3 receptor in resting human plateletMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Staphylococcus aureus)
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataKi:  1nMAssay Description:Inhibition of Staphylococcus aureus DHFRMore data for this Ligand-Target Pair
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571839(4-Carbamimidoyl-2-fluorophenyl 2-((4-methoxy-4-oxo...)
Affinity DataKi:  1.10nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM50223637(Alphacemethadone | Alphacetylmethadol)
Affinity DataKi:  1.20nMAssay Description:Inhibition of [3H]- naloxone binding to Opioid receptors in rat brain membrane in the absence of NaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571840(4-Carbamimidoyl-2-fluorophenyl 2-((3-methoxy-3-oxo...)
Affinity DataKi:  1.30nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM210930(UCP1173)
Affinity DataKi:  1.30nMAssay Description:Inhibition of recombinant Staphylococcus aureus DHFR expressed in Escherichia coli BL21(DE3) cells assessed as reduction in NADPH oxidation using dih...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571789(3-(1-(5-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl...)
Affinity DataKi:  1.5nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM210931(UCP1175)
Affinity DataKi:  1.60nMAssay Description:Inhibition of recombinant Staphylococcus aureus DHFR expressed in Escherichia coli BL21(DE3) cells assessed as reduction in NADPH oxidation using dih...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571787(4-(1-(5-((4-carbamimidoyl-2-fluorophenoxy)carbonyl...)
Affinity DataKi:  1.60nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571785(3-(1-(5-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl...)
Affinity DataKi:  1.70nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Escherichia coli)
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM210929(UCP1172)
Affinity DataKi:  1.80nMAssay Description:Inhibition of recombinant Escherichia coli DHFR expressed in Escherichia coli BL21(DE3) cells assessed as reduction in NADPH oxidation using dihydrof...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571781(4-Carbamimidoyl-2-fluorophenyl 2-(4-((4-methoxy-4-...)
Affinity DataKi:  1.80nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571773(4-Carbamimidoyl-2-fluorophenyl 2-(4-((2-methoxy-2-...)
Affinity DataKi:  1.80nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571824(4-Carbamimidoyl-2-fluorophenyl 2-(4-benzoamidopipe...)
Affinity DataKi:  1.90nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Escherichia coli)
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM50190622(CHEMBL3827326)
Affinity DataKi:  1.90nMAssay Description:Inhibition of recombinant Escherichia coli DHFR expressed in Escherichia coli BL21(DE3) cells assessed as reduction in NADPH oxidation using dihydrof...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50223633(Levomethadone)
Affinity DataKi:  2nMAssay Description:Inhibition of [3H]- naloxone binding to Opioid receptors in rat brain membrane in the absence of NaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM50190619(CHEMBL3827086 | US10870625, Compound 14)
Affinity DataKi:  2.10nMAssay Description:Inhibition of recombinant Escherichia coli DHFR expressed in Escherichia coli BL21(DE3) cells assessed as reduction in NADPH oxidation using dihydrof...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Staphylococcus aureus)
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM210929(UCP1172)
Affinity DataKi:  2.10nMAssay Description:Inhibition of recombinant Staphylococcus aureus DHFR expressed in Escherichia coli BL21(DE3) cells assessed as reduction in NADPH oxidation using dih...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571828(4-Carbamimidoyl-2-fluorophenyl 2-(ethyl(3-methoxy-...)
Affinity DataKi:  2.20nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571777(4-Carbamimidoyl-2-fluorophenyl 2-(4-((3-methoxy-2,...)
Affinity DataKi:  2.5nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571806(3-(3-((5-((4-Carbamimidoyl-2-fluorophenoxy)carbony...)
Affinity DataKi:  2.5nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571798(4-Carbamimidoyl-2-fluorophenyl 2-(ethyl(3-methoxy-...)
Affinity DataKi:  2.5nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571775(4-Carbamimidoyl-2-fluorophenyl 2-(4-((3-methoxy-3-...)
Affinity DataKi:  2.60nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571800(4-Carbamimidoyl-2-fluorophenyl 2-((4-methoxy-4-oxo...)
Affinity DataKi:  3nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Escherichia coli)
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM210928(UCP1164)
Affinity DataKi:  3.10nMAssay Description:Inhibition of recombinant Escherichia coli DHFR expressed in Escherichia coli BL21(DE3) cells assessed as reduction in NADPH oxidation using dihydrof...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Staphylococcus aureus)
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of recombinant Staphylococcus aureus DHFR expressed in Escherichia coli BL21(DE3) cells assessed as reduction in NADPH oxidation using dih...More data for this Ligand-Target Pair
LigandPNGBDBM50223637(Alphacemethadone | Alphacetylmethadol)
Affinity DataKi:  3.40nMAssay Description:Compound was evaluated for the inhibition of [3H]- naloxone binding to Opioid receptors in rat brain membrane in the presence of NaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571838(4-Carbamimidoyl-2-fluorophenyl 2-(ethyl(3-methoxy-...)
Affinity DataKi:  3.5nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571834(4-Carbamimidoyl-2-fluorophenyl (Z)-3-ethyl-2-((3-m...)
Affinity DataKi:  4nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571823(3-((6-((4-Carbamimidoylphenoxy)carbonyl)benzo[d]th...)
Affinity DataKi:  4.30nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
Lg Chem

US Patent
LigandPNGBDBM571807((1-(5-((4-Carbamimidoyl)phenoxy)carbonyl)thiazol-2...)
Affinity DataKi:  4.70nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Displayed 1 to 50 (of 2944 total ) | Next | Last >>
Jump to: