Affinity DataKi: 0.160nMAssay Description:Inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Binding affinity towards Opioid receptor mu 1 by displacing [3H]DAMGO in rat brain membranes.More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibition of [3H]NMS binding to rat heart Muscarinic acetylcholine receptor M2Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Concentration required for inhibition of [3H]DAMGO binding to Opioid receptor mu 1 in rat brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.370nMAssay Description:Inhibition of [3H]NMS binding to rat heart Muscarinic acetylcholine receptor M2Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.440nMAssay Description:Inhibition of [3H]NMS binding to rat heart Muscarinic acetylcholine receptor M2Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity for rat cortex Muscarinic acetylcholine receptor M1Checked by AuthorMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Camerino
Curated by ChEMBL
University Of Camerino
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Compound was tested for its binding affinity towards sigma 1 receptor using [3H]-(+)-pentazocine from guinea pig brainMore data for this Ligand-Target Pair
Affinity DataKi: 0.560nMAssay Description:Inhibition of [3H]NMS binding to rat heart Muscarinic acetylcholine receptor M2Checked by AuthorMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Camerino
Curated by ChEMBL
University Of Camerino
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:The compound was tested for the affinity on sigma 1 receptor using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Camerino
Curated by ChEMBL
University Of Camerino
Curated by ChEMBL
Affinity DataKi: 0.620nMAssay Description:Compound was tested for its binding affinity towards sigma 1 receptor using [3H]-(+)-pentazocine from guinea pig brainMore data for this Ligand-Target Pair
Affinity DataKi: 0.910nMAssay Description:Inhibition of [3H]NMS binding to rat heart Muscarinic acetylcholine receptor M2Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.950nMAssay Description:Binding affinity for rat cortex Muscarinic acetylcholine receptor M1Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.05nMAssay Description:Compound was tested for its binding affinity towards Alpha-1A adrenergic receptor using [3H]-prazosin from rat submaxillary glandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Camerino
Curated by ChEMBL
University Of Camerino
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Compound was tested for its binding affinity towards sigma 1 receptor using [3H]-(+)-pentazocine from guinea pig brainMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibition of NG 108-15 binding to Muscarinic acetylcholine receptor M4Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in HEK293 cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK293 cell membranes after 2 hrs by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in HEK293 cell membranes incubated for 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Binding affinity towards Opioid receptor mu 1More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Camerino
Curated by ChEMBL
University Of Camerino
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Inhibition of [3H]pentazocine binding to sigma-1 sites in guinea pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Binding affinity towards Opioid receptor mu 1 by displacing [3H]DAMGO in rat brain membranes.More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Camerino
Curated by ChEMBL
University Of Camerino
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:In vitro binding affinity for Sigma opioid receptor by displacement of [3H]-DTGMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Camerino
Curated by ChEMBL
University Of Camerino
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:In vitro binding affinity for Sigma opioid receptor by displacement of [3H]DTGMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of [3H]spiroperidol binding to Dopamine receptor D2 of rat striatal membranesMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Camerino
Curated by ChEMBL
University Of Camerino
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]-ketanserin from rat cortex 5-HT3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Binding affinity towards Opioid receptor mu 1 by displacing [3H]DAMGO in rat brain membranes.More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of [3H]NMS binding to rat heart Muscarinic acetylcholine receptor M2Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Inhibition of NG 108-15 binding to Muscarinic acetylcholine receptor M4Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor expressed in HEK293 cell membranes after 2 hrs by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in HEK293 cell membranes incubated for 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.93nMAssay Description:Compound was tested for its binding affinity towards Alpha-1B adrenergic receptor using [3H]-prazosin from rat liverMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Camerino
Curated by ChEMBL
University Of Camerino
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:In vitro binding affinity for Sigma opioid receptor by displacement of [3H]-DTGMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]- pyrilamine from rat brain membrane Histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of [3H]NMS binding to rat submaxillary gland Muscarinic acetylcholine receptor M3Checked by AuthorMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Camerino
Curated by ChEMBL
University Of Camerino
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:In vitro binding affinity for Sigma opioid receptor by displacement of [3H]-DTGMore data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cell membranes incubated for 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Camerino
Curated by ChEMBL
University Of Camerino
Curated by ChEMBL
Affinity DataKi: 3.20nMAssay Description:Compound was tested for its binding affinity towards sigma 1 receptor using [3H]-(+)-pentazocine from guinea pig brainMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cell membranes incubated for 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]diprenorphine from human delta opioid receptor expressed in HEK293 cell membranes after 2 hrs by liquid scintillation spectrometr...More data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]diprenorphine from human delta opioid receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Binding affinity for rat cortex Muscarinic acetylcholine receptor M1Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair