Compile Data Set for Download or QSAR
maximum 50k data
Found 281 with Last Name = 'specklin' and Initial = 'jl'
TargetPeptide deformylase(Escherichia coli)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089194((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-2-hydroxymethyl-...)
Affinity DataIC50:  6nMAssay Description:Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.More data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50408913(CHEMBL2092878)
Affinity DataIC50:  9nMAssay Description:Inhibition of human Matrix metalloprotease-12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089199(3-(Naphthalene-2-sulfonyl)-heptanoic acid hydroxya...)
Affinity DataIC50:  9nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089201(3-(4-Acetylamino-benzenesulfonyl)-heptanoic acid h...)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067069(CHEMBL128220 | sodium salt-Sulfuric acid mono-[2-(...)
Affinity DataIC50:  12nMAssay Description:Inhibition of beta-lactamase of Citrobacter freundii 1982 (class C)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089196(3-Benzenesulfonyl-heptanoic acid hydroxyamide | CH...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human Matrix metalloprotease-12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067069(CHEMBL128220 | sodium salt-Sulfuric acid mono-[2-(...)
Affinity DataIC50:  12nMAssay Description:Inhibition of beta-lactamase of Citrobacter freundii 1982 (class C)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089199(3-(Naphthalene-2-sulfonyl)-heptanoic acid hydroxya...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human Matrix metalloprotease-12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089198(3-Cyclohexanesulfonyl-heptanoic acid hydroxyamide ...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human Matrix metalloprotease-12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067060(CHEMBL128523 | Sodium; (1S,5R)-2-tert-butoxycarbon...)
Affinity DataIC50:  15nMAssay Description:Inhibition of P. aeruginosa 18SH Beta-lactamase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50021959(CHEMBL777 | MM 14151 | US9120808, Clavulanic acid ...)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity against Escherichia coli TEM-3 Beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50369525(CHEMBL1788203)
Affinity DataIC50:  16nMAssay Description:Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067070(CHEMBL355579 | sodium salt -tert-butyl 7-oxo-6-(su...)
Affinity DataIC50:  20nMAssay Description:Inhibition of beta-lactamase of Citrobacter freundii 1982 (class C)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089196(3-Benzenesulfonyl-heptanoic acid hydroxyamide | CH...)
Affinity DataIC50:  22nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089199(3-(Naphthalene-2-sulfonyl)-heptanoic acid hydroxya...)
Affinity DataIC50:  23nMAssay Description:Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067058(CHEMBL338157 | Sodium; (1S,5R)-2-(3-carbamoyl-phen...)
Affinity DataIC50:  24nMAssay Description:Inhibition of P. aeruginosa 18SH Beta-lactamase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067055(CHEMBL338933 | Sodium; (1S,5R)-2-[2-(4-hydroxy-phe...)
Affinity DataIC50:  25nMAssay Description:Inhibition of P. aeruginosa 18SH Beta-lactamase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067069(CHEMBL128220 | sodium salt-Sulfuric acid mono-[2-(...)
Affinity DataIC50:  26nMAssay Description:Inhibition of beta-lactamase of Pseudomonas aeruginosa 18 SH (class C)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50408523(CHEMBL2079714)
Affinity DataIC50:  27nMAssay Description:Inhibition of P. aeruginosa 18SH Beta-lactamase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067070(CHEMBL355579 | sodium salt -tert-butyl 7-oxo-6-(su...)
Affinity DataIC50:  28nMAssay Description:Inhibition of beta-lactamase of Pseudomonas aeruginosa 18 SH (class C)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067053(CHEMBL127782 | Sodium; (1S,5R)-2-benzyloxycarbonyl...)
Affinity DataIC50:  31nMAssay Description:Inhibitory activity against Escherichia coli TEM-3 Beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089209(3-(4-Methoxy-benzenesulfonyl)-heptanoic acid hydro...)
Affinity DataIC50:  31nMAssay Description:Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067066(CHEMBL340707 | Sodium; (1S,4R,5S)-2-benzyloxycarbo...)
Affinity DataIC50:  35nMAssay Description:Inhibitory activity against Escherichia coli TEM-3 Beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089196(3-Benzenesulfonyl-heptanoic acid hydroxyamide | CH...)
Affinity DataIC50:  35nMAssay Description:Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067050(CHEMBL336630 | Sodium; (1S,5R)-7-oxo-2-(piperidin-...)
Affinity DataIC50:  39nMAssay Description:Inhibition of P. aeruginosa 18SH Beta-lactamase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50369525(CHEMBL1788203)
Affinity DataIC50:  42nMAssay Description:Inhibition of human Matrix metalloprotease-12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067051(CHEMBL130187 | Sodium; (1S,5R)-7-oxo-2-(4-ureido-p...)
Affinity DataIC50:  48nMAssay Description:Inhibition of P. aeruginosa 18SH Beta-lactamase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067068((2S,5R)-2-(4-Carbamoyl-phenylcarbamoyl)-7-oxo-2,6-...)
Affinity DataIC50:  53nMAssay Description:Inhibition of beta-lactamase of Citrobacter freundii 1982 (class C)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089198(3-Cyclohexanesulfonyl-heptanoic acid hydroxyamide ...)
Affinity DataIC50:  54nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067047(CHEMBL341484 | Sodium; (1S,5R)-2-[2-(2,6-dimethyl-...)
Affinity DataIC50:  55nMAssay Description:Inhibition of P. aeruginosa 18SH Beta-lactamase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089204(3-(Naphthalene-2-sulfinyl)-heptanoic acid hydroxya...)
Affinity DataIC50:  64nMAssay Description:Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089199(3-(Naphthalene-2-sulfonyl)-heptanoic acid hydroxya...)
Affinity DataIC50:  70nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50369525(CHEMBL1788203)
Affinity DataIC50:  79nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089217(3-(3-Methoxy-benzenesulfonyl)-heptanoic acid hydro...)
Affinity DataIC50:  86nMAssay Description:Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50076680(CHEMBL6461 | Ro-48-1220 | Sodium; (2S,3R,5R)-3-((Z...)
Affinity DataIC50:  90nMAssay Description:Compound was tested for inhibition of Beta-lactamase from PSE-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067065(CHEMBL130854 | Sodium; (1S,5R)-2-[2-amino-2-(4-hyd...)
Affinity DataIC50:  90nMAssay Description:Inhibition of P. aeruginosa 18SH Beta-lactamase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089197(3-Benzenesulfinyl-heptanoic acid hydroxyamide | CH...)
Affinity DataIC50:  93nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089215(3-(3-Methoxy-benzenesulfinyl)-heptanoic acid hydro...)
Affinity DataIC50:  94nMAssay Description:Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089216(3-Benzenesulfonyl-3-furan-2-yl-N-hydroxy-propionam...)
Affinity DataIC50:  94nMAssay Description:Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089210(3-(4-Methoxy-benzenesulfinyl)-heptanoic acid hydro...)
Affinity DataIC50:  99nMAssay Description:Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase OXA-1(Escherichia coli (Enterobacteria))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50076680(CHEMBL6461 | Ro-48-1220 | Sodium; (2S,3R,5R)-3-((Z...)
Affinity DataIC50:  100nMAssay Description:Compound was tested for inhibition of Beta-lactamase from OXA-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase OXA-1(Escherichia coli (Enterobacteria))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50076680(CHEMBL6461 | Ro-48-1220 | Sodium; (2S,3R,5R)-3-((Z...)
Affinity DataIC50:  100nMAssay Description:Compound was tested for inhibition of Beta-lactamase from OXA-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089197(3-Benzenesulfinyl-heptanoic acid hydroxyamide | CH...)
Affinity DataIC50:  100nMAssay Description:Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089198(3-Cyclohexanesulfonyl-heptanoic acid hydroxyamide ...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089196(3-Benzenesulfonyl-heptanoic acid hydroxyamide | CH...)
Affinity DataIC50:  110nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067057(CHEMBL340937 | Sodium; (1S,5R)-2-((E)-3-1H-imidazo...)
Affinity DataIC50:  110nMAssay Description:Inhibition of P. aeruginosa 18SH Beta-lactamase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089200(3-(4-Bromo-benzenesulfonyl)-heptanoic acid hydroxy...)
Affinity DataIC50:  120nMAssay Description:Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50076680(CHEMBL6461 | Ro-48-1220 | Sodium; (2S,3R,5R)-3-((Z...)
Affinity DataIC50:  130nMAssay Description:Compound was tested for inhibition of Beta-lactamase from RTEM-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50089212(3-Benzenesulfonyl-octanoic acid hydroxyamide | CHE...)
Affinity DataIC50:  140nMAssay Description:Inhibitory activity against isolated Escherichia coli peptidyl deformylase (PDF) enzyme containing iron.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50067062(CHEMBL415234 | Sodium; (1S,6R)-2-tert-butoxycarbon...)
Affinity DataIC50:  145nMAssay Description:Inhibition of P. aeruginosa 18SH Beta-lactamase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 281 total ) | Next | Last >>
Jump to: