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Found 393 with Last Name = 'speth' and Initial = 'rc'
TargetType-1 angiotensin II receptor A(RAT)
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50043280(4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidaz...)
Affinity DataKi:  0.230nMAssay Description:Displacement of [125I]SI-Ang2 from AT1 receptor in Sprague-Dawley rat liver membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50228201(CHEMBL265084)
Affinity DataKi:  0.460nMAssay Description:Tested for inhibition of radioligand [Sar1,Ile5,8]AII binding to angiotensin II receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50228201(CHEMBL265084)
Affinity DataKi:  0.740nMAssay Description:Tested for inhibition of radioligand [Sar1,Ile5,8]AII binding to angiotensin II receptor in rat uterusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50266734(CHEMBL4096081)
Affinity DataKi:  0.790nMAssay Description:Antagonist activity at human MC4R expressed in CHO cells assessed as inhibition of aplha MSH-induced cAMP activation after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50228204(CHEMBL405389)
Affinity DataKi:  0.850nMAssay Description:Tested for inhibition of radioligand [Sar1,Ile5,8]AII binding to angiotensin II receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50228203(CHEMBL262025)
Affinity DataKi:  1nMAssay Description:Tested for inhibition of radioligand [Sar1,Ile5,8]AII binding to angiotensin II receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50228204(CHEMBL405389)
Affinity DataKi:  1.20nMAssay Description:Tested for inhibition of radioligand [Sar1,Ile5,8]AII binding to angiotensin II receptor in rat uterusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50236697(5-L-isoleucineangiotensin II | 5-isoleucine-angiot...)
Affinity DataKi:  1.40nMAssay Description:Tested for inhibition of radioligand [Sar1,Ile5,8]AII binding to angiotensin II receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50228198(CHEMBL414796)
Affinity DataKi:  1.5nMAssay Description:Tested for inhibition of radioligand [Sar1,Ile5,8]AII binding to angiotensin II receptor in rat uterusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50228199(ANGIOTENSIN AMIDE | Angiotensinamide)
Affinity DataKi:  1.60nMAssay Description:Tested for inhibition of radioligand [Sar1,Ile5,8]AII binding to angiotensin II receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50228200(CHEMBL217516)
Affinity DataKi:  1.60nMAssay Description:Tested for inhibition of radioligand [Sar1,Ile5,8]AII binding to angiotensin II receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50228203(CHEMBL262025)
Affinity DataKi:  1.70nMAssay Description:Tested for inhibition of radioligand [Sar1,Ile5,8]AII binding to angiotensin II receptor in rat uterusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50228198(CHEMBL414796)
Affinity DataKi:  1.80nMAssay Description:Tested for inhibition of radioligand [Sar1,Ile5,8]AII binding to angiotensin II receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50236697(5-L-isoleucineangiotensin II | 5-isoleucine-angiot...)
Affinity DataKi:  1.90nMAssay Description:Tested for inhibition of radioligand [Sar1,Ile5,8]AII binding to angiotensin II receptor in rat uterusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50228199(ANGIOTENSIN AMIDE | Angiotensinamide)
Affinity DataKi:  5.5nMAssay Description:Tested for inhibition of radioligand [Sar1,Ile5,8]AII binding to angiotensin II receptor in rat uterusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50228200(CHEMBL217516)
Affinity DataKi:  6.10nMAssay Description:Tested for inhibition of radioligand [Sar1,Ile5,8]AII binding to angiotensin II receptor in rat uterusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor A(RAT)
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50303975(3'-(4-(2-(1H-Tetrazol-5-yl)ethyl)benzyl)-1,7'-dime...)
Affinity DataKi:  13.4nMAssay Description:Displacement of [125I]SI-Ang2 from AT1 receptor in Sprague-Dawley rat liver membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Mus musculus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50266704(CHEMBL4083717)
Affinity DataKi:  15nMAssay Description:Antagonist activity at mouse MC4R expressed in HEK293 cells assessed as inhibition of NDP-MSH induced-cAMP accumulation after 2 hrs by alpha screen a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50228202(CHEMBL368638)
Affinity DataKi:  53nMAssay Description:Tested for inhibition of radioligand [Sar1,Ile5,8]AII binding to angiotensin II receptor in rat uterusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Mus musculus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50266713(CHEMBL4089759)
Affinity DataKi:  126nMAssay Description:Antagonist activity at mouse MC4R expressed in HEK293 cells assessed as inhibition of NDP-MSH induced-cAMP accumulation after 2 hrs by alpha screen a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor A(RAT)
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50303976(3'-(2-(4-(2-(1H-Tetrazol-5-yl)ethyl)phenoxy)ethyl)...)
Affinity DataKi:  1.62E+3nMAssay Description:Displacement of [125I]SI-Ang2 from AT1 receptor in Sprague-Dawley rat liver membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor A(RAT)
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50303977(3-(4-(2-(1,7'-Dimethyl-2'-propyl-1H,3'H-2,5'-biben...)
Affinity DataKi:  2.23E+3nMAssay Description:Displacement of [125I]SI-Ang2 from AT1 receptor in Sprague-Dawley rat liver membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor A(RAT)
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50303979(CHEMBL571763 | Ethyl 3-(4-(2-(1,7'-Dimethyl-2'-pro...)
Affinity DataKi:  2.53E+3nMAssay Description:Displacement of [125I]SI-Ang2 from AT1 receptor in Sprague-Dawley rat liver membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor A(RAT)
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50303978(1-(4-(2-(1H-tetrazol-5-yl)ethyl)benzyl)-4-methyl-2...)
Affinity DataKi:  2.84E+3nMAssay Description:Displacement of [125I]SI-Ang2 from AT1 receptor in Sprague-Dawley rat liver membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor A(RAT)
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50303980(1-(4-((1H-Tetrazol-5-yl)methoxy)benzyl)-4-methyl-2...)
Affinity DataKi:  5.06E+3nMAssay Description:Displacement of [125I]SI-Ang2 from AT1 receptor in Sprague-Dawley rat liver membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50228202(CHEMBL368638)
Affinity DataKi:  9.31E+3nMAssay Description:Tested for inhibition of radioligand [Sar1,Ile5,8]AII binding to angiotensin II receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor A(RAT)
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50303981(CHEMBL567063 | Ethyl 3-(4-((4-Methyl-2-propyl-1H-b...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]SI-Ang2 from AT1 receptor in Sprague-Dawley rat liver membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor A(RAT)
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50303984(CHEMBL565379 | Ethyl 2-Methyl-2-(4-((4-methyl-2-pr...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]SI-Ang2 from AT1 receptor in Sprague-Dawley rat liver membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor A(RAT)
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50303982(CHEMBL567689 | Methyl 3-(4-((4-Methyl-2-propyl-1H-...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]SI-Ang2 from AT1 receptor in Sprague-Dawley rat liver membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor A(RAT)
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50303983(CHEMBL565793 | ethyl 2-(4-((4-methyl-2-propyl-1H-b...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]SI-Ang2 from AT1 receptor in Sprague-Dawley rat liver membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor A(RAT)
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50303985(CHEMBL567269 | Ethyl 2,2-Dimethyl-3-(4-(2-(4-methy...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]SI-Ang2 from AT1 receptor in Sprague-Dawley rat liver membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor A(RAT)
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50303986(CHEMBL584704 | Ethyl 2-Methyl-3-(4-(2-(4-methyl-2-...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]SI-Ang2 from AT1 receptor in Sprague-Dawley rat liver membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Mus musculus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50017181(CHEMBL441738)
Affinity DataIC50:  0.290nMAssay Description:Displacement of [125I]-NDP-MSH from mouse melanocortin receptor 1 expressed in HEK293 cell mebranes incubated for 1 hr by automatic gamma counting me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Mus musculus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50017181(CHEMBL441738)
Affinity DataIC50:  0.310nMAssay Description:Displacement of 125I-NDP-MSH from mouse MC1R expressed in HEK293 cells incubated for 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Mus musculus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50017181(CHEMBL441738)
Affinity DataIC50:  1.10nMAssay Description:Displacement of 125I-NDP-MSH from mouse MC4R expressed in HEK293 cells incubated for 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Mus musculus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50017181(CHEMBL441738)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [125I]-NDP-MSH from mouse melanocortin receptor 4 expressed in HEK293 cell mebranes incubated for 1 hr by automatic gamma counting me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Mus musculus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50258965(CHEMBL4102048)
Affinity DataIC50:  1.90nMAssay Description:Displacement of [125I]-NDP-MSH from mouse melanocortin receptor 4 expressed in HEK293 cell mebranes incubated for 1 hr by automatic gamma counting me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Mus musculus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50017181(CHEMBL441738)
Affinity DataIC50:  2nMAssay Description:Displacement of [125I]-NDP-MSH from mouse MC4R expressed in HEK293 cells after 1 hr by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Mus musculus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50017181(CHEMBL441738)
Affinity DataIC50:  4.20nMAssay Description:Displacement of 125I-NDP-MSH from mouse MC3R expressed in HEK293 cells incubated for 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50403547(ATROPEN | ATROPINE)
Affinity DataIC50:  4.80nMAssay Description:Concentration of compound for 50% displacement of [3H]QNB from Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM31046(3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphe...)
Affinity DataIC50:  5.20nMAssay Description:Concentration of compound for 50% displacement of [3H]WB-4101 from Alpha-1 adrenergic receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Mus musculus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50017181(CHEMBL441738)
Affinity DataIC50:  5.30nMAssay Description:Displacement of [125I]-NDP-MSH from mouse MC3R expressed in HEK293 cells after 1 hr by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50258965(CHEMBL4102048)
Affinity DataIC50:  7.5nMAssay Description:Displacement of [125I]-NDP-MSH from human melanocortin receptor 4 expressed in HEK293 cell mebranes incubated for 1 hr by automatic gamma counting me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Mus musculus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50514457(CHEMBL4565367)
Affinity DataIC50:  8.20nMAssay Description:Displacement of [125I]-NDP-MSH from mouse melanocortin receptor 4 expressed in HEK293 cell mebranes incubated for 1 hr by automatic gamma counting me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Mus musculus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50017181(CHEMBL441738)
Affinity DataIC50:  8.20nMAssay Description:Displacement of [125I]-NDP-MSH from mouse melanocortin receptor 3 expressed in HEK293 cell mebranes incubated for 1 hr by automatic gamma counting me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Mus musculus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50164804(CHEMBL3798421)
Affinity DataIC50:  9.90nMAssay Description:Displacement of 125I-NDP-MSH from mouse MC4R expressed in HEK293 cells incubated for 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Mus musculus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50164800(CHEMBL3798768)
Affinity DataIC50:  10nMAssay Description:Displacement of 125I-NDP-MSH from mouse MC4R expressed in HEK293 cells incubated for 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50017181(CHEMBL441738)
Affinity DataIC50:  10nMAssay Description:Displacement of [125I]-NDP-MSH from human melanocortin receptor 4 expressed in HEK293 cell mebranes incubated for 1 hr by automatic gamma counting me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Mus musculus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50164802(CHEMBL3799408)
Affinity DataIC50:  11nMAssay Description:Displacement of 125I-NDP-MSH from mouse MC4R expressed in HEK293 cells incubated for 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Mus musculus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50266704(CHEMBL4083717)
Affinity DataIC50:  13nMAssay Description:Displacement of [125I]-NDP-MSH from mouse MC4R expressed in HEK293 cells after 1 hr by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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