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Found 100 with Last Name = 'stanek' and Initial = 'j'
TargetAromatase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50405683(CHEMBL174909)
Affinity DataKi:  1.5nMAssay Description:Apparent inhibition constant (Ki) for cytochrome P450 19A1 with androstenedioneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50011767(1-(4-Amino-phenyl)-3-pentyl-3-aza-bicyclo[3.1.0]he...)
Affinity DataKi:  20nMAssay Description:Inhibition of human placental cytochrome P450 19A1 androstenedioneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50405688(CHEMBL174407)
Affinity DataKi:  50nMAssay Description:Inhibition of human placental cytochrome P450 19A1 androstenedioneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50011760(1-(4-Amino-phenyl)-3-aza-bicyclo[3.1.0]hexane-2,4-...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of human placental cytochrome P450 19A1 androstenedioneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of human placental cytochrome P450 19A1 with testosteroneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAromatase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50011762((1R,5S)1-(4-Amino-phenyl)-3-cyclohexylmethyl-3-aza...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibition of cytochrome P450 19A1 AromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50368644(CHEMBL1202793 | Sardomozide chloride)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity against S- adenosylmethionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50011762((1R,5S)1-(4-Amino-phenyl)-3-cyclohexylmethyl-3-aza...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibition of cytochrome P450 19A1 AromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50046197(4-{3-[(Z)-amino(imino)methyl]phenyl}pyrimidine-2-c...)
Affinity DataIC50:  6nMAssay Description:Inhibitory concentration of compound against S-Adenosylmethionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50046206(2,2'-bipyridine-6,6'-dicarboximidamide | CHEMBL151...)
Affinity DataIC50:  6nMAssay Description:Inhibitory concentration of compound against S-Adenosylmethionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50368645(CHEMBL1202792)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against S- adenosylmethionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50011762((1R,5S)1-(4-Amino-phenyl)-3-cyclohexylmethyl-3-aza...)
Affinity DataIC50:  12nMAssay Description:In vitro inhibition of estrogen production in hamster ovarian tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50011756(1-(4-Amino-phenyl)-3-cyclohexyl-3-aza-bicyclo[3.1....)
Affinity DataIC50:  13nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrnithine decarboxylase(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50005726(CHEMBL27061 | O-(3-Amino-2-fluoro-propyl)-hydroxyl...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against Rat liver ornithine decarboxylase(ODC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50011767(1-(4-Amino-phenyl)-3-pentyl-3-aza-bicyclo[3.1.0]he...)
Affinity DataIC50:  23nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50011766(1-(4-Amino-phenyl)-3-pentyl-3-aza-bicyclo[3.1.1]he...)
Affinity DataIC50:  31nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrnithine decarboxylase(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50005712((S)1-Amino-3-aminooxy-propan-2-ol | CHEMBL26435)
Affinity DataIC50:  33nMAssay Description:Inhibitory activity against Rat liver ornithine decarboxylase(ODC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrnithine decarboxylase(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50005719((APA)O-(3-Amino-propyl)-hydroxylamine | 3-AMINOOXY...)
Affinity DataIC50:  35nMAssay Description:Inhibitory activity against Rat liver ornithine decarboxylase(ODC)More data for this Ligand-Target Pair
TargetS-adenosylmethionine decarboxylase proenzyme(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50046189((2E)-2-{3-[(Z)-amino(imino)methyl]benzylidene}hydr...)
Affinity DataIC50:  36nMAssay Description:Inhibitory concentration of compound against S-Adenosylmethionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrnithine decarboxylase(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50005727(1-Amino-3-aminooxy-propan-2-ol | CHEMBL26857)
Affinity DataIC50:  39nMAssay Description:Inhibitory activity against Rat liver ornithine decarboxylase(ODC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrnithine decarboxylase(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50005725((R)1-Amino-3-aminooxy-propan-2-ol | CHEMBL284573)
Affinity DataIC50:  49nMAssay Description:Inhibitory activity against Rat liver ornithine decarboxylase(ODC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50011765(1-(4-Amino-phenyl)-3-heptyl-3-aza-bicyclo[3.1.1]he...)
Affinity DataIC50:  49nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50046196(3-((E)-{[(Z)-((2E)-2-{3-[(E)-amino(imino)methyl]be...)
Affinity DataIC50:  61nMAssay Description:Inhibitory concentration of compound against S-Adenosylmethionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50011768(1-(4-Amino-phenyl)-3-isobutyl-3-aza-bicyclo[3.1.1]...)
Affinity DataIC50:  62nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50046200((2E)-2-(1-{3-[(E)-amino(imino)methyl]phenyl}ethyli...)
Affinity DataIC50:  66nMAssay Description:Inhibitory concentration of compound against S-Adenosylmethionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50011756(1-(4-Amino-phenyl)-3-cyclohexyl-3-aza-bicyclo[3.1....)
Affinity DataIC50:  70nMAssay Description:In vitro inhibition of estrogen production in hamster ovarian tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50046190(6-((E)-{[(E)-amino(hydrazono)methyl]hydrazono}meth...)
Affinity DataIC50:  84nMAssay Description:Inhibitory concentration of compound against S-Adenosylmethionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50046193((2E)-2-(1-{3-[(E)-amino(imino)methyl]phenyl}propyl...)
Affinity DataIC50:  88nMAssay Description:Inhibitory concentration of compound against S-Adenosylmethionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50046210(6-((E)-{[(E)-amino(imino)methyl]hydrazono}methyl)p...)
Affinity DataIC50:  90nMAssay Description:Inhibitory concentration of compound against S-Adenosylmethionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50046209((2E)-2-{3-[(E)-amino(imino)methyl]benzylidene}-N'-...)
Affinity DataIC50:  92nMAssay Description:Inhibitory concentration of compound against S-Adenosylmethionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrnithine decarboxylase(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50005714(CHEMBL15650 | O-(3-Amino-2-chloro-propyl)-hydroxyl...)
Affinity DataIC50:  93nMAssay Description:Inhibitory activity against Rat liver ornithine decarboxylase(ODC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50011764(1-(4-Amino-phenyl)-3-cyclohexylmethyl-3-aza-bicycl...)
Affinity DataIC50:  97nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50011761(1-(4-Amino-phenyl)-3-propyl-3-aza-bicyclo[3.1.1]he...)
Affinity DataIC50:  111nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50046207(6-((E)-{[(E)-[(2E)-2-({6-[(E)-amino(imino)methyl]p...)
Affinity DataIC50:  120nMAssay Description:Inhibitory concentration of compound against S-Adenosylmethionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50046191((2E)-2-{3-[(E)-amino(imino)methyl]benzylidene}-N'-...)
Affinity DataIC50:  160nMAssay Description:Inhibitory concentration of compound against S-Adenosylmethionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50046204(4,4'-bipyridine-2,2'-dicarboximidamide | CHEMBL433...)
Affinity DataIC50:  180nMAssay Description:Inhibitory concentration of compound against S-Adenosylmethionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50046203(3-((E)-{[(E)-amino(hydrazono)methyl]hydrazono}meth...)
Affinity DataIC50:  210nMAssay Description:Inhibitory concentration of compound against S-Adenosylmethionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50011759(1-(4-Amino-phenyl)-3-decyl-3-aza-bicyclo[3.1.1]hep...)
Affinity DataIC50:  225nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50011762((1R,5S)1-(4-Amino-phenyl)-3-cyclohexylmethyl-3-aza...)
Affinity DataIC50:  230nMAssay Description:In vitro inhibition of progesterone production in hamster ovarian tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50011758(1-(4-Amino-phenyl)-3-(4-methoxy-benzyl)-3-aza-bicy...)
Affinity DataIC50:  240nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50046202(6-((E)-{[(E)-amino(hydroxyimino)methyl]hydrazono}m...)
Affinity DataIC50:  240nMAssay Description:Inhibitory concentration of compound against S-Adenosylmethionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50046195(4-((E)-{[(E)-amino(imino)methyl]hydrazono}methyl)p...)
Affinity DataIC50:  330nMAssay Description:Inhibitory concentration of compound against S-Adenosylmethionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50046194(4-((E)-{[(E)-amino(imino)methyl]hydrazono}methyl)p...)
Affinity DataIC50:  530nMAssay Description:Inhibitory concentration of compound against S-Adenosylmethionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50046212(1,1'-biphenyl-3,3'-dicarboximidamide | CHEMBL15062...)
Affinity DataIC50:  600nMAssay Description:Inhibitory concentration of compound against S-Adenosylmethionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50046192(6-((E)-{[(E)-amino(hydrazono)methyl]hydrazono}meth...)
Affinity DataIC50:  670nMAssay Description:Inhibitory concentration of compound against S-Adenosylmethionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive amine oxidase [copper-containing](Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50046207(6-((E)-{[(E)-[(2E)-2-({6-[(E)-amino(imino)methyl]p...)
Affinity DataIC50:  760nMAssay Description:In vitro inhibition of Diamine oxidase (DAO) from rat small intestine.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50011762((1R,5S)1-(4-Amino-phenyl)-3-cyclohexylmethyl-3-aza...)
Affinity DataIC50:  780nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive amine oxidase [copper-containing](Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50046196(3-((E)-{[(Z)-((2E)-2-{3-[(E)-amino(imino)methyl]be...)
Affinity DataIC50:  830nMAssay Description:In vitro inhibition of Diamine oxidase (DAO) from rat small intestine.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive amine oxidase [copper-containing](Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50046210(6-((E)-{[(E)-amino(imino)methyl]hydrazono}methyl)p...)
Affinity DataIC50:  870nMAssay Description:In vitro inhibition of Diamine oxidase (DAO) from rat small intestine.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive amine oxidase [copper-containing](Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50046203(3-((E)-{[(E)-amino(hydrazono)methyl]hydrazono}meth...)
Affinity DataIC50:  870nMAssay Description:In vitro inhibition of Diamine oxidase (DAO) from rat small intestine.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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