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Found 1775 with Last Name = 'strack' and Initial = 'a'
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50245192(3-((S)-4-(1-(3-ethoxyphenyl)-2-(2-fluoro-4-methylp...)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50245186(3-((S)-4-(1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazol...)
Affinity DataIC50:  0.0160nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50245205(2-((S)-1-(1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazol...)
Affinity DataIC50:  0.0180nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50263230(3-(4-(1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-(2...)
Affinity DataIC50:  0.0300nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50263229(3-(4-(1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-(4...)
Affinity DataIC50:  0.0300nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50343722(3-(4-(5-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-4-(2...)
Affinity DataIC50:  0.0340nMAssay Description:Displacement of [I125]-CCK8 from human CCK1 receptor expressed in CHO Flip cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50245195(2-(((R)-1-(1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazo...)
Affinity DataIC50:  0.0390nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50245187(3-(4-(1-(3-ethoxyphenyl)-2-(2-fluoro-4-methylpheny...)
Affinity DataIC50:  0.0400nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50245188(3-((S)-3-((carboxymethoxy)methyl)-4-(1-(3-ethoxyph...)
Affinity DataIC50:  0.0410nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50245201(3-(((S)-1-(1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazo...)
Affinity DataIC50:  0.0520nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50245189(3-((R)-3-(acetamidomethyl)-4-(1-(3-ethoxyphenyl)-2...)
Affinity DataIC50:  0.0580nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50245187(3-(4-(1-(3-ethoxyphenyl)-2-(2-fluoro-4-methylpheny...)
Affinity DataIC50:  0.0600nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50245190(3-((S)-4-(1-(3-ethoxyphenyl)-2-(2-fluoro-4-methylp...)
Affinity DataIC50:  0.0670nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50263227(3-(4-(2-(2,4-difluorophenyl)-1-(3-ethoxyphenyl)-1H...)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50263226(3-(4-(1-(3-ethoxyphenyl)-2-(4-fluorophenyl)-1H-imi...)
Affinity DataIC50:  0.0800nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50245182(3-((S)-3-(acetamidomethyl)-4-(1-(3-ethoxyphenyl)-2...)
Affinity DataIC50:  0.0800nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50245184(3-((S)-4-(1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazol...)
Affinity DataIC50:  0.0800nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50245191(3-((R)-4-(1-(3-ethoxyphenyl)-2-(2-fluoro-4-methylp...)
Affinity DataIC50:  0.0970nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267545((4-(3-cyclopropyl-5-(trifluoromethyl)phenylsulfony...)
Affinity DataIC50:  0.100nMAssay Description:Displacement of [3H]SR141716 from human recombinant CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50245185(3-((R)-4-(1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazol...)
Affinity DataIC50:  0.110nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50245183(3-((R)-4-(1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazol...)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50245180(3-(4-(1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazole-4-...)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50263225((1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-(4-fluo...)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50245180(3-(4-(1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazole-4-...)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50245181(3-((R)-3-((carboxymethoxy)methyl)-4-(1-(3-ethoxyph...)
Affinity DataIC50:  0.140nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50263228(3-(4-(1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-p-...)
Affinity DataIC50:  0.140nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50262862(3-(4-(1-(3-methoxyphenyl)-2-p-tolyl-1H-imidazole-4...)
Affinity DataIC50:  0.140nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50343703((5-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-4-p-tolyl...)
Affinity DataIC50:  0.180nMAssay Description:Displacement of [I125]-CCK8 from human CCK1 receptor expressed in CHO Flip cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267545((4-(3-cyclopropyl-5-(trifluoromethyl)phenylsulfony...)
Affinity DataIC50:  0.200nMAssay Description:Displacement of [3H] SR141716 from rat recombinant CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50263186((1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-p-tolyl...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50320187((2R)-N-(7'-(2-CHLOROPHENYL)-6'-(4-CHLOROPHENYL)-3'...)
Affinity DataIC50:  0.200nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50316524(CHEMBL1095158 | N-[(4R)-6-(4-Chlorophenyl)-7-(2,4-...)
Affinity DataIC50:  0.200nMAssay Description:Displacement of [3H]CP55940 from human recombinant cannabinoid CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50316527(CHEMBL1097841 | N-[(4R)-6-(4-Chlorophenyl)-7-(2,4-...)
Affinity DataIC50:  0.200nMAssay Description:Displacement of [3H]CP55940 from human recombinant cannabinoid CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50316529(CHEMBL1095151 | N-[(4R)-6-(4-Chlorophenyl)-7-(2,4-...)
Affinity DataIC50:  0.200nMAssay Description:Displacement of [3H]CP55940 from human recombinant cannabinoid CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267907((4-(3-(4H-1,2,4-triazol-3-yl)-5-(trifluoromethyl)p...)
Affinity DataIC50:  0.200nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50245199((2R)-1-(1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazole-...)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50343721(3-(4-(4-(2-fluoro-4-methylphenyl)-5-(4-methoxyphen...)
Affinity DataIC50:  0.220nMAssay Description:Displacement of [I125]-CCK8 from human CCK1 receptor expressed in CHO Flip cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50263185((1-(3-ethoxyphenyl)-2-(2-fluoro-4-methylphenyl)-1H...)
Affinity DataIC50:  0.240nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50245204((2S)-1-(1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazole-...)
Affinity DataIC50:  0.240nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50245194(((R)-1-(1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazole-...)
Affinity DataIC50:  0.240nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50245196(CHEMBL450443 | N-(((S)-1-(1-(3-ethoxyphenyl)-2-p-t...)
Affinity DataIC50:  0.25nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50343711((4-(2-fluoro-4-methylphenyl)-5-(4-methoxyphenyl)py...)
Affinity DataIC50:  0.260nMAssay Description:Displacement of [I125]-CCK8 from human CCK1 receptor expressed in CHO Flip cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50205166(CHEMBL231636 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50119367((3R)-N-[(2R)-3-(4-chlorophenyl)-1-{4-cyclohexyl-4-...)
Affinity DataIC50:  0.300nMAssay Description:Evaluated for binding affinity against Melanocortin-4 receptor by displacing [125I]-NDP-alpha-MSH radioligand expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200841(CHEMBL220360 | MK-0364 | MK-0634 | N-((2S,3S)-4-(4...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of [3H]CP-55940 binding to human recombinant CB1 receptor in CHO cellsMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50320184(CHEMBL1086494 | rac-N-(7'-(2-chlorophenyl)-6'-(4-c...)
Affinity DataIC50:  0.300nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200841(CHEMBL220360 | MK-0364 | MK-0634 | N-((2S,3S)-4-(4...)
Affinity DataIC50:  0.300nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200841(CHEMBL220360 | MK-0364 | MK-0634 | N-((2S,3S)-4-(4...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200841(CHEMBL220360 | MK-0364 | MK-0634 | N-((2S,3S)-4-(4...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of cannabinoid CB1 receptorMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200841(CHEMBL220360 | MK-0364 | MK-0634 | N-((2S,3S)-4-(4...)
Affinity DataIC50:  0.300nMAssay Description:Inverse agonist activity at cannabinoid CB1 receptor (unknown origin)More data for this Ligand-Target Pair
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