Compile Data Set for Download or QSAR
maximum 50k data
Found 290 with Last Name = 'sviridov' and Initial = 's'
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424785(CHEMBL2315102)
Affinity DataIC50:  3nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424783(CHEMBL2315104)
Affinity DataIC50:  6nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin-linked protein kinase(Homo sapiens (Human))
Dermira (Canada)

US Patent
LigandPNGBDBM123945(US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-5-...)
Affinity DataIC50:  7nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424785(CHEMBL2315102)
Affinity DataIC50:  7nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424790(CHEMBL2315095)
Affinity DataIC50:  10nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin-linked protein kinase(Homo sapiens (Human))
Dermira (Canada)

US Patent
LigandPNGBDBM123951(US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-be...)
Affinity DataIC50:  10nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424789(CHEMBL2315096)
Affinity DataIC50:  10nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin-linked protein kinase(Homo sapiens (Human))
Dermira (Canada)

US Patent
LigandPNGBDBM124052(US8754233, 5-(3-Amino-propyl)-4-benzothiazol-2-yl-...)
Affinity DataIC50:  10nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424823(CHEMBL2315110)
Affinity DataIC50:  11nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424802(CHEMBL2315130)
Affinity DataIC50:  12nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424800(CHEMBL2315132)
Affinity DataIC50:  12nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424802(CHEMBL2315130)
Affinity DataIC50:  14nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424818(CHEMBL2315115)
Affinity DataIC50:  15nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50304941((R)-N-(2-hydroxy-2-phenylethyl)-6-(4-(2-(trifluoro...)
Affinity DataIC50:  15nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50304937(CHEMBL591796 | N-phenethyl-6-(4-(2-(trifluoromethy...)
Affinity DataIC50:  18nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424800(CHEMBL2315132)
Affinity DataIC50:  18nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424786(CHEMBL2315101)
Affinity DataIC50:  18nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50304937(CHEMBL591796 | N-phenethyl-6-(4-(2-(trifluoromethy...)
Affinity DataIC50:  18nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50304941((R)-N-(2-hydroxy-2-phenylethyl)-6-(4-(2-(trifluoro...)
Affinity DataIC50:  19nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin-linked protein kinase(Homo sapiens (Human))
Dermira (Canada)

US Patent
LigandPNGBDBM124067(US8754233, N3-(2-Amino-ethyl)-4-benzothiazol-2-yl-...)
Affinity DataIC50:  20nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIntegrin-linked protein kinase(Homo sapiens (Human))
Dermira (Canada)

US Patent
LigandPNGBDBM124022(US8754233, 4-Benzothiazol-2-yl-5-(3-methylamino-pr...)
Affinity DataIC50:  20nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIntegrin-linked protein kinase(Homo sapiens (Human))
Dermira (Canada)

US Patent
LigandPNGBDBM123930(US8754233, 2-(3-Amino-1H-pyrazol-4-yl)-5-fluoro-be...)
Affinity DataIC50:  20nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424787(CHEMBL2315100)
Affinity DataIC50:  21nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424794(CHEMBL2315412)
Affinity DataIC50:  21nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424826(CHEMBL2315107)
Affinity DataIC50:  23nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424787(CHEMBL2315100)
Affinity DataIC50:  24nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424794(CHEMBL2315412)
Affinity DataIC50:  24nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424788(CHEMBL2315099)
Affinity DataIC50:  25nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301062(CHEMBL572098 | N-(2-cyclopropylethyl)-6-(4-(2-(tri...)
Affinity DataIC50:  25nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50304942((S)-N-(2-hydroxy-2-phenylethyl)-6-(4-(2-(trifluoro...)
Affinity DataIC50:  25nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50371042(CHEMBL229212)
Affinity DataIC50:  26nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424788(CHEMBL2315099)
Affinity DataIC50:  28nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424817(CHEMBL2315116)
Affinity DataIC50:  31nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424821(CHEMBL2315112)
Affinity DataIC50:  32nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424822(CHEMBL2315111)
Affinity DataIC50:  33nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424790(CHEMBL2315095)
Affinity DataIC50:  34nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424797(CHEMBL2315135)
Affinity DataIC50:  34nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50371042(CHEMBL229212)
Affinity DataIC50:  37nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301062(CHEMBL572098 | N-(2-cyclopropylethyl)-6-(4-(2-(tri...)
Affinity DataIC50:  39nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin-linked protein kinase(Homo sapiens (Human))
Dermira (Canada)

US Patent
LigandPNGBDBM123933(US8754233, 2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-5-...)
Affinity DataIC50:  40nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIntegrin-linked protein kinase(Homo sapiens (Human))
Dermira (Canada)

US Patent
LigandPNGBDBM124001(US8754233, 4-(5-Fluoro-benzothiazol-2-yl)-5-methyl...)
Affinity DataIC50:  40nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIntegrin-linked protein kinase(Homo sapiens (Human))
Dermira (Canada)

US Patent
LigandPNGBDBM123965(US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-be...)
Affinity DataIC50:  40nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIntegrin-linked protein kinase(Homo sapiens (Human))
Dermira (Canada)

US Patent
LigandPNGBDBM123943(US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-4-...)
Affinity DataIC50:  40nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIntegrin-linked protein kinase(Homo sapiens (Human))
Dermira (Canada)

US Patent
LigandPNGBDBM123992(US8754233, 4-(5-Fluoro-6-methoxy-benzothiazol-2-yl...)
Affinity DataIC50:  40nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424783(CHEMBL2315104)
Affinity DataIC50:  41nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424826(CHEMBL2315107)
Affinity DataIC50:  42nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin-linked protein kinase(Homo sapiens (Human))
Dermira (Canada)

US Patent
LigandPNGBDBM123946(US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-5-...)
Affinity DataIC50:  50nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIntegrin-linked protein kinase(Homo sapiens (Human))
Dermira (Canada)

US Patent
LigandPNGBDBM123969(US8754233, 2-(5-Amino-3-pyridin-4-yl-1H-pyrazol-4-...)
Affinity DataIC50:  50nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIntegrin-linked protein kinase(Homo sapiens (Human))
Dermira (Canada)

US Patent
LigandPNGBDBM123999(US8754233, 4-(5-Fluoro-6-methyl-benzothiazol-2-yl)...)
Affinity DataIC50:  50nMT: 2°CAssay Description:5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424795(CHEMBL2315137)
Affinity DataIC50:  58nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 290 total ) | Next | Last >>
Jump to: