Affinity DataKi: 490nMAssay Description:Compound was tested for inhibitory activity against plasmepsin IIMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMAssay Description:Compound was tested for inhibitory activity against cathepsin DMore data for this Ligand-Target Pair
Affinity DataKi: 1.80E+3nMAssay Description:Compound was tested for inhibitory activity against cathepsin DMore data for this Ligand-Target Pair
Affinity DataKi: 5.30E+3nMAssay Description:Compound was tested for inhibitory activity against cathepsin DMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: 0.640nMAssay Description:Inhibition of mTOR (unknown origin) using U-Light-4E-BP1 peptide as a substrate in the presence of ATP incubated for 30 mins by Lance ultra assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of HDAC1 (unknown origin) using Ac-peptide as a substrate pretreated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of HDAC1 (unknown origin) using Ac-peptide as a substrate pretreated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of HDAC2 (unknown origin) using Ac-peptide as a substrate pretreated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of HDAC2 (unknown origin) using Ac-peptide as a substrate pretreated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: 4.10nMAssay Description:Inhibition of mTOR (unknown origin) using U-Light-4E-BP1 peptide as a substrate in the presence of ATP incubated for 30 mins by Lance ultra assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of HDAC3 (unknown origin) using Ac-peptide as a substrate pretreated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: 6.70nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-peptide as a substrate pretreated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: 7.10nMAssay Description:Inhibition of HDAC3 (unknown origin) using Ac-peptide as a substrate pretreated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: 7.70nMAssay Description:Inhibition of mTOR (unknown origin) using U-Light-4E-BP1 peptide as a substrate in the presence of ATP incubated for 30 mins by Lance ultra assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: 9.5nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-peptide as a substrate pretreated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-peptide as a substrate pretreated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of mTOR (unknown origin) using U-Light-4E-BP1 peptide as a substrate in the presence of ATP incubated for 30 mins by Lance ultra assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of HDAC1 (unknown origin) using Ac-peptide as a substrate pretreated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of HDAC1 (unknown origin) using Ac-peptide as a substrate pretreated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-peptide as a substrate pretreated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of HDAC2 (unknown origin) using Ac-peptide as a substrate pretreated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of HDAC2 (unknown origin) using Ac-peptide as a substrate pretreated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of HDAC3 (unknown origin) using Ac-peptide as a substrate pretreated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 3a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 6a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 3a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 6a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of HDAC3 (unknown origin) using Ac-peptide as a substrate pretreated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 4a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 4a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: 92nMAssay Description:Inhibition of mTOR (unknown origin) using U-Light-4E-BP1 peptide as a substrate in the presence of ATP incubated for 30 mins by Lance ultra assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
West China Hospital Of Sichuan University
Curated by ChEMBL
West China Hospital Of Sichuan University
Curated by ChEMBL
Affinity DataIC50: 92nMAssay Description:Inhibition of His-tagged full length recombinant BRD4 (unknown origin) (21 to 153 residues) using SGRGK(Ac)GGK(Ac)GLGK(Ac)GGAK(Ac)RHRK(Biotin)-OH as ...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
West China Hospital Of Sichuan University
Curated by ChEMBL
West China Hospital Of Sichuan University
Curated by ChEMBL
Affinity DataIC50: 92nMAssay Description:Inhibition of His-tagged full length recombinant BRD4 (unknown origin) (21 to 153 residues) using SGRGK(Ac)GGK(Ac)GLGK(Ac)GGAK(Ac)RHRK(Biotin)-OH as ...More data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 96nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 96nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 97nMAssay Description:Binding affinity to human GST-tagged PPAR-alpha LBD expressed in Escherichia coli BL21 (DE3) PlysS after 30 mins in presence of fluorescein ligand FL...More data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 97nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 5a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 97nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 5a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
West China Hospital Of Sichuan University
Curated by ChEMBL
West China Hospital Of Sichuan University
Curated by ChEMBL
Affinity DataIC50: 107nMAssay Description:Inhibition of His-tagged full length recombinant BRD4 (unknown origin) (21 to 153 residues) using SGRGK(Ac)GGK(Ac)GLGK(Ac)GGAK(Ac)RHRK(Biotin)-OH as ...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
West China Hospital Of Sichuan University
Curated by ChEMBL
West China Hospital Of Sichuan University
Curated by ChEMBL
Affinity DataIC50: 107nMAssay Description:Inhibition of His-tagged full length recombinant BRD4 (unknown origin) (21 to 153 residues) using SGRGK(Ac)GGK(Ac)GLGK(Ac)GGAK(Ac)RHRK(Biotin)-OH as ...More data for this Ligand-Target Pair
Affinity DataIC50: 122nMAssay Description:Displacement of fluorescent labeled derivative from recombinant human hepatic glucokinase incubated for 30 mins in presence of 12 mM glucose by fluor...More data for this Ligand-Target Pair
Affinity DataIC50: 123nMAssay Description:Displacement of fluorescent labeled derivative from recombinant human hepatic glucokinase incubated for 30 mins in presence of 12 mM glucose by fluor...More data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 6a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 6a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 141nMAssay Description:Binding affinity to human His-tagged PPARgamma LBD (Q203-Y477) expressed in Escherichia coli BL21 (DE3) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 162nMAssay Description:Binding affinity to human His-tagged PPARgamma LBD (Q203-Y477) expressed in Escherichia coli BL21 (DE3) by fluorescence polarization assayMore data for this Ligand-Target Pair