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Found 266 with Last Name = 'tien' and Initial = 'e'
TargetCytochrome P450 3A4(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50553436(CHEMBL4744041)
Affinity DataKi:  5.00E+4nMAssay Description:Time-dependent inhibition of CYP3A4 in human liver microsomes using testosterone in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50583942(CHEMBL5088454)
Affinity DataIC50:  0.130nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM324380(1-(tert-butyl)-N- (2-(2-((1- methyl-1H-pyrazol-4- ...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50553434(CHEMBL4782313)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged BTK expressed in baculovirus infected Sf21 insect cells using fluorescein-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50553431(CHEMBL4754065)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged BTK expressed in baculovirus infected Sf21 insect cells using fluorescein-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50583944(CHEMBL5089878)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM324290(5-(tert-butyl)-N-(2-(2-((1-methyl-1H-pyrazol-4-yl)...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM324294(3-(tert-butyl)-N-(2-(2-((1-methyl-1H-pyrazol-4-yl)...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50583938(CHEMBL5090290)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50553435(CHEMBL4796367)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged BTK expressed in baculovirus infected Sf21 insect cells using fluorescein-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50553426(CHEMBL4746275)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged BTK expressed in baculovirus infected Sf21 insect cells using fluorescein-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM324293((R)-5-(tert-butyl)-N-(2-(2-((1-methyl-1H-pyrazol-4...)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50583946(CHEMBL5076817)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50583947(CHEMBL5085931)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50583941(CHEMBL5087183)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM324285((R)-1-(tert-butyl)-N-(8-(2-((1-methyl-1H-pyrazol-4...)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM324288((R)-1-(tert-butyl)-N-(2-(2-methoxyethyl)-8-(2-((1-...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM324284((R)-1-(tert-butyl)-N-(8-(2-((1-methyl-1H-pyrazol-4...)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50583945(CHEMBL5080861)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM324337(5-(tert-butyl)-N-(2- (2-((1- methyl-1H-pyrazol-4- ...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50583937(CHEMBL5091935)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50583932(CHEMBL5073223)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50583950(CHEMBL5094998)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50583948(CHEMBL5081318)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50369724(HM71224 | Ly3337641 | Poseltinib)
Affinity DataIC50:  1nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50553436(CHEMBL4744041)
Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged BTK expressed in baculovirus infected Sf21 insect cells using fluorescein-labeled ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50553436(CHEMBL4744041)
Affinity DataIC50:  1nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50583930(CHEMBL5069979)
Affinity DataIC50:  1nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50194720(CHEMBL3900554)
Affinity DataIC50:  1nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50459553(CHEMBL4209441)
Affinity DataIC50: <1nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50244495(CHEMBL4066176)
Affinity DataIC50: <1nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50557487(Tolebrutinib)
Affinity DataIC50:  1nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50161162(AVL-292 | CC-292 | Spebrutinib | US10596172, Compo...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50583934(CHEMBL5087083)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50583949(CHEMBL5075191)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM324348(5-(tert-butyl)-N-(2- (2-((1-methyl-1H- pyrazol-4- ...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50583931(CHEMBL5086077)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50583936(CHEMBL5090623)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50553428(CHEMBL4797536)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged BTK expressed in baculovirus infected Sf21 insect cells using fluorescein-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50553424(CHEMBL4788285)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged BTK expressed in baculovirus infected Sf21 insect cells using fluorescein-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50553433(CHEMBL4760128)
Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged BTK expressed in baculovirus infected Sf21 insect cells using fluorescein-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50553432(CHEMBL4749757)
Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged BTK expressed in baculovirus infected Sf21 insect cells using fluorescein-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50553430(CHEMBL4792826)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged BTK expressed in baculovirus infected Sf21 insect cells using fluorescein-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM324342(5-(tert-butyl)-4-methyl- N-(2-(2-((1-methyl-1H- py...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50583943(CHEMBL5083788)
Affinity DataIC50:  3nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50553421(CHEMBL4740150)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged BTK expressed in baculovirus infected Sf21 insect cells using fluorescein-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50583951(CHEMBL5073995)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50583940(CHEMBL5093755)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50553417(CHEMBL4756023)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged BTK expressed in baculovirus infected Sf21 insect cells using fluorescein-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM291522(1-(4-(((6-amino-5-(4-phenoxyphenyl)pyrimidin-4-yl)...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
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