Compile Data Set for Download or QSAR
maximum 50k data
Found 151 with Last Name = 'tischler' and Initial = 'm'
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4560(4-Phenylamino-3-quinolinecarbonitrile deriv. 31i |...)
Affinity DataIC50:  0.640nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4557(4-Phenylamino-3-quinolinecarbonitrile deriv. 31f |...)
Affinity DataIC50:  0.760nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4553(4-Phenylamino-3-quinolinecarbonitrile deriv. 31b |...)
Affinity DataIC50:  0.770nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4543(4-Phenylamino-3-quinolinecarbonitrile deriv. 2c | ...)
Affinity DataIC50:  0.800nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4544(4-Phenylamino-3-quinolinecarbonitrile deriv. 2d | ...)
Affinity DataIC50:  0.950nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4547(4-Phenylamino-3-quinolinecarbonitrile deriv. 2g | ...)
Affinity DataIC50:  1.10nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4556(4-Phenylamino-3-quinolinecarbonitrile deriv. 31e |...)
Affinity DataIC50:  1.10nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4555(4-Phenylamino-3-quinolinecarbonitrile deriv. 31d |...)
Affinity DataIC50:  1.10nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  1.20nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4559(4-Phenylamino-3-quinolinecarbonitrile deriv. 31h |...)
Affinity DataIC50:  1.20nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4545(4-Phenylamino-3-quinolinecarbonitrile deriv. 2e | ...)
Affinity DataIC50:  1.20nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4550(4-Phenylamino 3-quinolinecarbonitrile deriv. 27 | ...)
Affinity DataIC50:  1.30nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4554(4-Phenylamino-3-quinolinecarbonitrile deriv. 31c |...)
Affinity DataIC50:  1.40nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4558(4-Phenylamino-3-quinolinecarbonitrile deriv. 31g |...)
Affinity DataIC50:  1.40nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4542(4-Phenylamino-3-quinolinecarbonitrile deriv. 2b | ...)
Affinity DataIC50:  1.60nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4546(4-Phenylamino-3-quinolinecarbonitrile deriv. 2f | ...)
Affinity DataIC50:  1.70nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4562(4-Phenylamino-3-quinolinecarbonitrile deriv. 31k |...)
Affinity DataIC50:  1.90nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4563(4-Phenylamino-3-quinolinecarbonitrile deriv. 31l |...)
Affinity DataIC50:  2.10nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4549(4-Phenylamino 3-quinolinecarbonitrile deriv. 26 | ...)
Affinity DataIC50:  2.30nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4565(4-Phenylamino-3-quinolinecarbonitrile deriv. 31n |...)
Affinity DataIC50:  2.30nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4551(4-Phenylamino-3-quinolinecarbonitrile deriv. 28 | ...)
Affinity DataIC50:  2.5nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM21034((1R,3R,5S,6S,18S)-6-hydroxy-18-(methoxymethyl)-1,5...)
Affinity DataIC50:  2.70nMpH: 7.5 T: 2°CAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4534(4-Phenylamino-3-quinolinecarbonitrile deriv. 1l | ...)
Affinity DataIC50:  2.90nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4564(4-Phenylamino-3-quinolinecarbonitrile deriv. 31m |...)
Affinity DataIC50:  3nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4530(4-Phenylamino-3-quinolinecarbonitrile deriv. 1h | ...)
Affinity DataIC50:  3nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4520(4-Phenylamino-3-quinolinecarbonitrile deriv. 25 | ...)
Affinity DataIC50:  3.80nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4531(4-Phenylamino-3-quinolinecarbonitrile deriv. 1i | ...)
Affinity DataIC50:  4nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4525(4-Phenylamino-3-quinolinecarbonitrile deriv. 1c | ...)
Affinity DataIC50:  4.30nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4536(4-Phenylamino-3-quinolinecarbonitrile deriv. 1n | ...)
Affinity DataIC50:  4.60nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM21042((2R,3S,6E,14S,15S,17R)-6-({[2-(dimethylamino)ethyl...)
Affinity DataIC50:  5nMAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4515(4-Phenylamino-3-quinolinecarbonitrile deriv. 1k | ...)
Affinity DataIC50:  6.20nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM21036((2R,3S,6Z,14S,15S,17R)-6-({[3-(dimethylamino)propy...)
Affinity DataIC50:  6.40nMpH: 7.5 T: 2°CAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM21036((2R,3S,6Z,14S,15S,17R)-6-({[3-(dimethylamino)propy...)
Affinity DataIC50:  8nMpH: 7.5 T: 2°CAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM21041((2R,3S,6E,14S,15S,17R)-6-({[2-(dimethylamino)ethyl...)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4561(4-Phenylamino-3-quinolinecarbonitrile deriv. 31j |...)
Affinity DataIC50:  9.30nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM21039((2R,3S,6Z,14S,15S,17R)-6-({tert-butyl[2-(dimethyla...)
Affinity DataIC50:  9.60nMpH: 7.5 T: 2°CAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM21047((2R,3S,6E,14S,15S,17R)-8,14-dihydroxy-3-(methoxyme...)
Affinity DataIC50:  10nMAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4524(4-Phenylamino-3-quinolinecarbonitrile deriv. 1b | ...)
Affinity DataIC50:  10nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM21036((2R,3S,6Z,14S,15S,17R)-6-({[3-(dimethylamino)propy...)
Affinity DataIC50:  11nMpH: 7.5 T: 2°CAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM21043((2R,3S,6E,14S,15S,17R)-6-({[3-(dimethylamino)propy...)
Affinity DataIC50:  12nMAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM21036((2R,3S,6Z,14S,15S,17R)-6-({[3-(dimethylamino)propy...)
Affinity DataIC50:  13nMpH: 7.5 T: 2°CAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM21049((2R,3S,6E,14S,15S,17R)-8,14-dihydroxy-3-(methoxyme...)
Affinity DataIC50:  15nMAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM21046((2R,3S,6E,14S,15S,17R)-6-({bis[3-(dimethylamino)pr...)
Affinity DataIC50:  22nMAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM21048((2R,3S,6E,14S,15S,17R)-8,14-dihydroxy-3-(methoxyme...)
Affinity DataIC50:  24nMAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM21045((2R,3S,6E,14S,15S,17R)-6-({[2-(diethylamino)ethyl]...)
Affinity DataIC50:  24nMAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4548(4-Phenylamino-3-quinolinecarbonitrile deriv. 18 | ...)
Affinity DataIC50:  28nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM4492(4-[(2,4-Dichlorophenyl)amino]-6,7-dimethoxy-3-quin...)
Affinity DataIC50:  30nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM21065(17-Hydroxywortmannin, S25 | methyl 1-{[(2R,3S,6E,1...)
Affinity DataIC50:  31nMAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM21066(1-{[(2R,3S,6E,14S,15S,17R)-17-(acetyloxy)-8,14-dih...)
Affinity DataIC50:  33nMAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM21068((2R,3S,6E,14S,15S,17R)-8,14-dihydroxy-3-(methoxyme...)
Affinity DataIC50:  37nMAssay Description:Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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