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Found 67 with Last Name = 'tkalcevic' and Initial = 'gt'
TargetEstrogen receptor beta(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  0.354nMAssay Description:Inhibition of estradiol binding to estrogen receptorMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM19441(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of estradiol binding to estrogen receptorMore data for this Ligand-Target Pair
TargetSmoothened homolog(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50249522(2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(me...)
Affinity DataIC50:  5nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells using human recombinant SHH assessed as effect on SMO/SHH transient transcriptional activation after 20 hr...More data for this Ligand-Target Pair
TargetSmoothened homolog(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50385635(CHEMBL2043437)
Affinity DataIC50:  5nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells using human recombinant SHH assessed as effect on SMO/SHH transient transcriptional activation after 20 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50385642(CHEMBL2043435)
Affinity DataIC50:  5nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells using human recombinant SHH assessed as effect on SMO/SHH transient transcriptional activation after 20 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50385637(CHEMBL2043430)
Affinity DataIC50:  5nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells using human recombinant SHH assessed as effect on SMO/SHH transient transcriptional activation after 20 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117663(CHEMBL3613707)
Affinity DataIC50:  6nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117662(CHEMBL3613706)
Affinity DataIC50:  6nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117662(CHEMBL3613706)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117663(CHEMBL3613707)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50471710(CHEMBL317748)
Affinity DataIC50:  9.80nMAssay Description:Inhibition of estradiol binding to estrogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM20606((5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phe...)
Affinity DataIC50:  11nMAssay Description:Inhibition of estradiol binding to estrogen receptorMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM20606((5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phe...)
Affinity DataIC50:  11nMAssay Description:Inhibition of estradiol binding to estrogen receptorMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50471711(CHEMBL98892)
Affinity DataIC50:  11nMAssay Description:Inhibition of estradiol binding to estrogen receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50385643(CHEMBL2043436)
Affinity DataIC50:  20nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells using human recombinant SHH assessed as effect on SMO/SHH transient transcriptional activation after 20 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50385641(CHEMBL2043434)
Affinity DataIC50:  35nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells using human recombinant SHH assessed as effect on SMO/SHH transient transcriptional activation after 20 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50065941(1-{2-[4-(6-Methoxy-2-phenyl-3,4-dihydro-naphthalen...)
Affinity DataIC50:  41nMAssay Description:Inhibition of estradiol binding to estrogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50385638(CHEMBL2043432)
Affinity DataIC50:  43nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells using human recombinant SHH assessed as effect on SMO/SHH transient transcriptional activation after 20 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50385640(CHEMBL2043433)
Affinity DataIC50:  45nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells using human recombinant SHH assessed as effect on SMO/SHH transient transcriptional activation after 20 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50471707(CHEMBL98116)
Affinity DataIC50:  47nMAssay Description:Inhibition of estradiol binding to estrogen receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50117668(CHEMBL3613712)
Affinity DataIC50:  63nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117668(CHEMBL3613712)
Affinity DataIC50:  63nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50385644(CHEMBL2043438)
Affinity DataIC50:  72nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells using human recombinant SHH assessed as effect on SMO/SHH transient transcriptional activation after 20 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117667(CHEMBL3613711)
Affinity DataIC50:  72nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117667(CHEMBL3613711)
Affinity DataIC50:  79nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50385639(CHEMBL2043431)
Affinity DataIC50:  88nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells using human recombinant SHH assessed as effect on SMO/SHH transient transcriptional activation after 20 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117665(CHEMBL3613709)
Affinity DataIC50:  92nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117665(CHEMBL3613709)
Affinity DataIC50:  100nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50385636(CHEMBL2043429)
Affinity DataIC50:  103nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells using human recombinant SHH assessed as effect on SMO/SHH transient transcriptional activation after 20 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50471709(CHEMBL421389)
Affinity DataIC50:  132nMAssay Description:Inhibition of estradiol binding to estrogen receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50385645(CHEMBL2043439)
Affinity DataIC50:  191nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells using human recombinant SHH assessed as effect on SMO/SHH transient transcriptional activation after 20 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117665(CHEMBL3613709)
Affinity DataIC50:  204nMAssay Description:Inhibition of human MGAT3 expressed in HEK293 cells assessed as effect on incorporation of [1,3-14C] glycerol into TAG by TLC method in presence of D...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117665(CHEMBL3613709)
Affinity DataIC50:  205nMAssay Description:Inhibition of human MGAT3 expressed in HEK293 cells assessed as effect on incorporation of [1,3-14C] glycerol into TAG by TLC method in presence of D...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50471708(CHEMBL100303)
Affinity DataIC50:  270nMAssay Description:Inhibition of estradiol binding to estrogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117666(CHEMBL3613710)
Affinity DataIC50:  365nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117668(CHEMBL3613712)
Affinity DataIC50:  389nMAssay Description:Inhibition of human MGAT3 expressed in HEK293 cells assessed as effect on incorporation of [1,3-14C] glycerol into TAG by TLC method in presence of D...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117668(CHEMBL3613712)
Affinity DataIC50:  394nMAssay Description:Inhibition of human MGAT3 expressed in HEK293 cells assessed as effect on incorporation of [1,3-14C] glycerol into TAG by TLC method in presence of D...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117666(CHEMBL3613710)
Affinity DataIC50:  398nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117664(CHEMBL3613708)
Affinity DataIC50:  597nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117664(CHEMBL3613708)
Affinity DataIC50:  631nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117659(CHEMBL3613703)
Affinity DataIC50:  631nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117659(CHEMBL3613703)
Affinity DataIC50:  682nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117667(CHEMBL3613711)
Affinity DataIC50:  760nMAssay Description:Inhibition of human MGAT3 expressed in HEK293 cells assessed as effect on incorporation of [1,3-14C] glycerol into TAG by TLC method in presence of D...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117667(CHEMBL3613711)
Affinity DataIC50:  794nMAssay Description:Inhibition of human MGAT3 expressed in HEK293 cells assessed as effect on incorporation of [1,3-14C] glycerol into TAG by TLC method in presence of D...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117660(CHEMBL3613704)
Affinity DataIC50:  2.51E+3nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117660(CHEMBL3613704)
Affinity DataIC50:  2.74E+3nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117661(CHEMBL3613705)
Affinity DataIC50:  3.84E+3nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117661(CHEMBL3613705)
Affinity DataIC50:  3.98E+3nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50117665(CHEMBL3613709)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of PPARgamma (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117665(CHEMBL3613709)
Affinity DataIC50:  1.48E+4nMAssay Description:Inhibition of MGAT1 (unknown origin) assessed as effect on incorporation of [1-14C]decanoyl moiety into DAG using [1-14C]decanoyl-CoA and 2-oleoylgly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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