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Found 174 with Last Name = 'tobin' and Initial = 'jf'
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426487(CHEMBL2322708)
Affinity DataIC50:  2nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295399((2R)-1-(2-Chloro-4-(difluoromethoxy)phenylsulfonyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295399((2R)-1-(2-Chloro-4-(difluoromethoxy)phenylsulfonyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cells in presence of 10 % (v/v) human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295401((2R)-1-(2-Chloro-4-(2-methoxyethoxy)phenylsulfonyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295402((2R)-2-(3-Chloro-4-(4-(4-fluoro-2-(trifluoromethyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295402((2R)-2-(3-Chloro-4-(4-(4-fluoro-2-(trifluoromethyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cells in presence of 10 % (v/v) human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295403((2R)-3-Chloro-4-(4-(4-fluoro-2-(trifluoromethyl)ph...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50295370((2R)-3-Chloro-4-({(2R)-4-[4-fluoro-2-(trifluoromet...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295370((2R)-3-Chloro-4-({(2R)-4-[4-fluoro-2-(trifluoromet...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50426479(CHEMBL2323023)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50426480(CHEMBL2323022)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50426478(CHEMBL2323021)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50426482(CHEMBL2323019)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50426483(CHEMBL2323018)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50426484(CHEMBL2323017)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50426487(CHEMBL2322708)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50426488(CHEMBL2322707)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50426489(CHEMBL2322706)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50426475(CHEMBL2322705)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50426475(CHEMBL2322705)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50426479(CHEMBL2323023)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50426480(CHEMBL2323022)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50426478(CHEMBL2323021)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50426482(CHEMBL2323019)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50426483(CHEMBL2323018)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50426484(CHEMBL2323017)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50426487(CHEMBL2322708)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50426488(CHEMBL2322707)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50426489(CHEMBL2322706)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50426475(CHEMBL2322705)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50426475(CHEMBL2322705)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426479(CHEMBL2323023)
Affinity DataIC50:  10nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426478(CHEMBL2323021)
Affinity DataIC50:  10nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426488(CHEMBL2322707)
Affinity DataIC50:  10nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426489(CHEMBL2322706)
Affinity DataIC50:  10nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50295369((2R)-4-(4-(4-Fluoro-2-(trifluoromethyl)phenyl)-2-m...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295370((2R)-3-Chloro-4-({(2R)-4-[4-fluoro-2-(trifluoromet...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cells in presence of 10 % (v/v) human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295375((2R)-4-(4-(4-Fluoro-2-(trifluoromethyl)phenyl)-2-m...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50295377((2R)-1-(4-Bromo-2-chlorophenylsulfonyl)-4-(4-fluor...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295377((2R)-1-(4-Bromo-2-chlorophenylsulfonyl)-4-(4-fluor...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295377((2R)-1-(4-Bromo-2-chlorophenylsulfonyl)-4-(4-fluor...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cells in presence of 10 % (v/v) human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295378((2R)-3-Chloro-4-(4-(4-fluoro-2-(trifluoromethyl)ph...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295378((2R)-3-Chloro-4-(4-(4-fluoro-2-(trifluoromethyl)ph...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cells in presence of 10 % (v/v) human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295379((2R)-1-[(2-Chloro-4-pyrrolidin-1-ylphenyl)sulfonyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cells in presence of 10 % (v/v) human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295381((2R)-1-{[2-Chloro-4-(4-fluoropiperidin-1-yl)phenyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cells in presence of 10 % (v/v) human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295383((2R)-1-[3-Chloro-4-({(2R)-4-[4-fluoro-2-(trifluoro...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295383((2R)-1-[3-Chloro-4-({(2R)-4-[4-fluoro-2-(trifluoro...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cells in presence of 10 % (v/v) human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50295384((2R)-1-(3-Chloro-4-(2-fluoro-4-(4-fluoro-2-(triflu...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295384((2R)-1-(3-Chloro-4-(2-fluoro-4-(4-fluoro-2-(triflu...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50295385((2R)-1-(3-Chloro-4-(4-(4-fluoro-2-(trifluoromethyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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