TargetRibonucleoside-diphosphate reductase large subunit/subunit M2 B(Homo sapiens (Human))
University Of Camerino
Curated by ChEMBL
University Of Camerino
Curated by ChEMBL
Affinity DataKi: 4.00E+5nMAssay Description:Competitive inhibition of human recombinant ribonucleotide reductase in presence of varying levels of ATP by Dixon plotMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Displacement of [3H]paroxetine from Serotonin transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Inhibition of human FPP synthase expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Inhibition of human HDAC-6 using RHKK(Ac) as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 9.03nMAssay Description:Inhibition of human FPP synthase expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 16.1nMAssay Description:Inhibition of human FPP synthase expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 28.1nMAssay Description:Inhibition of human FPP synthase expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of human HDAC-6 using RHKK(Ac) as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Displacement of GM-FTC from Hsp90-alpha (unknown origin) after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Displacement of GM-FTC from Hsp90-alpha (unknown origin) after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Displacement of GM-FTC from Hsp90-alpha (unknown origin) after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Displacement of GM-FTC from Hsp90-alpha (unknown origin) after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Displacement of GM-FTC from Hsp90-alpha (unknown origin) after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Displacement of GM-FTC from Hsp90-alpha (unknown origin) after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Displacement of GM-FTC from Hsp90-alpha (unknown origin) after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Displacement of GM-FTC from Hsp90-alpha (unknown origin) after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 118nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Displacement of GM-FTC from Hsp90-alpha (unknown origin) after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 243nMAssay Description:Inhibition of human HDAC-8 using RHK(Ac)K(Ac) as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 258nMAssay Description:Inhibition of human HDAC-1 using RHKK(Ac) as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 276nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Displacement of [3H]paroxetine from Serotonin transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 344nMAssay Description:Inhibition of human HDAC-7 using RHKK(Ac) as substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of human HDAC-3/NCOR-2 using RHKK(Ac) as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 362nMAssay Description:Inhibition of human HDAC-11 using RHKK(Ac) as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 378nMAssay Description:Inhibition of human HDAC-5 using RHKK(Ac) as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 388nMAssay Description:Inhibition of human FPP synthase expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 456nMAssay Description:Inhibition of human HDAC-10 using RHKK(Ac) as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 493nMAssay Description:Inhibition of human HDAC-4 using RHKK(Ac) as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 521nMAssay Description:Inhibition of human HDAC-11 using RHKK(Ac) as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant HDAC1 using modified Boc-Lys(Ac)-AMC MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant HDAC1 using modified Boc-Lys(Ac)-AMC MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 883nMAssay Description:Inhibition of human FPP synthase expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
Affinity DataIC50: 886nMAssay Description:Inhibition of human HDAC-10 using RHKK(Ac) as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant HDAC1 using modified Boc-Lys(Ac)-AMC MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 921nMAssay Description:Inhibition of human HDAC-2 using RHKK(Ac) as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.13E+3nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of GM-FTC from Hsp90-alpha (unknown origin) after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant HDAC6 using Z-MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair