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Found 90 with Last Name = 'travelli' and Initial = 'c'
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM81395(APO-866)
Affinity DataKi:  0.300nMAssay Description:Noncompetitive inhibition of NAMPT (unknown origin)More data for this Ligand-Target Pair
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50439676(CHEMBL2417796)
Affinity DataIC50:  0.230nMAssay Description:Inhibition of NAMPT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50347432(CHEMBL1801863)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of NAMPT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50347433(CHEMBL1801864)
Affinity DataIC50:  0.450nMAssay Description:Inhibition of NAMPT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50439675(CHEMBL2417788 | US11279687, Compound 196)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of NAMPT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50439678(CHEMBL2417789)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of recombinant his-tagged NAMPT (unknown origin) expressed in Escherichia coli after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM81395(APO-866)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50439677(CHEMBL2417790 | US9169209, Table 3, Compound 55)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant his-tagged NAMPT (unknown origin) expressed in Escherichia coli after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50236217(CHEMBL4061448)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50515548(CHEMBL4458472)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50236220(CHEMBL4074848)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM81395(APO-866)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50236217(CHEMBL4061448)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of NAMPT in human Jurkat T cells assessed as reduction in NAD levelsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50439680(CHEMBL2417798)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of recombinant his-tagged NAMPT (unknown origin) expressed in Escherichia coli after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50439679(CHEMBL2417799)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of recombinant his-tagged NAMPT (unknown origin) expressed in Escherichia coli after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50236220(CHEMBL4074848)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of NAMPT in human Jurkat T cells assessed as reduction in NAD levelsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50126143(Epacadostat | INCB-024360)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human A375 cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50236219(CHEMBL4066091)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of NAMPT in human Jurkat T cells assessed as reduction in NAD levelsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50236219(CHEMBL4066091)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50514760(CHEMBL4448402)
Affinity DataIC50:  9.30nMAssay Description:Inhibition of mouse IDO1 transfected in P815 cells assessed as reduction in L-Kyn level measured after 16 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50514753(CHEMBL4557994)
Affinity DataIC50:  13nMAssay Description:Inhibition of mouse IDO1 transfected in P815 cells assessed as reduction in L-Kyn level measured after 16 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50514753(CHEMBL4557994)
Affinity DataIC50:  14nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human LXF-289 cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50515544(CHEMBL4535593)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50236221(CHEMBL4078882)
Affinity DataIC50:  16nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50514753(CHEMBL4557994)
Affinity DataIC50:  16nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human A375 cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50515540(CHEMBL4470375)
Affinity DataIC50:  17nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50514759(CHEMBL4571131)
Affinity DataIC50:  19nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human A375 cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50515543(CHEMBL4464821)
Affinity DataIC50:  21nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50514753(CHEMBL4557994)
Affinity DataIC50:  21nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human MCF7 cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50515552(CHEMBL4469394)
Affinity DataIC50:  25nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50236223(CHEMBL4083606)
Affinity DataIC50:  25nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50515551(CHEMBL4446772)
Affinity DataIC50:  25nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50515556(CHEMBL4555764)
Affinity DataIC50:  29nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50236222(CHEMBL4101611)
Affinity DataIC50:  31nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50236224(CHEMBL4088492)
Affinity DataIC50:  32nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50515541(CHEMBL4590810)
Affinity DataIC50:  39nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50515546(CHEMBL4577703)
Affinity DataIC50:  42nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50515545(CHEMBL4440197)
Affinity DataIC50:  42nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50515547(CHEMBL4444551)
Affinity DataIC50:  43nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50514753(CHEMBL4557994)
Affinity DataIC50:  43nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HepG2 cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50236216(CHEMBL4064240)
Affinity DataIC50:  47nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50515542(CHEMBL4569066)
Affinity DataIC50:  50nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50236218(CHEMBL4094769)
Affinity DataIC50:  50nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50514753(CHEMBL4557994)
Affinity DataIC50:  64nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50514760(CHEMBL4448402)
Affinity DataIC50:  72nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50514760(CHEMBL4448402)
Affinity DataIC50:  72nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human A375 cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50515553(CHEMBL4567518)
Affinity DataIC50:  74nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50514760(CHEMBL4448402)
Affinity DataIC50:  83nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human MCF7 cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50515550(CHEMBL4462010)
Affinity DataIC50:  88nMAssay Description:Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50514752(CHEMBL4458549)
Affinity DataIC50:  90nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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