Found 73 with Last Name = 'tropak' and Initial = 'mb' 
Affinity DataKi: 0.0700nMpH: 7.0Assay Description:Fluorescene-based assay using beta-glucocerebrosidase.More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMpH: 5.5Assay Description:Fluorescene-based assay using beta-glucocerebrosidase.More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by Dixon an...More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by Dixon an...More data for this Ligand-Target Pair
Affinity DataKi: 3nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by Dixon an...More data for this Ligand-Target Pair
Affinity DataKi: 4nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by Dixon an...More data for this Ligand-Target Pair
Affinity DataKi: 4.40nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by Dixon an...More data for this Ligand-Target Pair
Affinity DataKi: 5nMpH: 7.0Assay Description:Fluorescene-based assay using beta-glucocerebrosidase.More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 6nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by Dixon an...More data for this Ligand-Target Pair
Affinity DataKi: 12nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by Dixon an...More data for this Ligand-Target Pair
Affinity DataKi: 18nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by Dixon an...More data for this Ligand-Target Pair
Affinity DataKi: 19nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by Dixon an...More data for this Ligand-Target Pair
Affinity DataKi: 23nMpH: 5.5Assay Description:Fluorescene-based assay using beta-glucocerebrosidase.More data for this Ligand-Target Pair
Affinity DataKi: 29nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
Affinity DataKi: 30nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
Affinity DataKi: 76nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
Affinity DataKi: 100nMpH: 5.5Assay Description:Fluorescene-based assay using beta-glucocerebrosidase.More data for this Ligand-Target Pair
Affinity DataKi: 110nMpH: 7.0Assay Description:Fluorescene-based assay using beta-glucocerebrosidase.More data for this Ligand-Target Pair
Affinity DataKi: 180nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
Affinity DataKi: 200nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
Affinity DataKi: 210nMpH: 7.0Assay Description:Fluorescene-based assay using beta-glucocerebrosidase.More data for this Ligand-Target Pair
Affinity DataKi: 250nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
Affinity DataKi: 450nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
Affinity DataKi: 600nMpH: 5.5Assay Description:Fluorescene-based assay using beta-glucocerebrosidase.More data for this Ligand-Target Pair
Affinity DataKi: 610nMpH: 5.5Assay Description:Fluorescene-based assay using beta-glucocerebrosidase.More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMpH: 7.0Assay Description:Fluorescene-based assay using beta-glucocerebrosidase.More data for this Ligand-Target Pair
Affinity DataKi: 2.70E+3nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
Affinity DataKi: 2.80E+3nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Research Institute, Hospital For Sick Children
Research Institute, Hospital For Sick Children
Affinity DataIC50: 600nMT: 2°CAssay Description:Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.More data for this Ligand-Target Pair
TargetCytosolic beta-glucosidase(Homo sapiens (Human))
University Of British Columbia
Curated by ChEMBL
University Of British Columbia
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human cytosolic beta-glucosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by fluorimetric analysisMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Research Institute, Hospital For Sick Children
Research Institute, Hospital For Sick Children
Affinity DataIC50: 3.10E+3nMpH: 7.0Assay Description:Inhibition of human placental HexA using MUGS substrate incubated for 1 to 2 hrs at pH 7.0 by spectrofluorometryMore data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+3nMpH: 7.0Assay Description:Inhibition of human placental HexB using MUGS substrate incubated for 1 to 2 hrs at pH 7.0 by spectrofluorometryMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Research Institute, Hospital For Sick Children
Research Institute, Hospital For Sick Children
Affinity DataIC50: 4.60E+3nMT: 2°CAssay Description:Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.More data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+3nMpH: 5.5 T: 2°CAssay Description:Beta-glucocerebrosidase (GCase) activity was measured by release of 4-methylumbelliferyl fluorophore from MUClc.More data for this Ligand-Target Pair
Affinity DataIC50: 7.80E+3nMpH: 5.5 T: 2°CAssay Description:Beta-glucocerebrosidase (GCase) activity was measured by release of 4-methylumbelliferyl fluorophore from MUClc.More data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Research Institute, Hospital For Sick Children
Research Institute, Hospital For Sick Children
Affinity DataIC50: 8.50E+3nMpH: 4.5Assay Description:Inhibition of HexA alpha G269S mutant in ATSD patient fibroblasts using MUGS substrate incubated for 1 to 2 hrs at pH 4.5 by spectrofluorometryMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Research Institute, Hospital For Sick Children
Research Institute, Hospital For Sick Children
Affinity DataIC50: 8.90E+3nMpH: 4.5Assay Description:Inhibition of human placental HexA using MUGS substrate incubated for 1 to 2 hrs at pH 4.5 by spectrofluorometryMore data for this Ligand-Target Pair
Affinity DataIC50: 9.10E+3nMpH: 4.5Assay Description:Inhibition of human placental HexB using MUGS substrate incubated for 1 to 2 hrs at pH 4.5 by spectrofluorometryMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Research Institute, Hospital For Sick Children
Research Institute, Hospital For Sick Children
Affinity DataIC50: 1.10E+4nMpH: 7.0Assay Description:Inhibition of human placental HexA using MUGS substrate incubated for 1 to 2 hrs at pH 7.0 by spectrofluorometryMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Research Institute, Hospital For Sick Children
Research Institute, Hospital For Sick Children
Affinity DataIC50: 1.40E+4nMpH: 4.5Assay Description:Inhibition of HexA in normal human fibroblasts using MUGS substrate incubated for 1 to 2 hrs at pH 4.5 by spectrofluorometryMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Research Institute, Hospital For Sick Children
Research Institute, Hospital For Sick Children
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of beta-N-acetylhexosaminidase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMpH: 7.0Assay Description:Inhibition of human placental HexB using MUGS substrate incubated for 1 to 2 hrs at pH 7.0 by spectrofluorometryMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Research Institute, Hospital For Sick Children
Research Institute, Hospital For Sick Children
Affinity DataIC50: 1.60E+4nMT: 2°CAssay Description:Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.More data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Research Institute, Hospital For Sick Children
Research Institute, Hospital For Sick Children
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Research Institute, Hospital For Sick Children
Research Institute, Hospital For Sick Children
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Research Institute, Hospital For Sick Children
Research Institute, Hospital For Sick Children
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Research Institute, Hospital For Sick Children
Research Institute, Hospital For Sick Children
Affinity DataIC50: 1.80E+4nMT: 2°CAssay Description:Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+4nMpH: 5.5 T: 2°CAssay Description:Beta-glucocerebrosidase (GCase) activity was measured by release of 4-methylumbelliferyl fluorophore from MUClc.More data for this Ligand-Target Pair
