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Found 202 with Last Name = 'upeslacis' and Initial = 'j'
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143640(4-({5-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-napht...)
Affinity DataIC50:  2.70nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143634(4-{[5-(4-Bromo-phenoxymethyl)-naphthalen-2-ylamino...)
Affinity DataIC50:  2.80nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143650(4-{[5-(3-Chloro-phenoxymethyl)-naphthalen-2-ylamin...)
Affinity DataIC50:  3.10nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143617(CHEMBL442168 | N-{5-[2-(8-Chloro-quinolin-2-yl)-vi...)
Affinity DataIC50:  3.20nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143630(CHEMBL299043 | N-{5-[(E)-2-(6-Chloro-quinolin-2-yl...)
Affinity DataIC50:  3.20nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143627(C,C,C-Trifluoro-N-{5-[2-(6-methoxy-quinolin-2-yl)-...)
Affinity DataIC50:  3.40nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143623(CHEMBL299278 | N-{5-[2-(6-Dimethylamino-quinolin-2...)
Affinity DataIC50:  3.70nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143637(CHEMBL56633 | N-{5-[2-(4-Chloro-phenyl)-vinyl]-nap...)
Affinity DataIC50:  4.30nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143633(4-chloro-N-[({5-[(1E)-7-chloroquinolin-2-yl)vinyl]...)
Affinity DataIC50:  4.70nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143616(4-[(5-Phenoxymethyl-naphthalen-2-ylamino)-methyl]-...)
Affinity DataIC50:  4.80nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143621(CHEMBL55390 | N-[5-(3-Chloro-benzyloxy)-naphthalen...)
Affinity DataIC50:  5.10nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143638(CHEMBL57565 | N-[5-(3-Bromo-benzyloxy)-naphthalen-...)
Affinity DataIC50:  6.10nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143628(C,C,C-Trifluoro-N-{5-[2-(6-methyl-quinolin-2-yl)-v...)
Affinity DataIC50:  6.30nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143641(C,C,C-Trifluoro-N-{5-[2-(3-trifluoromethyl-phenyl)...)
Affinity DataIC50:  6.5nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143618(C,C,C-Trifluoro-N-{5-[2-(3-methoxy-phenyl)-vinyl]-...)
Affinity DataIC50:  6.60nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143635(CHEMBL440672 | N-[({5-[(1E)-7-chloroquinolin-2-yl)...)
Affinity DataIC50:  6.70nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143632(CHEMBL56307 | N-{5-[(E)-2-(3-Trifluoromethyl-pheny...)
Affinity DataIC50:  6.90nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143646(4-({5-[(E)-2-(3-Trifluoromethyl-phenyl)-vinyl]-nap...)
Affinity DataIC50:  6.90nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50161879(4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(3...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human epidermal growth factor receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143629(CHEMBL57465 | N-[5-(3-Trifluoromethyl-benzyloxy)-n...)
Affinity DataIC50:  7.40nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143625(C,C,C-Trifluoro-N-(5-styryl-naphthalen-2-yl)-metha...)
Affinity DataIC50:  7.5nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50161879(4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(3...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human epidermal growth factor receptor-2 (HER-2) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143636(4-methyl-N-[({5-[(1E)-7-chloroquinolin-2-yl)vinyl]...)
Affinity DataIC50:  8.30nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143615(C,C,C-Trifluoro-N-[5-(2-quinolin-2-yl-vinyl)-napht...)
Affinity DataIC50:  9.5nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50161948(4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(n...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human epidermal growth factor receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50161903(4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(2...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human epidermal growth factor receptor-2 (HER-2) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143643(CHEMBL56642 | N-{5-[2-(4-Chloro-quinolin-2-yl)-vin...)
Affinity DataIC50:  10.5nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50161903(4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(2...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human epidermal growth factor receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50161956(4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(4...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human epidermal growth factor receptor-2 (HER-2) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143619(C,C,C-Trifluoro-N-[5-(2-naphthalen-2-yl-vinyl)-nap...)
Affinity DataIC50:  15nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50161883(4-Dimethylamino-but-2-enoic acid [4-(1-benzyl-1H-i...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human epidermal growth factor receptor-2 (HER-2) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50161911(4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(n...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human epidermal growth factor receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143626(CHEMBL57617 | N-{5-[2-(7-Chloro-quinolin-2-yl)-vin...)
Affinity DataIC50:  15.1nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143620(CHEMBL52599 | N-[5-(3-Trifluoromethyl-phenoxymethy...)
Affinity DataIC50:  15.2nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143631(CHEMBL57169 | N-[5-(3-Chloro-phenoxymethyl)-naphth...)
Affinity DataIC50:  15.3nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50161926(4-Thiomorpholin-4-yl-but-2-enoic acid [4-(4-benzyl...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human epidermal growth factor receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143645(CHEMBL293304 | N-{5-[(E)-2-(7-Chloro-quinolin-2-yl...)
Affinity DataIC50:  17.4nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50161911(4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(n...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human epidermal growth factor receptor-2 (HER-2) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50161948(4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(n...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human epidermal growth factor receptor-2 (HER-2) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50161955(4-[(2-Hydroxy-ethyl)-methyl-amino]-but-2-enoic aci...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human epidermal growth factor receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50161907(4-Morpholin-4-yl-but-2-enoic acid [4-(4-benzyloxy-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human epidermal growth factor receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143647(CHEMBL56741 | N-[5-(4-Bromo-phenoxymethyl)-naphtha...)
Affinity DataIC50:  21.3nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50161880(4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(f...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human epidermal growth factor receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50161947(4-(1H-Imidazol-4-yl)-but-2-enoic acid [4-(4-benzyl...)
Affinity DataIC50:  24nMAssay Description:Inhibition of human epidermal growth factor receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50161891(4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(4...)
Affinity DataIC50:  24nMAssay Description:Inhibition of human epidermal growth factor receptor-2 (HER-2) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50161940(4-Dimethylamino-but-2-enoic acid [4-(4-benzyloxy-3...)
Affinity DataIC50:  24nMAssay Description:Inhibition of human epidermal growth factor receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50161938(4-Piperidin-1-yl-but-2-enoic acid [4-(4-benzyloxy-...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human epidermal growth factor receptor-2 (HER-2) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50161946(4-Dimethylamino-but-2-enoic acid [4-(1-benzenesulf...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human epidermal growth factor receptor-2 (HER-2) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50161936(4-Azetidin-1-yl-but-2-enoic acid [4-(4-benzyloxy-3...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human epidermal growth factor receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50161955(4-[(2-Hydroxy-ethyl)-methyl-amino]-but-2-enoic aci...)
Affinity DataIC50:  27nMAssay Description:Inhibition of human epidermal growth factor receptor-2 (HER-2) autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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