Affinity DataKi: 0.170nMAssay Description:In vitro binding affinity against substance P (NK-1) receptor in human IM-9 cell using [125I]-BH-SPMore data for this Ligand-Target Pair
Affinity DataKi: 0.990nMAssay Description:In vitro inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Antibacterial activity against Escherichia coli DHFRMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:In vitro binding affinity against substance P (NK-1) receptor in human IM-9 cell using [125I]-BH-SPMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nM Kon: 0.000300M-1s-1 Koff: 1.40E+5s-1Assay Description:Compound was evaluated for the enzyme kinetic data (kon) for binding inhibition against Prolyl Endopeptidase (PEP)More data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:In vitro inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
Affinity DataKi: 3nM Kon: 0.000700M-1s-1 Koff: 2.30E+5s-1Assay Description:Compound was evaluated for the enzyme kinetic data (kon) for binding inhibition against Prolyl Endopeptidase (PEP)More data for this Ligand-Target Pair
Affinity DataKi: 3nM Kon: 0.00200M-1s-1 Koff: 7.00E+5s-1Assay Description:Compound was evaluated for the enzyme kinetic data (kon) for binding inhibition against Prolyl Endopeptidase (PEP)More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Compound was evaluated for binding inhibition against Prolyl Endopeptidase (PEP).More data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:In vitro inhibition of dihydrofolate reductase of Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:In vitro inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:In vitro inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:In vitro inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
Affinity DataKi: 226nMAssay Description:In vitro inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:In vitro inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
Affinity DataKi: 1.22E+3nMAssay Description:In vitro inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity against substance P (NK-1) receptor in human IM-9 cell using [125I]-BH-SPMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at integrin alphaVbeta3 in human A375M cells assessed as cell adhesion to fibrinogen in presence of Mg2+More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at integrin alphavbeta3 in human A375M cells assessed as inhibition of cell adhesion to fibrinogen in presence of Mg2+More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Binding affinity to integrin alpha5beta1More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Antagonist activity at integrin alphavbeta3 in human A375M cells assessed as inhibition of cell adhesion to fibrinogen in presence of Mg2+More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Binding affinity to integrin alpha5beta1More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Binding affinity to integrin alpha5beta1More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal ploy-His-tagged human PI3Kbeta expressed in baculovirus-infected sf21 cells using PI(4,5)P2 as substrate after 15 mins by HT...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Binding affinity to integrin alpha5beta1More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal ploy-His-tagged human PI3Kbeta expressed in baculovirus-infected sf21 cells using PI(4,5)P2 as substrate after 15 mins by HT...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Binding affinity to integrin alpha5beta1More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Binding affinity to integrin alpha5beta1More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Binding affinity to integrin alpha5beta1More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Antagonist activity at integrin alpha5beta1 in human A375M cells assessed as inhibition of cell adhesion to fibronectin in presence of Mg2+ and MK-04...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Binding affinity to integrin alpha5beta1More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Binding affinity to integrin alpha5beta1More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of N-terminal ploy-His-tagged human PI3Kdelta expressed in baculovirus-infected sf9 cells using PI(4,5)P2 as substrate after 15 mins by HT...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Binding affinity to integrin alpha5beta1More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Binding affinity to integrin alpha5beta1More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Binding affinity to integrin alpha5beta1More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal ploy-His-tagged human PI3Kbeta expressed in baculovirus-infected sf21 cells using PI(4,5)P2 as substrate after 15 mins by HT...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue expressed in PTEN-deficient human PC3 cells by chemiluminescence assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at T308 residue expressed in PTEN-deficient human PC3 cells after 2 hrs by Western blot ana...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Binding affinity to integrin alpha5beta1More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human PI3Kbeta-mediated Akt phosphorylation at T308 residue expressed in PTEN-deficient human PC3 cells after 2 hrs by Western blot ana...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal ploy-His-tagged human PI3Kbeta expressed in baculovirus-infected sf21 cells using PI(4,5)P2 as substrate after 15 mins by HT...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Binding affinity to integrin alpha5beta1More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of N-terminal ploy-His-tagged human PI3Kbeta expressed in baculovirus-infected sf21 cells using PI(4,5)P2 as substrate after 15 mins by HT...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of N-terminal ploy-His-tagged human PI3Kbeta expressed in baculovirus-infected sf21 cells using PI(4,5)P2 as substrate after 15 mins by HT...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of N-terminal ploy-His-tagged human PI3Kbeta expressed in baculovirus-infected sf21 cells using PI(4,5)P2 as substrate after 15 mins by HT...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Binding affinity to integrin alpha5beta1More data for this Ligand-Target Pair