Affinity DataIC50: 7.94nMAssay Description:Displacement of [3H]-Ro256981 from human NR2B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 7.94nMAssay Description:Displacement of [3H]-Ro256981 from human NR2B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 7.94nMAssay Description:Displacement of [3H]-Ro256981 from human NR2B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 12.6nMAssay Description:Displacement of [3H]-Ro256981 from human NR2B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 31.6nMAssay Description:Displacement of [3H]-Ro256981 from human NR2B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 39.8nMAssay Description:Displacement of [3H]-Ro256981 from human NR2B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 39.8nMAssay Description:Displacement of [3H]-Ro256981 from human NR2B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 39.8nMAssay Description:Displacement of [3H]-Ro256981 from human NR2B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 79.4nMAssay Description:Displacement of [3H]-Ro256981 from human NR2B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 79.4nMAssay Description:Displacement of [3H]-Ro256981 from human NR2B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 79.4nMAssay Description:Displacement of [3H]-Ro256981 from human NR2B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]-Ro256981 from human NR2B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 251nMAssay Description:Displacement of [3H]-Ro256981 from human NR2B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 398nMAssay Description:Displacement of [3H]-Ro256981 from human NR2B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 398nMAssay Description:Displacement of [3H]-Ro256981 from human NR2B receptorMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 5(Homo sapiens (Human))
Turning Point Therapeutics
Curated by ChEMBL
Turning Point Therapeutics
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Antagonist activity at TRPM5 (unknown origin)More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 5(Homo sapiens (Human))
Turning Point Therapeutics
Curated by ChEMBL
Turning Point Therapeutics
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Antagonist activity at TRPM5 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 631nMAssay Description:Displacement of [3H]-Ro256981 from human NR2B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 794nMAssay Description:Displacement of [3H]-Ro256981 from human NR2B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 794nMAssay Description:Antagonist activity at human alpha1 nAChR in human TE671 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 794nMAssay Description:Displacement of [3H]-Ro256981 from human NR2B receptorMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human alpha3 nAChR in human IMR32 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human alpha1 nAChR in human TE671 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human 5HT3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]-Ro256981 from human NR2B receptorMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human alpha4 nAChR in human IMR32 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.58E+3nMAssay Description:Displacement of [3H]-Ro256981 from human NR2B receptorMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 2.51E+3nMAssay Description:Antagonist activity at human alpha3 nAChR in human IMR32 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.51E+3nMAssay Description:Displacement of [3H]-Ro256981 from human NR2B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
Affinity DataIC50: 4.20E+3nMAssay Description:Binding affinity to alpha1 nAchR expressed in human TE671 cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Ferrara
Curated by ChEMBL
University Of Ferrara
Curated by ChEMBL
Affinity DataIC50: 4.60E+3nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAchR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Binding affinity to alpha1 nAchR expressed in human TE671 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
Affinity DataIC50: 7.80E+3nMAssay Description:Binding affinity to alpha1 nAchR expressed in human TE671 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.94E+3nMAssay Description:Antagonist activity at human 5HT3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]-Ro256981 from human NR2B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]-Ro256981 from human NR2B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]-Ro256981 from human NR2B receptorMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Ferrara
Curated by ChEMBL
University Of Ferrara
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAchR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to alpha1 nAchR expressed in human TE671 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to alpha1 nAchR expressed in human TE671 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to alpha1 nAchR expressed in human TE671 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to alpha1 nAchR expressed in human TE671 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to alpha1 nAchR expressed in human TE671 cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Ferrara
Curated by ChEMBL
University Of Ferrara
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAchR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Ferrara
Curated by ChEMBL
University Of Ferrara
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]-alpha-bungarotoxin from alpha7 nAchR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair