Affinity DataKi: 30nMAssay Description:Catalytic rate constant (Kobs/[I]) of the compound was evaluated against human rhinovirus (HRV) serotype 14 3C Protease (3CP)More data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:The compound was tested for binding affinity of Human Rhinovirus (HRV) 3C Protease.More data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:The compound was tested for binding affinity of Human Rhinovirus (HRV) 3C Protease.More data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:The compound was tested for irreversible inhibition of Human Rhinovirus (HRV) 3C Protease.More data for this Ligand-Target Pair
Affinity DataKi: 1.80E+3nMAssay Description:The compound was tested for binding affinity of Human Rhinovirus (HRV) 3C Protease.More data for this Ligand-Target Pair
Affinity DataKi: 1.80E+3nMAssay Description:The compound was tested for binding affinity of Human Rhinovirus (HRV) 3C Protease.More data for this Ligand-Target Pair
Affinity DataKi: 1.90E+3nMAssay Description:The compound was tested for binding affinity of Human Rhinovirus (HRV) 3C Protease.More data for this Ligand-Target Pair
Affinity DataKi: 9.00E+3nMAssay Description:The compound was tested for binding affinity of Human Rhinovirus (HRV) 3C Protease.More data for this Ligand-Target Pair
Affinity DataKi: 2.50E+4nMAssay Description:The compound was tested for binding affinity of Human Rhinovirus (HRV) 3C Protease.More data for this Ligand-Target Pair
Affinity DataKi: 1.04E+5nMAssay Description:Inhibition of Human Rhinovirus (HRV-14) 3C ProteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of MEK1 by IMAP assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of MEK1 by IMAP assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of MEK1 by IMAP assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Inhibition of MEK1 by IMAP assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Inhibition of MEK1 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of MEK1 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of MEK1 by IMAP assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataIC50: 4.80nMAssay Description:Inhibition of MEK1 by IMAP assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Inhibition of MEK1 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of MEK1 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataIC50: 5.90nMAssay Description:Inhibition of MEK1 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Quanticel Research
Curated by ChEMBL
Celgene Quanticel Research
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of KDM4C (unknown origin) using biotinylated H3K9me3 peptide and alpha-ketoglutarate as substrate pretreated for 1 hr followed by substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of MEK1 by cascade assay methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 8nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit DPP enzymes mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic assay....More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Quanticel Research
Curated by ChEMBL
Celgene Quanticel Research
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of KDM4C (unknown origin) using biotinylated H3K9me3 peptide and alpha-ketoglutarate as substrate pretreated for 1 hr followed by substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair