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Found 44 with Last Name = 'wang' and Initial = 'jb'
TargetNociceptin receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50262295(4-[(4R,7S,10S,13R)-10-(3-{[amino(iminiumyl)methyl]...)
Affinity DataKi:  0.100nMAssay Description:Binding affinity to human NOP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50262291(4-[(3S,6S,9S,17S)-6-(3-{[amino(iminiumyl)methyl]am...)
Affinity DataKi:  0.270nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50262290(4-[(3S,6S,9S,12S,20S)-6-(3-{[amino(iminiumyl)methy...)
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50106479(CHEMBL384755 | FGGFTGARKSARK | H-FGGFTGARKSARK-NH2...)
Affinity DataKi:  0.350nMAssay Description:Binding affinity to human NOP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50262292(CHEMBL507269 | [Asp6,Lys10]N/OFQ(1-13)NH2)
Affinity DataKi:  0.540nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50106479(CHEMBL384755 | FGGFTGARKSARK | H-FGGFTGARKSARK-NH2...)
Affinity DataKi:  0.620nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50106469(CHEMBL269029 | FGGFTCARKCARK | cyclo[Cys6,Cys10]N/...)
Affinity DataKi:  0.830nMAssay Description:Binding affinity to human NOP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50262293(CHEMBL507653 | [D-Asp7,Lys10]N/OFQ(1-13)NH2)
Affinity DataKi:  1.79nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50216982(CHEMBL235239 | UMB-97 | UMB97)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]DAMGO from cloned mu opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50216981(CHEMBL238017 | UMB-95 | UMB95)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]DAMGO from cloned mu opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50216980(CHEMBL401245 | UMB-94 | UMB94)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]DAMGO from cloned mu opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50216980(CHEMBL401245 | UMB-94 | UMB94)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]DPDPE from cloned delta opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50216980(CHEMBL401245 | UMB-94 | UMB94)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]U-69593 from cloned kappa opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50216981(CHEMBL238017 | UMB-95 | UMB95)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]DPDPE from cloned delta opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50216983(CHEMBL392269 | UMB-96 | UMB96)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]DAMGO from cloned mu opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50216981(CHEMBL238017 | UMB-95 | UMB95)
Affinity DataKi:  64nMAssay Description:Displacement of [3H]U-69593 from cloned kappa opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50216983(CHEMBL392269 | UMB-96 | UMB96)
Affinity DataKi:  110nMAssay Description:Displacement of [3H]DPDPE from cloned delta opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50216982(CHEMBL235239 | UMB-97 | UMB97)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]DPDPE from cloned delta opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50216983(CHEMBL392269 | UMB-96 | UMB96)
Affinity DataKi:  170nMAssay Description:Displacement of [3H]U-69593 from cloned kappa opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50216982(CHEMBL235239 | UMB-97 | UMB97)
Affinity DataKi:  230nMAssay Description:Displacement of [3H]U-69593 from cloned kappa opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine 5'-monophosphoramidase HINT1(Rattus norvegicus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50326433(((2R,3R,4S,5R)-5-(2-amino-6-oxo-1H-purin-9(6H)-yl)...)
Affinity DataKd:  6.70E+4nMAssay Description:Binding affinity to mouse HINT1 by fluorescence quenching assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine 5'-monophosphoramidase HINT1(Rattus norvegicus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM22579(AICAR | Aminoimidazole-4-carboxamide ribonucleotid...)
Affinity DataKd:  1.10E+6nMAssay Description:Binding affinity to mouse HINT1 by fluorescence quenching assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine 5'-monophosphoramidase HINT1(Rattus norvegicus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM22579(AICAR | Aminoimidazole-4-carboxamide ribonucleotid...)
Affinity DataKd:  1.20E+6nMAssay Description:Binding affinity to mouse HINT1 by HSQC spectra assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50262290(4-[(3S,6S,9S,12S,20S)-6-(3-{[amino(iminiumyl)methy...)
Affinity DataEC50:  4.12nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50262291(4-[(3S,6S,9S,17S)-6-(3-{[amino(iminiumyl)methyl]am...)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50262292(CHEMBL507269 | [Asp6,Lys10]N/OFQ(1-13)NH2)
Affinity DataEC50:  22.3nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50262293(CHEMBL507653 | [D-Asp7,Lys10]N/OFQ(1-13)NH2)
Affinity DataEC50:  106nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50106479(CHEMBL384755 | FGGFTGARKSARK | H-FGGFTGARKSARK-NH2...)
Affinity DataEC50:  7.82nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50106479(CHEMBL384755 | FGGFTGARKSARK | H-FGGFTGARKSARK-NH2...)
Affinity DataEC50:  0.780nMAssay Description:Agonist activity at human NOP receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50106469(CHEMBL269029 | FGGFTCARKCARK | cyclo[Cys6,Cys10]N/...)
Affinity DataEC50:  31nMAssay Description:Agonist activity at human NOP receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50262295(4-[(4R,7S,10S,13R)-10-(3-{[amino(iminiumyl)methyl]...)
Affinity DataEC50:  0.690nMAssay Description:Agonist activity at human NOP receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50216980(CHEMBL401245 | UMB-94 | UMB94)
Affinity DataEC50:  43nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50216983(CHEMBL392269 | UMB-96 | UMB96)
Affinity DataEC50:  520nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50216981(CHEMBL238017 | UMB-95 | UMB95)
Affinity DataEC50:  210nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50216982(CHEMBL235239 | UMB-97 | UMB97)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50216982(CHEMBL235239 | UMB-97 | UMB97)
Affinity DataEC50:  720nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50216983(CHEMBL392269 | UMB-96 | UMB96)
Affinity DataEC50:  89nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50216980(CHEMBL401245 | UMB-94 | UMB94)
Affinity DataEC50:  240nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50216981(CHEMBL238017 | UMB-95 | UMB95)
Affinity DataEC50:  15nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50216981(CHEMBL238017 | UMB-95 | UMB95)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50216980(CHEMBL401245 | UMB-94 | UMB94)
Affinity DataEC50:  88nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine 5'-monophosphoramidase HINT1(Rattus norvegicus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50326433(((2R,3R,4S,5R)-5-(2-amino-6-oxo-1H-purin-9(6H)-yl)...)
Affinity DataKd:  6.00E+4nMAssay Description:Binding affinity to mouse HINT1 by NMR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50216982(CHEMBL235239 | UMB-97 | UMB97)
Affinity DataEC50:  57nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50216983(CHEMBL392269 | UMB-96 | UMB96)
Affinity DataEC50:  210nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed