Affinity DataKi: 0.100nMAssay Description:Binding affinity to human NOP receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.340nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.350nMAssay Description:Binding affinity to human NOP receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.540nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.620nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.830nMAssay Description:Binding affinity to human NOP receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.79nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Displacement of [3H]DAMGO from cloned mu opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Displacement of [3H]DAMGO from cloned mu opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]DAMGO from cloned mu opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Displacement of [3H]DPDPE from cloned delta opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Displacement of [3H]U-69593 from cloned kappa opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Displacement of [3H]DPDPE from cloned delta opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Displacement of [3H]DAMGO from cloned mu opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 64nMAssay Description:Displacement of [3H]U-69593 from cloned kappa opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Displacement of [3H]DPDPE from cloned delta opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Displacement of [3H]DPDPE from cloned delta opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Displacement of [3H]U-69593 from cloned kappa opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:Displacement of [3H]U-69593 from cloned kappa opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
TargetAdenosine 5'-monophosphoramidase HINT1(Rattus norvegicus)
University Of Maryland
Curated by ChEMBL
University Of Maryland
Curated by ChEMBL
Affinity DataKd: 6.70E+4nMAssay Description:Binding affinity to mouse HINT1 by fluorescence quenching assayMore data for this Ligand-Target Pair
TargetAdenosine 5'-monophosphoramidase HINT1(Rattus norvegicus)
University Of Maryland
Curated by ChEMBL
University Of Maryland
Curated by ChEMBL
Affinity DataKd: 1.10E+6nMAssay Description:Binding affinity to mouse HINT1 by fluorescence quenching assayMore data for this Ligand-Target Pair
TargetAdenosine 5'-monophosphoramidase HINT1(Rattus norvegicus)
University Of Maryland
Curated by ChEMBL
University Of Maryland
Curated by ChEMBL
Affinity DataKd: 1.20E+6nMAssay Description:Binding affinity to mouse HINT1 by HSQC spectra assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4.12nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 1.60nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 22.3nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 106nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 7.82nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 0.780nMAssay Description:Agonist activity at human NOP receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 31nMAssay Description:Agonist activity at human NOP receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.690nMAssay Description:Agonist activity at human NOP receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 43nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 520nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 210nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 720nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 89nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 240nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 15nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 88nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetAdenosine 5'-monophosphoramidase HINT1(Rattus norvegicus)
University Of Maryland
Curated by ChEMBL
University Of Maryland
Curated by ChEMBL
Affinity DataKd: 6.00E+4nMAssay Description:Binding affinity to mouse HINT1 by NMR analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 57nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 210nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair