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Found 57 with Last Name = 'wang' and Initial = 'sz'
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50014757((4-Chloro-phenyl)-(2-chloro-phenyl)-pyridin-3-yl-m...)
Affinity DataIC50:  600nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50485474(CHEMBL1862838 | DNDI1322027)
Affinity DataIC50:  900nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50485473(CHEMBL1863499 | DNDI1336037)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50485466(CHEMBL1863004 | DNDI1335913)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50485471(CHEMBL1863383 | DNDI1335912)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50485476(CHEMBL1863160 | DNDI1294211)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50485475(CHEMBL1863146 | DNDI1336031)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50485468(CHEMBL1863039 | DNDI1467766)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50485467(CHEMBL1863325 | DNDI1574842)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50485470(CHEMBL1863007 | DNDI1342987)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50485469(CHEMBL1863183 | DNDI1268111)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50485472(CHEMBL1863379 | DNDI1330083)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260319(CHEMBL4104534)
Affinity DataIC50:  2.34E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260318(CHEMBL4061404)
Affinity DataIC50:  3.93E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260307(CHEMBL4089550)
Affinity DataIC50:  4.18E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260320(CHEMBL4094380)
Affinity DataIC50:  5.25E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260302(CHEMBL4064304)
Affinity DataIC50:  5.43E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260299(CHEMBL4088294)
Affinity DataIC50:  5.59E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260309(CHEMBL4077866)
Affinity DataIC50:  5.68E+5nMAssay Description:Reactivation of sarin-induced inhibition of human AChE assessed as dissociation constant using acetylthiocholine as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260313(CHEMBL4100639)
Affinity DataIC50:  6.26E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260308(CHEMBL4102122)
Affinity DataIC50:  6.37E+5nMAssay Description:Reactivation of VX-induced inhibition of human AChE assessed as dissociation constant using acetylthiocholine as substrate preincubated for 30 mins f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260310(CHEMBL4064154)
Affinity DataIC50:  6.58E+5nMAssay Description:Reactivation of tabun-induced inhibition of human AChE assessed as dissociation constant using acetylthiocholine as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50035852(HI-6)
Affinity DataIC50:  6.68E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260322(CHEMBL4063109)
Affinity DataIC50:  6.85E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260306(CHEMBL4062826)
Affinity DataIC50:  6.93E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260326(CHEMBL4086639)
Affinity DataIC50:  7.40E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260316(CHEMBL4076907)
Affinity DataIC50:  7.55E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260301(CHEMBL4062487)
Affinity DataIC50:  8.02E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260311(CHEMBL4085722)
Affinity DataIC50:  8.48E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260325(CHEMBL4091945)
Affinity DataIC50:  8.96E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260324(CHEMBL4073838)
Affinity DataIC50:  9.08E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260317(CHEMBL4084189)
Affinity DataIC50:  9.11E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260321(CHEMBL4066891)
Affinity DataIC50:  9.41E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260305(CHEMBL4104406)
Affinity DataIC50:  9.57E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260327(CHEMBL4091001)
Affinity DataIC50:  9.77E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM234367(Pralidoxime (3))
Affinity DataIC50:  9.96E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260304(CHEMBL4060058)
Affinity DataIC50:  1.06E+6nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260314(CHEMBL4065242)
Affinity DataIC50:  1.12E+6nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260315(CHEMBL4092905)
Affinity DataIC50:  1.21E+6nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260303(CHEMBL4068713)
Affinity DataIC50:  1.27E+6nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260312(CHEMBL4100057)
Affinity DataIC50:  1.38E+6nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260323(CHEMBL4080917)
Affinity DataIC50:  1.57E+6nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50005579(CHEMBL139148 | Obidoxime)
Affinity DataIC50:  2.17E+6nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260308(CHEMBL4102122)
Affinity DataKd:  8.90E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260311(CHEMBL4085722)
Affinity DataKd:  5.12E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260309(CHEMBL4077866)
Affinity DataKd:  7.20E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260307(CHEMBL4089550)
Affinity DataKd:  3.80E+4nMAssay Description:Reactivation of tabun-induced inhibition of human AChE assessed as dissociation constant using acetylthiocholine as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260310(CHEMBL4064154)
Affinity DataKd:  5.30E+4nMAssay Description:Reactivation of tabun-induced inhibition of human AChE assessed as dissociation constant using acetylthiocholine as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260307(CHEMBL4089550)
Affinity DataKd:  7.60E+3nMAssay Description:Reactivation of tabun-induced inhibition of human AChE assessed as dissociation constant using acetylthiocholine as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260309(CHEMBL4077866)
Affinity DataKd:  2.04E+5nMAssay Description:Reactivation of sarin-induced inhibition of human AChE assessed as dissociation constant using acetylthiocholine as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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