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Found 29 with Last Name = 'watanabe' and Initial = 'r'
TargetMelatonin receptor type 1B(Homo sapiens (Human))
AchÉ

US Patent
LigandPNGBDBM50035179(Agomelatine | CHEMBL10878 | N-[2-(7-Methoxy-naphth...)
Affinity DataKi:  0.0420nMAssay Description:The binding assay was performed in melatonergic MT1 and MT2 receptors in order to check the receptor affinity for the ligand, i.e., the ability of th...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetMetallothionein-2(Human)
AchÉ

US Patent
LigandPNGBDBM50035179(Agomelatine | CHEMBL10878 | N-[2-(7-Methoxy-naphth...)
Affinity DataKi:  0.0420nMAssay Description:The binding assay was performed in melatonergic MT1 and MT2 receptors in order to check the receptor affinity for the ligand, i.e., the ability of th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelatonin receptor type 1A(Homo sapiens (Human))
AchÉ

US Patent
LigandPNGBDBM50035179(Agomelatine | CHEMBL10878 | N-[2-(7-Methoxy-naphth...)
Affinity DataKi:  0.200nMAssay Description:The binding assay was performed in melatonergic MT1 and MT2 receptors in order to check the receptor affinity for the ligand, i.e., the ability of th...More data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
AchÉ

US Patent
LigandPNGBDBM50035179(Agomelatine | CHEMBL10878 | N-[2-(7-Methoxy-naphth...)
Affinity DataKi:  0.200nMAssay Description:The binding assay was performed in melatonergic MT1 and MT2 receptors in order to check the receptor affinity for the ligand, i.e., the ability of th...More data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
AchÉ

US Patent
LigandPNGBDBM463447(US10781182, Compound IA2-143 | US11091445, Compoun...)
Affinity DataKi:  0.800nMAssay Description:The binding assay was performed in melatonergic MT1 and MT2 receptors in order to check the receptor affinity for the ligand, i.e., the ability of th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetallothionein-2(Human)
AchÉ

US Patent
LigandPNGBDBM463447(US10781182, Compound IA2-143 | US11091445, Compoun...)
Affinity DataKi:  0.800nMAssay Description:The binding assay was performed in melatonergic MT1 and MT2 receptors in order to check the receptor affinity for the ligand, i.e., the ability of th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelatonin receptor type 1A(Homo sapiens (Human))
AchÉ

US Patent
LigandPNGBDBM463444(US10781182, Compound IA2-121 | US11091445, Compoun...)
Affinity DataKi:  0.880nMAssay Description:The binding assay was performed in melatonergic MT1 and MT2 receptors in order to check the receptor affinity for the ligand, i.e., the ability of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelatonin receptor type 1A(Homo sapiens (Human))
AchÉ

US Patent
LigandPNGBDBM463444(US10781182, Compound IA2-121 | US11091445, Compoun...)
Affinity DataKi:  0.880nMAssay Description:The binding assay was performed in melatonergic MT1 and MT2 receptors in order to check the receptor affinity for the ligand, i.e., the ability of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelatonin receptor type 1B(Homo sapiens (Human))
AchÉ

US Patent
LigandPNGBDBM463444(US10781182, Compound IA2-121 | US11091445, Compoun...)
Affinity DataKi:  0.930nMAssay Description:The binding assay was performed in melatonergic MT1 and MT2 receptors in order to check the receptor affinity for the ligand, i.e., the ability of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallothionein-2(Human)
AchÉ

US Patent
LigandPNGBDBM463444(US10781182, Compound IA2-121 | US11091445, Compoun...)
Affinity DataKi:  0.930nMAssay Description:The binding assay was performed in melatonergic MT1 and MT2 receptors in order to check the receptor affinity for the ligand, i.e., the ability of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelatonin receptor type 1A(Homo sapiens (Human))
AchÉ

US Patent
LigandPNGBDBM463443(US10781182, Compound IA2-120 | US11091445, Compoun...)
Affinity DataKi:  1.10nMAssay Description:The binding assay was performed in melatonergic MT1 and MT2 receptors in order to check the receptor affinity for the ligand, i.e., the ability of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelatonin receptor type 1A(Homo sapiens (Human))
AchÉ

US Patent
LigandPNGBDBM463443(US10781182, Compound IA2-120 | US11091445, Compoun...)
Affinity DataKi:  1.10nMAssay Description:The binding assay was performed in melatonergic MT1 and MT2 receptors in order to check the receptor affinity for the ligand, i.e., the ability of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallothionein-2(Human)
AchÉ

US Patent
LigandPNGBDBM463446(US10781182, Compound IA2-142 | US11091445, Compoun...)
Affinity DataKi:  1.60nMAssay Description:The binding assay was performed in melatonergic MT1 and MT2 receptors in order to check the receptor affinity for the ligand, i.e., the ability of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelatonin receptor type 1B(Homo sapiens (Human))
AchÉ

US Patent
LigandPNGBDBM463446(US10781182, Compound IA2-142 | US11091445, Compoun...)
Affinity DataKi:  1.60nMAssay Description:The binding assay was performed in melatonergic MT1 and MT2 receptors in order to check the receptor affinity for the ligand, i.e., the ability of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelatonin receptor type 1A(Homo sapiens (Human))
AchÉ

US Patent
LigandPNGBDBM463447(US10781182, Compound IA2-143 | US11091445, Compoun...)
Affinity DataKi:  2.10nMAssay Description:The binding assay was performed in melatonergic MT1 and MT2 receptors in order to check the receptor affinity for the ligand, i.e., the ability of th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelatonin receptor type 1A(Homo sapiens (Human))
AchÉ

US Patent
LigandPNGBDBM463447(US10781182, Compound IA2-143 | US11091445, Compoun...)
Affinity DataKi:  2.10nMAssay Description:The binding assay was performed in melatonergic MT1 and MT2 receptors in order to check the receptor affinity for the ligand, i.e., the ability of th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelatonin receptor type 1A(Homo sapiens (Human))
AchÉ

US Patent
LigandPNGBDBM463445(US10781182, Compound IA2-140 | US11091445, Compoun...)
Affinity DataKi:  2.20nMAssay Description:The binding assay was performed in melatonergic MT1 and MT2 receptors in order to check the receptor affinity for the ligand, i.e., the ability of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelatonin receptor type 1A(Homo sapiens (Human))
AchÉ

US Patent
LigandPNGBDBM463445(US10781182, Compound IA2-140 | US11091445, Compoun...)
Affinity DataKi:  2.20nMAssay Description:The binding assay was performed in melatonergic MT1 and MT2 receptors in order to check the receptor affinity for the ligand, i.e., the ability of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallothionein-2(Human)
AchÉ

US Patent
LigandPNGBDBM463443(US10781182, Compound IA2-120 | US11091445, Compoun...)
Affinity DataKi:  4.5nMAssay Description:The binding assay was performed in melatonergic MT1 and MT2 receptors in order to check the receptor affinity for the ligand, i.e., the ability of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelatonin receptor type 1B(Homo sapiens (Human))
AchÉ

US Patent
LigandPNGBDBM463443(US10781182, Compound IA2-120 | US11091445, Compoun...)
Affinity DataKi:  4.5nMAssay Description:The binding assay was performed in melatonergic MT1 and MT2 receptors in order to check the receptor affinity for the ligand, i.e., the ability of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50334369(3-(4-(Dimethylamino)phenyl)-1-(4-iodophenyl)-2-pro...)
Affinity DataKi:  6nMAssay Description:Displacement of [125I]DMIC from Amyloid beta (1 to 42) after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallothionein-2(Human)
AchÉ

US Patent
LigandPNGBDBM463445(US10781182, Compound IA2-140 | US11091445, Compoun...)
Affinity DataKi:  11nMAssay Description:The binding assay was performed in melatonergic MT1 and MT2 receptors in order to check the receptor affinity for the ligand, i.e., the ability of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelatonin receptor type 1B(Homo sapiens (Human))
AchÉ

US Patent
LigandPNGBDBM463445(US10781182, Compound IA2-140 | US11091445, Compoun...)
Affinity DataKi:  11nMAssay Description:The binding assay was performed in melatonergic MT1 and MT2 receptors in order to check the receptor affinity for the ligand, i.e., the ability of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelatonin receptor type 1A(Homo sapiens (Human))
AchÉ

US Patent
LigandPNGBDBM463446(US10781182, Compound IA2-142 | US11091445, Compoun...)
Affinity DataKi:  13nMAssay Description:The binding assay was performed in melatonergic MT1 and MT2 receptors in order to check the receptor affinity for the ligand, i.e., the ability of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelatonin receptor type 1A(Homo sapiens (Human))
AchÉ

US Patent
LigandPNGBDBM463446(US10781182, Compound IA2-142 | US11091445, Compoun...)
Affinity DataKi:  13nMAssay Description:The binding assay was performed in melatonergic MT1 and MT2 receptors in order to check the receptor affinity for the ligand, i.e., the ability of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50334371(3-(4-Methoxyphenyl)-1-(4-iodophenyl)-2-propyn-1-on...)
Affinity DataKi:  14nMAssay Description:Displacement of [125I]DMIC from Amyloid beta (1 to 42) after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50334370(3-(4-(Dimethylamino)phenyl)-1-(4-fruorophenyl)-2-p...)
Affinity DataKi:  20nMAssay Description:Displacement of [125I]DMIC from Amyloid beta (1 to 42) after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50122787(2-(4'-dimethylaminophenyl)-6-iodoimidazo[1,2-a]pyr...)
Affinity DataKi:  46nMAssay Description:Displacement of [125I]DMIC from Amyloid beta (1 to 42) after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50334372(3-(4-Hydroxyphenyl)-1-(4-iodophenyl)-2-propyn-1-on...)
Affinity DataKi:  326nMAssay Description:Displacement of [125I]DMIC from Amyloid beta (1 to 42) after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed