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Found 113 with Last Name = 'webb' and Initial = 'hk'
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50276625(1-Adamantan-1-yl-3-[3-(3-morpholin-4-yl-propoxy)-p...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of soluble epoxide hydrolase (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50276625(1-Adamantan-1-yl-3-[3-(3-morpholin-4-yl-propoxy)-p...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50296210(1-Adamantan-1-yl-3-[4-fluoro-3-(3-morpholin-4-yl-p...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50296214(1-(4-fluoro-3-(3-morpholinopropoxy)phenyl)-3-(4-(t...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50296223(1-(4-(3-morpholinopropoxy)phenyl)-3-(4-(trifluorom...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50296224(1-(4-(3-morpholinopropoxy)phenyl)-3-(4-(trifluorom...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM25743(1-cycloheptyl-3-(1-acetylpiperidin-4-yl)urea | US8...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50276673(1-(3-(3-morpholinopropoxy)phenyl)-3-(4-(trifluorom...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50276673(1-(3-(3-morpholinopropoxy)phenyl)-3-(4-(trifluorom...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of soluble epoxide hydrolase (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50223389(1-Adamantan-1-yl-3-[4-(3-morpholin-4-yl-propoxy)-p...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50296226(2-Adamantan-1-yl-N-[4-(3-morpholin-4-yl-propoxy)-p...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50296213(1-(4-fluoro-3-(3-morpholinopropoxy)phenyl)-3-(4-(t...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50296225(1-(4-chlorophenyl)-3-(4-(3-morpholinopropoxy)pheny...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335964(1-(1-nicotinoylpiperidin-4-yl)-3-(4-(trifluorometh...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335965(1-(1-(isopropylsulfonyl)piperidin-4-yl)-3-(4-(trif...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335966(1-Adamantan-1-yl-3-(1-methanesulfonyl-piperidin-4-...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50296197(1-(4-chlorophenyl)-3-(3-(3-morpholinopropoxy)pheny...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50296219(1-Adamantan-1-yl-3-[3-(3-morpholin-4-yl-propoxy)-c...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50276676(2-Adamantan-1-yl-N-[3-(3-morpholin-4-yl-propoxy)-p...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of soluble epoxide hydrolase (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50276676(2-Adamantan-1-yl-N-[3-(3-morpholin-4-yl-propoxy)-p...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335967(1-(1-(isopropylsulfonyl)piperidin-4-yl)-3-(4-(trif...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
Ar£Te Therapeutics

Curated by ChEMBL
LigandPNGBDBM50191854(CHEMBL436774 | N-(1-acetyl-piperidin-4-yl)-N'-(ada...)
Affinity DataIC50:  3nMAssay Description:Inhibition of mouse soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335968(1-(1-(methylsulfonyl)piperidin-4-yl)-3-(4-(trifluo...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335966(1-Adamantan-1-yl-3-(1-methanesulfonyl-piperidin-4-...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of soluble epoxide hydrolase in HUVEC assessed inhibition of as conversion of 14, 15-EET to 14, 15-DHETMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50276626(1-cyclohexyl-3-(3-(3-morpholinopropoxy)phenyl)urea...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50276626(1-cyclohexyl-3-(3-(3-morpholinopropoxy)phenyl)urea...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of soluble epoxide hydrolase (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50296215(1-(4-chlorophenyl)-3-(4-fluoro-3-(3-morpholinoprop...)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50296220(2-Adamantan-1-yl-N-[3-(3-morpholin-4-yl-propoxy)-c...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50296221(1-cyclohexyl-3-(4-(3-morpholinopropoxy)phenyl)urea...)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335969(1-(1-acetylpiperidin-4-yl)-3-(4,4-dimethylcyclohex...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335970(1-cyclohexyl-3-(1-picolinoylpiperidin-4-yl)urea | ...)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50296209(1-cyclohexyl-3-(4-fluoro-3-(3-morpholinopropoxy)ph...)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50296216(2-Adamantan-1-yl-N-[4-fluoro-3-(3-morpholin-4-yl-p...)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335964(1-(1-nicotinoylpiperidin-4-yl)-3-(4-(trifluorometh...)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of soluble epoxide hydrolase in HUVEC assessed inhibition of as conversion of 14, 15-EET to 14, 15-DHETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50191854(CHEMBL436774 | N-(1-acetyl-piperidin-4-yl)-N'-(ada...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50276674(1-(3-(3-morpholinopropoxy)phenyl)-3-(4-(trifluorom...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50276674(1-(3-(3-morpholinopropoxy)phenyl)-3-(4-(trifluorom...)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of soluble epoxide hydrolase (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335971(1-(1-acetylpiperidin-4-yl)-3-(3-(trifluoromethyl)p...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50296193(1-(3,4-difluorophenyl)-3-(3-(3-morpholinopropoxy)p...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335972(1-(1-acetylpiperidin-4-yl)-3-(4-(trifluoromethyl)p...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50276086(4-Adamantan-1-yl-N-[2-(4-benzyloxy-phenyl)-ethyl]-...)
Affinity DataIC50:  11nMAssay Description:Inhibition of soluble epoxide hydrolase (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM25744(3-(1-acetylpiperidin-4-yl)-1-[4-(trifluoromethoxy)...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335967(1-(1-(isopropylsulfonyl)piperidin-4-yl)-3-(4-(trif...)
Affinity DataIC50:  13nMAssay Description:Inhibition of soluble epoxide hydrolase in HUVEC assessed inhibition of as conversion of 14, 15-EET to 14, 15-DHETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335973(1-(1-acetylpiperidin-4-yl)-3-(4-tert-butylcyclohex...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50296196(1-(3-(3-morpholinopropoxy)phenyl)-3-(3-(trifluorom...)
Affinity DataIC50:  13.8nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335974(1-(1-Acetyl-piperidin-4-yl)-3-bicyclo[2.2.1]hept-7...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50296192(1-(4-fluorophenyl)-3-(3-(3-morpholinopropoxy)pheny...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50276225(1-(2-Adamantan-1-yl-ethyl)-3-[2-(4-benzyloxy-pheny...)
Affinity DataIC50:  15nMAssay Description:Inhibition of soluble epoxide hydrolase (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50276729(1-Adamantan-1-yl-3-[3-(3-morpholin-4-yl-propoxy)-p...)
Affinity DataIC50:  22nMAssay Description:Inhibition of soluble epoxide hydrolase (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
ArêTe Therapeutics

Curated by ChEMBL
LigandPNGBDBM50276801(3-Adamantan-1-yl-2-hydroxy-N-[3-(3-morpholin-4-yl-...)
Affinity DataIC50:  23nMAssay Description:Inhibition of soluble epoxide hydrolase (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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