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Found 24 with Last Name = 'weidley' and Initial = 'ef'
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226415(CHEMBL3142312)
Affinity DataKi:  0.880nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226412(CHEMBL3142332)
Affinity DataKi:  1.70nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226410(CHEMBL3142318)
Affinity DataKi:  1.70nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226411(CHEMBL3142329)
Affinity DataKi:  1.90nMAssay Description:Binding affinity against sigma receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226417(CHEMBL3142331)
Affinity DataKi:  2.5nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226413(CHEMBL2369777)
Affinity DataKi:  2.60nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226416(CHEMBL2369525)
Affinity DataKi:  3.90nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226414(CHEMBL2369778)
Affinity DataKi:  4.20nMAssay Description:Binding affinity against sigma receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226418(CHEMBL3142313)
Affinity DataKi:  7.80nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50282363(4-[2-Butyl-5-((E)-2-carboxy-3-thiophen-2-yl-propen...)
Affinity DataIC50:  0.160nMAssay Description:Tested for inhibition of [125I]- AII specific binding to rat mesenteric arteries, expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50011977((E)-2-butyl-1-(p-carboxybenzyl)-alpha-2-thenylimid...)
Affinity DataIC50:  1nMAssay Description:Tested for inhibition of [125I]- AII specific binding to rat mesenteric arteries, expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50048078(4-[2-Butyl-5-((E)-2-carboxy-3-thiophen-2-yl-propen...)
Affinity DataIC50:  1nMAssay Description:Tested for inhibition of [125I]- AII specific binding to rat mesenteric arteries, expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282362(4-[2-Butyl-5-((E)-2-carboxy-3-thiophen-2-yl-propen...)
Affinity DataIC50:  1.20nMAssay Description:Tested for Angiotensin II receptor, type 1 affinity in the absence of BSAMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50011975(4-[2-Butyl-5-((E)-2-carboxy-3-thiophen-2-yl-propen...)
Affinity DataIC50:  1.5nMAssay Description:Tested for inhibition of [125I]- AII specific binding to rat mesenteric arteries, expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50011977((E)-2-butyl-1-(p-carboxybenzyl)-alpha-2-thenylimid...)
Affinity DataIC50:  2nMAssay Description:Tested for Angiotensin II receptor, type 1 affinity in the absence of bovine serum albumin (BSA)More data for this Ligand-Target Pair
In DepthDetails ArticleDrugBank

TargetType-1 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284297(4-(2-Butyl-5-{[(R)-1-carboxy-2-(1H-indol-3-yl)-eth...)
Affinity DataIC50:  2.90nMAssay Description:Tested for inhibition of Angiotensin II specific binding to Angiotensin II receptor, type 1 in the recombinant human AT-1 receptor expressed in LhAT-...More data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50011977((E)-2-butyl-1-(p-carboxybenzyl)-alpha-2-thenylimid...)
Affinity DataIC50:  7.30nMAssay Description:Tested for Angiotensin II receptor, type 1 affinity in the presence of 0.25% bovine serum albumin (BSA)More data for this Ligand-Target Pair
In DepthDetails ArticleDrugBank

LigandPNGBDBM50282362(4-[2-Butyl-5-((E)-2-carboxy-3-thiophen-2-yl-propen...)
Affinity DataIC50:  12nMAssay Description:Tested for inhibition of [125I]- AII specific binding to rat mesenteric arteries, expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282362(4-[2-Butyl-5-((E)-2-carboxy-3-thiophen-2-yl-propen...)
Affinity DataIC50:  31nMAssay Description:Tested for Angiotensin II receptor, type 1 affinity in the presence of 0.25% BSAMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50048076(4-[2-Butyl-5-((E)-2-carboxy-3-thiophen-2-yl-propen...)
Affinity DataIC50:  35nMAssay Description:Tested for inhibition of [125I]- AII specific binding to rat mesenteric arteries, expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284298(4-(2-Butyl-5-{[(S)-1-carboxy-2-(1H-indol-3-yl)-eth...)
Affinity DataIC50:  48.3nMAssay Description:Tested for inhibition of Angiotensin II specific binding to Angiotensin II receptor, type 1 in the recombinant human AT-1 receptor expressed in LhAT-...More data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284295(4-{2-Butyl-5-[(carboxymethyl-amino)-methyl]-imidaz...)
Affinity DataIC50:  298nMAssay Description:Tested for inhibition of Angiotensin II specific binding to Angiotensin II receptor, type 1 in the recombinant human AT-1 receptor expressed in LhAT-...More data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50048069((E)-3-(3-Benzyl-2-butyl-3H-imidazol-4-yl)-2-thioph...)
Affinity DataIC50:  440nMAssay Description:Tested for binding affinity to Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50003266((E)-3-[2-Butyl-3-(2-chloro-benzyl)-3H-imidazol-4-y...)
Affinity DataIC50:  4.53E+3nMAssay Description:Tested for binding affinity to Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In DepthDetails Article