Affinity DataKi: 0.0120nMAssay Description:Displacement of [125I]Iodocyanopindolol from human adrenergic beta2 receptor expressed in insect sf9 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.0230nMAssay Description:Displacement of [125I]Iodocyanopindolol from human adrenergic beta1 receptor expressed in insect sf9 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Binding affinity to VDR ligand binding domain by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Binding affinity to VDR ligand binding domain by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Binding affinity to VDR ligand binding domain by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15.5nMAssay Description:Displacement of tetra-acetylated H4 peptide from human Brd4 bromodomain BD12 after 1 hr by FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 28.4nMAssay Description:Displacement of tetra-acetylated H4 peptide from human Brd3 bromodomain BD12 after 1 hr by FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Binding affinity to VDR ligand binding domain by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 29.9nMAssay Description:Displacement of tetra-acetylated H4 peptide from human Brd2 bromodomain BD12 after 1 hr by FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 32.5nMAssay Description:Displacement of tetra-acetylated H4 peptide from human Brd2 bromodomain BD12 after 1 hr by FRET analysisMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
The Royal Institution For The Advancement of Learning/Mcgill University
US Patent
The Royal Institution For The Advancement of Learning/Mcgill University
US Patent
Affinity DataIC50: 33.8nMpH: 8.1 T: 2°CAssay Description:Boc-Lys(Ac)-7-amino-4-methylcoumarin (Boc-Lys(Ac)-AMC) was used as substrate for the HDAC assays. Substrate solution was prepared as follow: Boc(Lys-...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Binding affinity to VDR ligand binding domain by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 36.1nMAssay Description:Displacement of tetra-acetylated H4 peptide from human Brd4 bromodomain BD12 after 1 hr by FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 42.4nMAssay Description:Displacement of tetra-acetylated H4 peptide from human Brd3 bromodomain BD12 after 1 hr by FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 87nMAssay Description:Binding affinity to VDR ligand binding domain by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 107nMAssay Description:Binding affinity to VDR-LBD by fluorescence polarization competition assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
The Royal Institution For The Advancement of Learning/Mcgill University
US Patent
The Royal Institution For The Advancement of Learning/Mcgill University
US Patent
Affinity DataIC50: 150nMAssay Description:Inhibition of HDAC3 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 185nMAssay Description:Binding affinity to VDR ligand binding domain by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 196nMAssay Description:Binding affinity to VDR ligand binding domain by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of HDAC2 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 213nMAssay Description:Binding affinity to VDR ligand binding domain by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 248nMAssay Description:Binding affinity to VDR ligand binding domain by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 248nMAssay Description:Binding affinity to VDR-LBD by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Binding affinity to VDR ligand binding domain by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 321nMAssay Description:Binding affinity to VDR ligand binding domain by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of HDAC6 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 524nMAssay Description:Binding affinity to VDR ligand binding domain by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 557nMpH: 8.1 T: 2°CAssay Description:Boc-Lys(Ac)-7-amino-4-methylcoumarin (Boc-Lys(Ac)-AMC) was used as substrate for the HDAC assays. Substrate solution was prepared as follow: Boc(Lys-...More data for this Ligand-Target Pair
Affinity DataIC50: 580nMAssay Description:Inhibition of HDAC6 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 580nMpH: 8.1 T: 2°CAssay Description:Boc-Lys(Ac)-7-amino-4-methylcoumarin (Boc-Lys(Ac)-AMC) was used as substrate for the HDAC assays. Substrate solution was prepared as follow: Boc(Lys-...More data for this Ligand-Target Pair
Affinity DataIC50: 1.08E+3nMpH: 8.1 T: 2°CAssay Description:Boc-Lys(Ac)-7-amino-4-methylcoumarin (Boc-Lys(Ac)-AMC) was used as substrate for the HDAC assays. Substrate solution was prepared as follow: Boc(Lys-...More data for this Ligand-Target Pair
Affinity DataIC50: 1.57E+3nMpH: 8.1 T: 2°CAssay Description:Boc-Lys(Ac)-7-amino-4-methylcoumarin (Boc-Lys(Ac)-AMC) was used as substrate for the HDAC assays. Substrate solution was prepared as follow: Boc(Lys-...More data for this Ligand-Target Pair
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of HDAC6 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.97E+3nMpH: 8.1 T: 2°CAssay Description:Boc-Lys(Ac)-7-amino-4-methylcoumarin (Boc-Lys(Ac)-AMC) was used as substrate for the HDAC assays. Substrate solution was prepared as follow: Boc(Lys-...More data for this Ligand-Target Pair
Affinity DataIC50: 2.65E+3nMpH: 8.1 T: 2°CAssay Description:Boc-Lys(Ac)-7-amino-4-methylcoumarin (Boc-Lys(Ac)-AMC) was used as substrate for the HDAC assays. Substrate solution was prepared as follow: Boc(Lys-...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HDAC6 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.13E+3nMpH: 8.1 T: 2°CAssay Description:Boc-Lys(Ac)-7-amino-4-methylcoumarin (Boc-Lys(Ac)-AMC) was used as substrate for the HDAC assays. Substrate solution was prepared as follow: Boc(Lys-...More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
The Royal Institution For The Advancement of Learning/Mcgill University
US Patent
The Royal Institution For The Advancement of Learning/Mcgill University
US Patent
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of HDAC3 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+3nMpH: 8.1 T: 2°CAssay Description:Boc-Lys(Ac)-7-amino-4-methylcoumarin (Boc-Lys(Ac)-AMC) was used as substrate for the HDAC assays. Substrate solution was prepared as follow: Boc(Lys-...More data for this Ligand-Target Pair
Affinity DataIC50: 3.94E+3nMpH: 8.1 T: 2°CAssay Description:Boc-Lys(Ac)-7-amino-4-methylcoumarin (Boc-Lys(Ac)-AMC) was used as substrate for the HDAC assays. Substrate solution was prepared as follow: Boc(Lys-...More data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+3nMpH: 8.1 T: 2°CAssay Description:Boc-Lys(Ac)-7-amino-4-methylcoumarin (Boc-Lys(Ac)-AMC) was used as substrate for the HDAC assays. Substrate solution was prepared as follow: Boc(Lys-...More data for this Ligand-Target Pair
Affinity DataIC50: 5.03E+3nMpH: 8.1 T: 2°CAssay Description:Boc-Lys(Ac)-7-amino-4-methylcoumarin (Boc-Lys(Ac)-AMC) was used as substrate for the HDAC assays. Substrate solution was prepared as follow: Boc(Lys-...More data for this Ligand-Target Pair
Affinity DataIC50: 7.40E+3nMpH: 8.1 T: 2°CAssay Description:Boc-Lys(Ac)-7-amino-4-methylcoumarin (Boc-Lys(Ac)-AMC) was used as substrate for the HDAC assays. Substrate solution was prepared as follow: Boc(Lys-...More data for this Ligand-Target Pair
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of HDAC6 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
The Royal Institution For The Advancement of Learning/Mcgill University
US Patent
The Royal Institution For The Advancement of Learning/Mcgill University
US Patent
Affinity DataIC50: 9.83E+3nMpH: 8.1 T: 2°CAssay Description:Boc-Lys(Ac)-7-amino-4-methylcoumarin (Boc-Lys(Ac)-AMC) was used as substrate for the HDAC assays. Substrate solution was prepared as follow: Boc(Lys-...More data for this Ligand-Target Pair
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of HDAC2 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
The Royal Institution For The Advancement of Learning/Mcgill University
US Patent
The Royal Institution For The Advancement of Learning/Mcgill University
US Patent
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of HDAC3 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
The Royal Institution For The Advancement of Learning/Mcgill University
US Patent
The Royal Institution For The Advancement of Learning/Mcgill University
US Patent
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of HDAC3 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of HDAC2 after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
The Royal Institution For The Advancement of Learning/Mcgill University
US Patent
The Royal Institution For The Advancement of Learning/Mcgill University
US Patent
Affinity DataIC50: 1.70E+4nMpH: 8.1 T: 2°CAssay Description:Boc-Lys(Ac)-7-amino-4-methylcoumarin (Boc-Lys(Ac)-AMC) was used as substrate for the HDAC assays. Substrate solution was prepared as follow: Boc(Lys-...More data for this Ligand-Target Pair