Affinity DataKi: 0.0910nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Antagonist activity at muscarinic M2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Antagonist activity at muscarinic M1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.276nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.290nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.305nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.340nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.350nMAssay Description:Antagonist activity at muscarinic M4 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.397nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.634nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.730nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.765nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.990nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Antagonist activity at muscarinic M5 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:In vitro Binding affinity towards alpha-3 (PC12) nAChR was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:In vitro Binding affinity towards alpha-7 nAChR was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
Affinity DataKi: 4.70nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.10nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.40nMAssay Description:In vitro Binding affinity towards alpha-7 nAChR was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 6.90nMAssay Description:In vitro Binding affinity towards alpha-7 nAChR was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 7.70nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
Affinity DataKi: 8.80nMAssay Description:In vitro Binding affinity towards alpha-7 nAChR was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataKi: 220nMAssay Description:In vitro Binding affinity towards alpha-3 (PC12) nAChR was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 480nMAssay Description:In vitro Binding affinity towards alpha-7 nAChR was determinedMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataKi: 2.30E+3nMAssay Description:In vitro Binding affinity towards alpha-3 (PC12) nAChR was determinedMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataKi: 2.60E+3nMAssay Description:In vitro Binding affinity towards alpha-1-beta-1-gamma-delta nAChR was determinedMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+3nMAssay Description:In vitro Binding affinity towards alpha-7 nAChR was determinedMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataKi: 3.00E+3nMAssay Description:In vitro Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 was determinedMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataKi: 5.50E+3nMAssay Description:In vitro Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 was determinedMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataKi: 7.80E+3nMAssay Description:In vitro Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 was determinedMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:In vitro Binding affinity towards alpha-7 nAChR was determinedMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataKi: 1.40E+4nMAssay Description:In vitro Binding affinity towards alpha-1-beta-1-gamma-delta nAChR was determinedMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataKi: 1.60E+4nMAssay Description:In vitro Binding affinity towards alpha-3 (PC12) nAChR was determinedMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataKi: 2.70E+4nMAssay Description:In vitro Binding affinity towards alpha-1-beta-1-gamma delta nAChR was determinedMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataKi: 3.80E+4nMAssay Description:In vitro Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 was determinedMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataKi: 4.60E+4nMAssay Description:In vitro Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 was determinedMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataKi: 5.50E+4nMAssay Description:In vitro Binding affinity towards 5-hydroxytryptamine 3 receptor was determinedMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataKi: 6.70E+4nMAssay Description:In vitro Binding affinity towards 5-hydroxytryptamine 3 receptor was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
Affinity DataIC50: 0.639nMAssay Description:The enzyme and peptide solution were incubated with compound for 15 minutes at room temp before the reaction was initiated by the addition of ATP. Th...More data for this Ligand-Target Pair
Affinity DataIC50: 0.650nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat. no. 784900) using an Echo 555 acoustic dispenser, and dimethyl sulfoxide ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.822nMAssay Description:The enzyme and peptide solution were incubated with compound for 15 minutes at room temp before the reaction was initiated by the addition of ATP. Th...More data for this Ligand-Target Pair