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Found 28 with Last Name = 'wright' and Initial = 'pa'
TargetNeutrophil elastase(Homo sapiens (Human))
The Oxford Centre For Molecular Sciences

Curated by ChEMBL
LigandPNGBDBM50089098(CHEMBL266704 | Cys-Phe-Leu-Glu-Ala-Ile-Pro-Met-Asp...)
Affinity DataKi:  1.90E+4nMAssay Description:Competitive inhibition constant of the compound was tested against Human neutrophil elastase using the reporter substrate MeO-AAPV-pNaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
The Oxford Centre For Molecular Sciences

Curated by ChEMBL
LigandPNGBDBM50089095(CHEMBL216418 | Met-Phe-Leu-Glu-Ala-Ile-Pro-Met-Ser...)
Affinity DataKi:  2.70E+4nMAssay Description:Competitive inhibition constant of the compound was tested against Human neutrophil elastase using the reporter substrate MeO-AAPV-pNaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-like elastase family member 2A(Sus scrofa)
The Oxford Centre For Molecular Sciences

Curated by ChEMBL
LigandPNGBDBM50089095(CHEMBL216418 | Met-Phe-Leu-Glu-Ala-Ile-Pro-Met-Ser...)
Affinity DataKi:  1.00E+5nMAssay Description:Peptide was tested for inhibition constant for competitive inhibition using Suc-AAPA-pNa and Pancreatic elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
The Oxford Centre For Molecular Sciences

Curated by ChEMBL
LigandPNGBDBM50089095(CHEMBL216418 | Met-Phe-Leu-Glu-Ala-Ile-Pro-Met-Ser...)
Affinity DataKi:  1.60E+5nMAssay Description:Competitive inhibition constant of the compound was tested against Chymotrypsinogen using the reporter substrate Suc-AAPA-pNaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-like elastase family member 2A(Sus scrofa)
The Oxford Centre For Molecular Sciences

Curated by ChEMBL
LigandPNGBDBM50089098(CHEMBL266704 | Cys-Phe-Leu-Glu-Ala-Ile-Pro-Met-Asp...)
Affinity DataKi:  1.90E+5nMAssay Description:Peptide was tested for inhibition constant for competitive inhibition using Suc-AAPA-pNa and Pancreatic elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
The Oxford Centre For Molecular Sciences

Curated by ChEMBL
LigandPNGBDBM50089094(CHEMBL414810 | Met-Phe-Leu-Glu-Ala-Ile-Pro-Met-Ser)
Affinity DataKi:  1.90E+5nMAssay Description:Competitive inhibition constant of the compound was tested against Human neutrophil elastase using the reporter substrate MeO-AAPV-pNaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
The Oxford Centre For Molecular Sciences

Curated by ChEMBL
LigandPNGBDBM50089098(CHEMBL266704 | Cys-Phe-Leu-Glu-Ala-Ile-Pro-Met-Asp...)
Affinity DataKi:  2.40E+5nMAssay Description:Competitive inhibition constant of the compound was tested against Chymotrypsinogen using the reporter substrate Suc-AAPA-pNaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
The Oxford Centre For Molecular Sciences

Curated by ChEMBL
LigandPNGBDBM50089096(CHEMBL278549 | Met-Phe-Leu-Glu-Ala-Ile-Pro-Met | e...)
Affinity DataKi:  2.70E+5nMAssay Description:Competitive inhibition constant of the compound was tested against Human neutrophil elastase using the reporter substrate MeO-AAPV-pNaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
The Oxford Centre For Molecular Sciences

Curated by ChEMBL
LigandPNGBDBM50089097(CHEMBL21028 | Met-Phe-Leu-Glu-Ala-Ile-Pro-Lys)
Affinity DataKi:  5.40E+5nMAssay Description:Competitive inhibition constant of the compound was tested against trypsin using the reporter substrate Ac-R-pNaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-like elastase family member 2A(Sus scrofa)
The Oxford Centre For Molecular Sciences

Curated by ChEMBL
LigandPNGBDBM50089099((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-4-methylsulfanyl-...)
Affinity DataKi:  1.10E+6nMAssay Description:Peptide was tested for inhibition constant for competitive inhibition using Suc-AAPA-pNa and Pancreatic elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
The Oxford Centre For Molecular Sciences

Curated by ChEMBL
LigandPNGBDBM50089096(CHEMBL278549 | Met-Phe-Leu-Glu-Ala-Ile-Pro-Met | e...)
Affinity DataKi:  2.30E+6nMAssay Description:Competitive inhibition constant of the compound was tested against Chymotrypsinogen using the reporter substrate Suc-AAPA-pNaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
The Oxford Centre For Molecular Sciences

Curated by ChEMBL
LigandPNGBDBM50089094(CHEMBL414810 | Met-Phe-Leu-Glu-Ala-Ile-Pro-Met-Ser)
Affinity DataKi:  3.10E+6nMAssay Description:Competitive inhibition constant of the compound was tested against Chymotrypsinogen using the reporter substrate Suc-AAPA-pNaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-like elastase family member 2A(Sus scrofa)
The Oxford Centre For Molecular Sciences

Curated by ChEMBL
LigandPNGBDBM50089094(CHEMBL414810 | Met-Phe-Leu-Glu-Ala-Ile-Pro-Met-Ser)
Affinity DataKi:  5.80E+6nMAssay Description:Peptide was tested for inhibition constant for competitive inhibition using Suc-AAPA-pNa and Pancreatic elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316213(4-((3-(2-(6-(2,2-diphenylethylamino)-9-((2R,3R,4S,...)
Affinity DataIC50:  0.400nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316212(6-(2,2-diphenylethylamino)-9-((2R,3R,4S,5S)-5-(eth...)
Affinity DataIC50:  4nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316210(6-(2,2-diphenylethylamino)-9-((2R,3R,4S,5S)-5-(eth...)
Affinity DataIC50:  4nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316202(6-(2,2-diphenylethylamino)-9-((2R,3R,4S,5S)-5-(eth...)
Affinity DataIC50:  5nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316205(CHEMBL1096889 | N-(2-(3-(2-(diisopropylamino)ethyl...)
Affinity DataIC50:  5nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316211(CHEMBL1096895 | N-(2-(3-(4-((diethylamino)methyl)b...)
Affinity DataIC50:  5nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50233816((2S,3S,4R,5R)-5-(2-((3-(2-(cyclopentyl(isopropyl)a...)
Affinity DataIC50:  6nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316209(CHEMBL1096893 | N-(2-(3-benzylureido)ethyl)-6-(2,2...)
Affinity DataIC50:  6nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316204(CHEMBL1096888 | N-(2-(3-(2-(cyclopentyl(isopropyl)...)
Affinity DataIC50:  7nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316208(6-(2,2-diphenylethylamino)-9-((2R,3R,4S,5S)-5-(eth...)
Affinity DataIC50:  10nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316206(CHEMBL1096890 | N-(2-(3-(2-(3,4-dihydroisoquinolin...)
Affinity DataIC50:  10nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50233809((2S,3S,4R,5R)-5-(6-(2,2-diphenylethylamino)-2-((3-...)
Affinity DataIC50:  17nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316203(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)te...)
Affinity DataIC50:  45nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50233810(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-t...)
Affinity DataIC50:  65nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50316207(6-(2,2-diphenylethylamino)-9-((2R,3R,4S,5S)-5-(eth...)
Affinity DataIC50:  305nMAssay Description:Agonist activity at adenosine A2A receptor in fMLP-stimulated human neutrophils assessed as inhibition of superoxide production by colorimetric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed