Affinity DataKi: 0.100nM ΔG°: -57.5kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Binding affinity towards vitronectin receptor (AlphaV-beta3 integrin).More data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by PDSP Ki Database
Smithkline Beecham Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 0.300nM ΔG°: -54.7kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by PDSP Ki Database
Smithkline Beecham Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 0.5nMAssay Description:Binding affinity towards vitronectin receptor (AlphaV-beta3 integrin).More data for this Ligand-Target Pair
Affinity DataKi: 0.5nM ΔG°: -52.6kJ/molepH: 7.4 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nM ΔG°: -52.6kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Affinity for alphaIIb-beta3 integrinMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nM ΔG°: -52.0kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of RON by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of recombinant c-met-mediated gastrin phosphorylation by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of RON by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataKi: <1nMAssay Description:Inhibition of human PI3Kalpha expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataKi: <1nMAssay Description:Inhibition of human PI3Kalpha expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataKi: <1nMAssay Description:Inhibition of human PI3Kalpha expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataKi: <1nMAssay Description:Inhibition of human PI3Kalpha expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataKi: <1nMAssay Description:Inhibition of human PI3Kalpha expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataKi: <1nMAssay Description:Inhibition of human PI3Kalpha expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataKi: <1nMAssay Description:Inhibition of human PI3Kalpha expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataKi: <1nMAssay Description:Inhibition of human PI3Kalpha expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataKi: <1nMAssay Description:Inhibition of human PI3Kalpha expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataKi: <1nMAssay Description:Inhibition of human PI3Kalpha expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -50.9kJ/molepH: 7.4 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -50.9kJ/molepH: 7.4 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
Affinity DataKi: 1.02nM ΔG°: -50.8kJ/molepH: 7.4 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nM ΔG°: -50.6kJ/molepH: 7.4 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nM ΔG°: -50.6kJ/molepH: 7.4 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Inhibition of human PI3Kalpha expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Inhibition of human PI3Kdelta expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nM ΔG°: -50.4kJ/molepH: 7.4 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair