Found 397 with Last Name = 'yang' and Initial = 'i' 
Affinity DataKi: 27nMAssay Description:Inhibition of human thymidylate synthase at 600 uM concentration of 5,10-CH2-H4PteGluMore data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Inhibition of human thymidylate synthase at 600 uM concentration of 5,10-CH2-H4PteGluMore data for this Ligand-Target Pair
Affinity DataKi: 85nMAssay Description:Competitive inhibition of the human thymidylate synthase at 600 uM of [dUMP]More data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:Competitive inhibition of the human thymidylate synthase at 28 uM as Ki(slope) of 5,10-CH2-H4PteGluMore data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Inhibition of Staphylococcus aureus His6-tagged CrtM expressed in Escherichia coli BL21(DE3) using Farnesyl pyrophosphate as substrate incubated for ...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 450nMAssay Description:Inhibition of Staphylococcus aureus His6-tagged CrtM expressed in Escherichia coli BL21(DE3) using Farnesyl pyrophosphate as substrate incubated for ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:c-Abl kinase activity was measured by Promega’s ADP-Glo ® Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/µl) is incubated with 5 µL...More data for this Ligand-Target Pair
Affinity DataIC50: 0.710nMAssay Description:c-Abl kinase activity was measured by Promega’s ADP-Glo ® Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/µl) is incubated with 5 µL...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:c-Abl kinase activity was measured by Promega’s ADP-Glo ® Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/µl) is incubated with 5 µL...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:c-Abl kinase activity was measured by Promega’s ADP-Glo ® Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/µl) is incubated with 5 µL...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:c-Abl kinase activity was measured by Promega’s ADP-Glo ® Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/µl) is incubated with 5 µL...More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:c-Abl kinase activity was measured by Promega’s ADP-Glo ® Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/µl) is incubated with 5 µL...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:c-Abl kinase activity was measured by Promega’s ADP-Glo ® Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/µl) is incubated with 5 µL...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:c-Abl kinase activity was measured by Promega’s ADP-Glo ® Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/µl) is incubated with 5 µL...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:c-Abl kinase activity was measured by Promega’s ADP-Glo ® Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/µl) is incubated with 5 µL...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:c-Abl kinase activity was measured by Promega’s ADP-Glo ® Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/µl) is incubated with 5 µL...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:c-Abl kinase activity was measured by Promega’s ADP-Glo ® Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/µl) is incubated with 5 µL...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:c-Abl kinase activity was measured by Promega’s ADP-Glo ® Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/µl) is incubated with 5 µL...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:c-Abl kinase activity was measured by Promega’s ADP-Glo ® Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/µl) is incubated with 5 µL...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:c-Abl kinase activity was measured by Promega’s ADP-Glo ® Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/µl) is incubated with 5 µL...More data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:c-Abl kinase activity was measured by Promega’s ADP-Glo ® Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/µl) is incubated with 5 µL...More data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:c-Abl kinase activity was measured by Promega’s ADP-Glo ® Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/µl) is incubated with 5 µL...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
1St Biotherapeutics
US Patent
1St Biotherapeutics
US Patent
Affinity DataIC50: 6.67nMAssay Description:GST-tagged recombinant human RIPK2(25 ng) is incubated with 5 µL of compounds (0.5% DMSO), 5 µL of MBP (0.5 µg/µl) and 5 µL of ATP (25 µM) in buffer ...More data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:c-Abl kinase activity was measured by Promega’s ADP-Glo ® Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/µl) is incubated with 5 µL...More data for this Ligand-Target Pair
Affinity DataIC50: 7.60nMAssay Description:c-Abl kinase activity was measured by Promega’s ADP-Glo ® Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/µl) is incubated with 5 µL...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
1St Biotherapeutics
US Patent
1St Biotherapeutics
US Patent
Affinity DataIC50: 8.25nMAssay Description:GST-tagged recombinant human RIPK2(25 ng) is incubated with 5 µL of compounds (0.5% DMSO), 5 µL of MBP (0.5 µg/µl) and 5 µL of ATP (25 µM) in buffer ...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
1St Biotherapeutics
US Patent
1St Biotherapeutics
US Patent
Affinity DataIC50: 8.37nMAssay Description:GST-tagged recombinant human RIPK2(25 ng) is incubated with 5 µL of compounds (0.5% DMSO), 5 µL of MBP (0.5 µg/µl) and 5 µL of ATP (25 µM) in buffer ...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
1St Biotherapeutics
US Patent
1St Biotherapeutics
US Patent
Affinity DataIC50: 8.77nMAssay Description:GST-tagged recombinant human RIPK2(25 ng) is incubated with 5 µL of compounds (0.5% DMSO), 5 µL of MBP (0.5 µg/µl) and 5 µL of ATP (25 µM) in buffer ...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:c-Abl kinase activity was measured by Promega’s ADP-Glo ® Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/µl) is incubated with 5 µL...More data for this Ligand-Target Pair
Affinity DataIC50: 9.20nMAssay Description:c-Abl kinase activity was measured by Promega’s ADP-Glo ® Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/µl) is incubated with 5 µL...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
1St Biotherapeutics
US Patent
1St Biotherapeutics
US Patent
Affinity DataIC50: 10.2nMAssay Description:GST-tagged recombinant human RIPK2(25 ng) is incubated with 5 µL of compounds (0.5% DMSO), 5 µL of MBP (0.5 µg/µl) and 5 µL of ATP (25 µM) in buffer ...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
1St Biotherapeutics
US Patent
1St Biotherapeutics
US Patent
Affinity DataIC50: 11nMAssay Description:GST-tagged recombinant human RIPK2(25 ng) is incubated with 5 µL of compounds (0.5% DMSO), 5 µL of MBP (0.5 µg/µl) and 5 µL of ATP (25 µM) in buffer ...More data for this Ligand-Target Pair
Affinity DataIC50: 11.2nMAssay Description:c-Abl kinase activity was measured by Promega’s ADP-Glo ® Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/µl) is incubated with 5 µL...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
1St Biotherapeutics
US Patent
1St Biotherapeutics
US Patent
Affinity DataIC50: 11.4nMAssay Description:GST-tagged recombinant human RIPK2(25 ng) is incubated with 5 µL of compounds (0.5% DMSO), 5 µL of MBP (0.5 µg/µl) and 5 µL of ATP (25 µM) in buffer ...More data for this Ligand-Target Pair
Affinity DataIC50: 12.2nMAssay Description:c-Abl kinase activity was measured by Promega’s ADP-Glo ® Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/µl) is incubated with 5 µL...More data for this Ligand-Target Pair
Affinity DataIC50: 12.3nMAssay Description:c-Abl kinase activity was measured by Promega’s ADP-Glo ® Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/µl) is incubated with 5 µL...More data for this Ligand-Target Pair
Affinity DataIC50: 12.4nMAssay Description:c-Abl kinase activity was measured by Promega’s ADP-Glo ® Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/µl) is incubated with 5 µL...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:c-Abl kinase activity was measured by Promega’s ADP-Glo ® Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/µl) is incubated with 5 µL...More data for this Ligand-Target Pair
Affinity DataIC50: 13.9nMAssay Description:c-Abl kinase activity was measured by Promega’s ADP-Glo ® Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/µl) is incubated with 5 µL...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
1St Biotherapeutics
US Patent
1St Biotherapeutics
US Patent
Affinity DataIC50: 13.9nMAssay Description:GST-tagged recombinant human RIPK2(25 ng) is incubated with 5 µL of compounds (0.5% DMSO), 5 µL of MBP (0.5 µg/µl) and 5 µL of ATP (25 µM) in buffer ...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
1St Biotherapeutics
US Patent
1St Biotherapeutics
US Patent
Affinity DataIC50: 14.9nMAssay Description:GST-tagged recombinant human RIPK2(25 ng) is incubated with 5 µL of compounds (0.5% DMSO), 5 µL of MBP (0.5 µg/µl) and 5 µL of ATP (25 µM) in buffer ...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Homo sapiens (Human))
1St Biotherapeutics
US Patent
1St Biotherapeutics
US Patent
Affinity DataIC50: 15nMAssay Description:The LRRK2 and LRRK2 G2019S kinase assays were performed using the AdaptaTM technology in ThermoFisher Scientific. This experiment was carried out acc...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
1St Biotherapeutics
US Patent
1St Biotherapeutics
US Patent
Affinity DataIC50: 15.1nMAssay Description:GST-tagged recombinant human RIPK2(25 ng) is incubated with 5 µL of compounds (0.5% DMSO), 5 µL of MBP (0.5 µg/µl) and 5 µL of ATP (25 µM) in buffer ...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
1St Biotherapeutics
US Patent
1St Biotherapeutics
US Patent
Affinity DataIC50: 15.4nMAssay Description:GST-tagged recombinant human RIPK2(25 ng) is incubated with 5 µL of compounds (0.5% DMSO), 5 µL of MBP (0.5 µg/µl) and 5 µL of ATP (25 µM) in buffer ...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
1St Biotherapeutics
US Patent
1St Biotherapeutics
US Patent
Affinity DataIC50: 15.9nMAssay Description:GST-tagged recombinant human RIPK2(25 ng) is incubated with 5 µL of compounds (0.5% DMSO), 5 µL of MBP (0.5 µg/µl) and 5 µL of ATP (25 µM) in buffer ...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
1St Biotherapeutics
US Patent
1St Biotherapeutics
US Patent
Affinity DataIC50: 16.1nMAssay Description:GST-tagged recombinant human RIPK2(25 ng) is incubated with 5 µL of compounds (0.5% DMSO), 5 µL of MBP (0.5 µg/µl) and 5 µL of ATP (25 µM) in buffer ...More data for this Ligand-Target Pair
Affinity DataIC50: 19.4nMAssay Description:c-Abl kinase activity was measured by Promega’s ADP-Glo ® Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/µl) is incubated with 5 µL...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
1St Biotherapeutics
US Patent
1St Biotherapeutics
US Patent
Affinity DataIC50: 19.9nMAssay Description:GST-tagged recombinant human RIPK2(25 ng) is incubated with 5 µL of compounds (0.5% DMSO), 5 µL of MBP (0.5 µg/µl) and 5 µL of ATP (25 µM) in buffer ...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of AChE (unknown origin) assessed as inhibition of acetylcholine hydrolysis preincubated for 15 mins by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 20.2nMAssay Description:c-Abl kinase activity was measured by Promega’s ADP-Glo ® Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/µl) is incubated with 5 µL...More data for this Ligand-Target Pair
