Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant MAOB assessed as reduction in H2O2 production from p-tyramine incubated for 15 mins by Amplex red reagent based fluor...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 144nMAssay Description:Inhibition of human recombinant MAOB assessed as reduction in H2O2 production from p-tyramine incubated for 15 mins by Amplex red reagent based fluor...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 780nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataIC50: 840nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Yunnan Normal University
Curated by ChEMBL
Yunnan Normal University
Curated by ChEMBL
Affinity DataIC50: 960nMAssay Description:Inhibition of human quinone reductase 2 expressed in Escherichia coli BL21(DE3) assessed as N-methyldihydronicotinamide oxidation per mg of protein a...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human PMA-differentiated THP-1 cells assessed as reduction in nigericin-induced IL-1beta le...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataIC50: 2.41E+3nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataIC50: 3.39E+3nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.52E+3nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Yunnan Normal University
Curated by ChEMBL
Yunnan Normal University
Curated by ChEMBL
Affinity DataIC50: 3.84E+3nMAssay Description:Inhibition of human quinone reductase 2 expressed in Escherichia coli BL21(DE3) assessed as N-methyldihydronicotinamide oxidation per mg of protein a...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataIC50: 3.89E+3nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5.23E+3nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 6.56E+3nMAssay Description:Inhibition of human recombinant MAOA assessed as reduction in H2O2 production from p-tyramine incubated for 15 mins by Amplex red reagent based fluor...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataIC50: 7.25E+3nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7.54E+3nMAssay Description:Inhibition of human recombinant MAOB assessed as reduction in H2O2 production from p-tyramine incubated for 15 mins by Amplex red reagent based fluor...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataIC50: 7.72E+3nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Woosuk University
Curated by ChEMBL
Woosuk University
Curated by ChEMBL
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.52E+4nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.57E+4nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.22E+4nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.32E+4nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 2.42E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human PMA-differentiated THP-1 cells assessed as reduction in nigericin-induced IL-1beta le...More data for this Ligand-Target Pair
Affinity DataIC50: 2.68E+4nMAssay Description:Inhibition of aromatase preincubated with 2.6 mM NADP+ for 10 mins before substrate addition measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.68E+4nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.07E+4nMAssay Description:Inhibition of aromatase preincubated with 2.6 mM NADP+ for 10 mins before substrate addition measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.23E+4nMAssay Description:Inhibition of aromatase preincubated with 2.6 mM NADP+ for 10 mins before substrate addition measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.53E+4nMAssay Description:Inhibition of aromatase preincubated with 2.6 mM NADP+ for 10 mins before substrate addition measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.84E+4nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5.47E+4nMAssay Description:Inhibition of tyrosinase activity in alpha-MSH-stimulated mouse B16 cells using L-tyrosine as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 5.79E+4nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 6.64E+4nMAssay Description:Inhibition of tyrosinase activity in alpha-MSH-stimulated mouse B16 cells using L-tyrosine as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 6.73E+4nMAssay Description:Displacement of [3H]R-1881 from Androgen receptor of LNCaP cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.89E+4nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair