Compile Data Set for Download or QSAR
maximum 50k data
Found 214 with Last Name = 'yap' and Initial = 'k'
TargetCathepsin G(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520048(CHEMBL4450993)
Affinity DataKi: <0.100nMAssay Description:Inhibition of human cathepsin G using Suc-AAPF-MCA as substrate at pH 7.2 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520068(CHEMBL4447828)
Affinity DataKi: <0.100nMAssay Description:Inhibition of bovine beta-trypsin using L-BAPNA as substrate preincubated for 5 mins followed by substrate addition measured after 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520051(CHEMBL4592765)
Affinity DataKi:  0.220nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520051(CHEMBL4592765)
Affinity DataKi:  0.260nMAssay Description:Inhibition of human cathepsin G using Suc-AAPF-MCA as substrate at pH 7.2 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B2(Homo sapiens)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520048(CHEMBL4450993)
Affinity DataKi:  0.420nMAssay Description:Inhibition of human chymotrypsin using Suc-AAPF-MCA as substrate at pH 8 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B2(Homo sapiens)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520063(CHEMBL4586444)
Affinity DataKi:  0.880nMAssay Description:Inhibition of human chymotrypsin using Suc-AAPF-MCA as substrate at pH 8 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B2(Homo sapiens)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520058(CHEMBL4469390)
Affinity DataKi:  1.5nMAssay Description:Inhibition of human chymotrypsin using Suc-AAPF-MCA as substrate at pH 8 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520048(CHEMBL4450993)
Affinity DataKi:  1.70nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520049(CHEMBL4560112)
Affinity DataKi:  1.80nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520060(CHEMBL4465306)
Affinity DataKi:  2.20nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520063(CHEMBL4586444)
Affinity DataKi:  5.70nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520050(CHEMBL4457132)
Affinity DataKi:  6.60nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520058(CHEMBL4469390)
Affinity DataKi:  7.40nMAssay Description:Inhibition of human cathepsin G using Suc-AAPF-MCA as substrate at pH 7.2 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520064(CHEMBL4590739)
Affinity DataKi:  7.5nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520063(CHEMBL4586444)
Affinity DataKi:  8.20nMAssay Description:Inhibition of human cathepsin G using Suc-AAPF-MCA as substrate at pH 7.2 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520066(CHEMBL4442550)
Affinity DataKi:  10nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B2(Homo sapiens)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520064(CHEMBL4590739)
Affinity DataKi:  11nMAssay Description:Inhibition of human chymotrypsin using Suc-AAPF-MCA as substrate at pH 8 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520059(CHEMBL4561218)
Affinity DataKi:  11nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520064(CHEMBL4590739)
Affinity DataKi:  14nMAssay Description:Inhibition of human cathepsin G using Suc-AAPF-MCA as substrate at pH 7.2 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520052(CHEMBL4554739)
Affinity DataKi:  19nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520058(CHEMBL4469390)
Affinity DataKi:  20nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520057(CHEMBL4441622)
Affinity DataKi:  37nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520055(CHEMBL4464900)
Affinity DataKi:  54nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520061(CHEMBL4556207)
Affinity DataKi:  54nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520050(CHEMBL4457132)
Affinity DataKi:  54nMAssay Description:Inhibition of human cathepsin G using Suc-AAPF-MCA as substrate at pH 7.2 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520053(CHEMBL4449838)
Affinity DataKi:  64nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520049(CHEMBL4560112)
Affinity DataKi:  150nMAssay Description:Inhibition of human cathepsin G using Suc-AAPF-MCA as substrate at pH 7.2 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B2(Homo sapiens)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520051(CHEMBL4592765)
Affinity DataKi:  150nMAssay Description:Inhibition of human chymotrypsin using Suc-AAPF-MCA as substrate at pH 8 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520060(CHEMBL4465306)
Affinity DataKi:  160nMAssay Description:Inhibition of human cathepsin G using Suc-AAPF-MCA as substrate at pH 7.2 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B2(Homo sapiens)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520049(CHEMBL4560112)
Affinity DataKi:  330nMAssay Description:Inhibition of human chymotrypsin using Suc-AAPF-MCA as substrate at pH 8 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50267001(CHEMBL4074776)
Affinity DataKi:  490nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50267000(CHEMBL4083086)
Affinity DataKi:  590nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520056(CHEMBL4462421)
Affinity DataKi:  740nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B2(Homo sapiens)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520061(CHEMBL4556207)
Affinity DataKi:  920nMAssay Description:Inhibition of human chymotrypsin using Suc-AAPF-MCA as substrate at pH 8 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520052(CHEMBL4554739)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of human cathepsin G using Suc-AAPF-MCA as substrate at pH 7.2 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B2(Homo sapiens)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520060(CHEMBL4465306)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of human chymotrypsin using Suc-AAPF-MCA as substrate at pH 8 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520065(CHEMBL4593335)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B2(Homo sapiens)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520050(CHEMBL4457132)
Affinity DataKi:  2.90E+3nMAssay Description:Inhibition of human chymotrypsin using Suc-AAPF-MCA as substrate at pH 8 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChromobox protein homolog 7(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50189696(CHEMBL3827924)
Affinity DataKi:  4.80E+3nMAssay Description:Binding affinity to CBX7ChD (7 to 66 residues) (unknown origin) expressed in RIPL-BL21 (DE3)-CodonPlus competent cells in presence of FITC-labeled SE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520061(CHEMBL4556207)
Affinity DataKi:  5.20E+3nMAssay Description:Inhibition of human cathepsin G using Suc-AAPF-MCA as substrate at pH 7.2 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChromobox protein homolog 7(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50189699(CHEMBL3827834)
Affinity DataKi:  1.00E+4nMAssay Description:Binding affinity to CBX7ChD (7 to 66 residues) (unknown origin) expressed in RIPL-BL21 (DE3)-CodonPlus competent cells in presence of FITC-labeled SE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChromobox protein homolog 7(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50189697(CHEMBL3827733)
Affinity DataKi:  1.00E+4nMAssay Description:Binding affinity to CBX7ChD (7 to 66 residues) (unknown origin) expressed in RIPL-BL21 (DE3)-CodonPlus competent cells in presence of FITC-labeled SE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChromobox protein homolog 7(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50189698(CHEMBL3827336)
Affinity DataKi:  1.69E+4nMAssay Description:Binding affinity to CBX7ChD (7 to 66 residues) (unknown origin) expressed in RIPL-BL21 (DE3)-CodonPlus competent cells in presence of FITC-labeled SE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChromobox protein homolog 7(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50189711(CHEMBL3827805)
Affinity DataKi:  2.50E+4nMAssay Description:Binding affinity to CBX7ChD (7 to 66 residues) (unknown origin) expressed in RIPL-BL21 (DE3)-CodonPlus competent cells in presence of FITC-labeled SE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChromobox protein homolog 7(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50189780(CHEMBL3827954)
Affinity DataKi:  3.31E+4nMAssay Description:Binding affinity to CBX7ChD (7 to 66 residues) (unknown origin) expressed in RIPL-BL21 (DE3)-CodonPlus competent cells in presence of FITC-labeled SE...More data for this Ligand-Target Pair
TargetChromobox protein homolog 7(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50189762(CHEMBL3827451)
Affinity DataKi:  3.93E+4nMAssay Description:Binding affinity to CBX7ChD (7 to 66 residues) (unknown origin) expressed in RIPL-BL21 (DE3)-CodonPlus competent cells in presence of FITC-labeled SE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
University Of California Riverside

LigandPNGBDBM60828(ABT-199 | BDBM189459 | US10213433, Compound 5 | US...)
Affinity DataIC50:  4.40nMAssay Description:One hundred microliters of a 600 ng/mL solution of biotin-BID (Biotin-lc-EDIIRNIARHLAQVGDSMDR-NH2, where lc indicates a hydrocarbon chain of six meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1 [1-149](Homo sapiens (Human))
University Of California Riverside

LigandPNGBDBM218788(Ac-CATQLRRFGDKLNFRQKLLN-NH2 | hNOXA)
Affinity DataIC50:  7.5nMAssay Description:One hundred microliters of a 600 ng/mL solution of biotin-BID (Biotin-lc-EDIIRNIARHLAQVGDSMDR-NH2, where lc indicates a hydrocarbon chain of six meth...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1 [1-149](Homo sapiens (Human))
University Of California Riverside

LigandPNGBDBM218795(130E7 | Ac-λIAQELRRIGDEFNAYYARR-NH2)
Affinity DataIC50:  8.70nMAssay Description:One hundred microliters of a 600 ng/mL solution of biotin-BID (Biotin-lc-EDIIRNIARHLAQVGDSMDR-NH2, where lc indicates a hydrocarbon chain of six meth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50520051(CHEMBL4592765)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells assessed as decrease in angiotensin 1 cleavage to angiotensin 2 incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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