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Found 184 with Last Name = 'yazawa' and Initial = 'k'
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Mitsui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067222(CHEMBL128906 | [6-(4-Carbamimidoyl-benzoylamino)-c...)
Affinity DataIC50:  0.0730nMAssay Description:Inhibition of Fibronogen binding to Immobilized Human Fibrinogen Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Mitsui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067216(CHEMBL129877 | {6-[4-(Imino-morpholin-4-yl-methyl)...)
Affinity DataIC50:  0.0980nMAssay Description:Inhibition of Fibronogen binding to Immobilized Human Fibrinogen Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Mitsui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067228(CHEMBL131823 | [7-(4-Carbamimidoyl-benzoylamino)-1...)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of Fibronogen binding to Immobilized Human Fibrinogen Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Mitsui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067217(CHEMBL323649 | {(S)-6-[4-(Imino-morpholin-4-yl-met...)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of Fibronogen binding to Immobilized Human Fibrinogen Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Mitsui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067224(CHEMBL130437 | {6-[4-(N-Prop-2-ynylcarbamimidoyl)-...)
Affinity DataIC50:  0.130nMAssay Description:Inhibition of Fibronogen binding to Immobilized Human Fibrinogen Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Mitsui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067220(CHEMBL130405 | {7-[4-(N-Propylcarbamimidoyl)-benzo...)
Affinity DataIC50:  0.130nMAssay Description:Inhibition of Fibronogen binding to Immobilized Human Fibrinogen Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Mitsui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067218(CHEMBL130878 | {7-[4-(Imino-morpholin-4-yl-methyl)...)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of Fibronogen binding to Immobilized Human Fibrinogen Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Mitsui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067223(CHEMBL130892 | {7-[4-(N-Prop-2-ynylcarbamimidoyl)-...)
Affinity DataIC50:  0.160nMAssay Description:Inhibition of Fibronogen binding to Immobilized Human Fibrinogen Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Mitsui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067227(CHEMBL128539 | {7-[4-(N-Furan-2-ylmethyl-carbamimi...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of Fibronogen binding to Immobilized Human Fibrinogen Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Mitsui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067230(CHEMBL131593 | {7-[4-(N-Allylcarbamimidoyl)-benzoy...)
Affinity DataIC50:  0.260nMAssay Description:Inhibition of Fibronogen binding to Immobilized Human Fibrinogen Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Mitsui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067226(CHEMBL335160 | {(R)-6-[4-(Imino-morpholin-4-yl-met...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of Fibronogen binding to Immobilized Human Fibrinogen Receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataIC50:  4nMAssay Description:Inhibition of PKCbeta2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50249539(5-((1S,2R)-2-aminocyclohexylamino)-7-(3,5-dimethox...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine--tRNA ligase(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50249539(5-((1S,2R)-2-aminocyclohexylamino)-7-(3,5-dimethox...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human SykMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50274756(CHEMBL459146 | cis-5-(2-Aminocyclohexylamino)-7-(3...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50274673(CHEMBL485204 | cis-5-(2-Aminocyclohexylamino)-7-(3...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine--tRNA ligase(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50249254(5-((1S,2R)-2-aminocyclohexylamino)-7-(3,5-dimethox...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human SykMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50249254(5-((1S,2R)-2-aminocyclohexylamino)-7-(3,5-dimethox...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine--tRNA ligase(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50249253(5-(2-Aminoethylamino)-7-(3,5-dimethoxyphenylamino)...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human SykMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine--tRNA ligase(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human SykMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataIC50:  18nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50274757(5-((1S,2R)-2-Aminocyclohexylamino)-7-(3,5-dimethox...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50274755(CHEMBL458973 | cis-5-(2-Aminocyclohexylamino)-7-(3...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50274712(CHEMBL515054 | cis-5-(2-Aminocyclohexylamino)-7-(3...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine--tRNA ligase(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50249319(2-(2-aminoethylamino)-4-(3-(trifluoromethyl)phenyl...)
Affinity DataIC50:  41nMAssay Description:Inhibition of human SykMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50274757(5-((1S,2R)-2-Aminocyclohexylamino)-7-(3,5-dimethox...)
Affinity DataIC50:  41nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26429((2E)-3-{4-[({8-carbamoyl-7-[(3,5-dimethoxyphenyl)a...)
Affinity DataIC50:  47nMpH: 7.6 T: 2°CAssay Description:A coupled spectrophotometric assay was used wherein ADP generated by ZAP-70 kinase was converted to ATP by pyruvate kinase (PK), with concomitant pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine--tRNA ligase(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50263121(CHEMBL472840 | cis-5-(2-Aminocyclohexylamino)-7-(3...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human SykMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataIC50:  53nMAssay Description:Inhibition of human ZAP70More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataIC50:  53nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine--tRNA ligase(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50263119(CHEMBL478642 | cis-5-(2-Aminocyclohexylamino)-7-(3...)
Affinity DataIC50:  83nMAssay Description:Inhibition of human SykMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26428(ethyl (2E)-3-{4-[({8-carbamoyl-7-[(3,5-dimethoxyph...)
Affinity DataIC50:  88nMpH: 7.6 T: 2°CAssay Description:A coupled spectrophotometric assay was used wherein ADP generated by ZAP-70 kinase was converted to ATP by pyruvate kinase (PK), with concomitant pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50274713(CHEMBL457519 | cis-5-(2-Aminocyclohexylamino)-7-(4...)
Affinity DataIC50:  92nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50263121(CHEMBL472840 | cis-5-(2-Aminocyclohexylamino)-7-(3...)
Affinity DataIC50:  97nMAssay Description:Inhibition of human ZAP70More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50263119(CHEMBL478642 | cis-5-(2-Aminocyclohexylamino)-7-(3...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human ZAP70More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine--tRNA ligase(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50263120(CHEMBL475882 | cis-5-(2-Aminocyclohexylamino)-7-(3...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human SykMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50249254(5-((1S,2R)-2-aminocyclohexylamino)-7-(3,5-dimethox...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human ZAP70More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50249254(5-((1S,2R)-2-aminocyclohexylamino)-7-(3,5-dimethox...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50263120(CHEMBL475882 | cis-5-(2-Aminocyclohexylamino)-7-(3...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human ZAP70More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26419(7-[(3,5-dimethoxyphenyl)amino]-5-{[(4-sulfamoylphe...)
Affinity DataIC50:  150nMpH: 7.6 T: 2°CAssay Description:A coupled spectrophotometric assay was used wherein ADP generated by ZAP-70 kinase was converted to ATP by pyruvate kinase (PK), with concomitant pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26415(5-{[(2,4-difluorophenyl)methyl]amino}-7-[(3,5-dime...)
Affinity DataIC50:  150nMpH: 7.6 T: 2°CAssay Description:A coupled spectrophotometric assay was used wherein ADP generated by ZAP-70 kinase was converted to ATP by pyruvate kinase (PK), with concomitant pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine--tRNA ligase(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50263040(5-(2-Amino-2-methylpropylamino)-7-(3,5-dimethoxyph...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human SykMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50274758(5-(2-Amino-2-methylpropylamino)-7-(3,5-dimethoxyph...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26422(4-[({8-carbamoyl-7-[(3,5-dimethoxyphenyl)amino]imi...)
Affinity DataIC50:  180nMpH: 7.6 T: 2°CAssay Description:A coupled spectrophotometric assay was used wherein ADP generated by ZAP-70 kinase was converted to ATP by pyruvate kinase (PK), with concomitant pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50249254(5-((1S,2R)-2-aminocyclohexylamino)-7-(3,5-dimethox...)
Affinity DataIC50:  180nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26420(7-[(3,5-dimethoxyphenyl)amino]-5-{[(4-methanesulfo...)
Affinity DataIC50:  190nMpH: 7.6 T: 2°CAssay Description:A coupled spectrophotometric assay was used wherein ADP generated by ZAP-70 kinase was converted to ATP by pyruvate kinase (PK), with concomitant pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26418(5-[(1H-1,3-benzodiazol-2-ylmethyl)amino]-7-[(3,5-d...)
Affinity DataIC50:  200nMpH: 7.6 T: 2°CAssay Description:A coupled spectrophotometric assay was used wherein ADP generated by ZAP-70 kinase was converted to ATP by pyruvate kinase (PK), with concomitant pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26410(7-[(3,5-dimethoxyphenyl)amino]-5-{[(4-fluorophenyl...)
Affinity DataIC50:  220nMpH: 7.6 T: 2°CAssay Description:A coupled spectrophotometric assay was used wherein ADP generated by ZAP-70 kinase was converted to ATP by pyruvate kinase (PK), with concomitant pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26404(5-[(2-aminoethyl)amino]-7-[(3,5-dimethoxyphenyl)am...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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