Compile Data Set for Download or QSAR
maximum 50k data
Found 2258 with Last Name = 'yoo' and Initial = 'j'
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50069294((S)-3-[4-(carbohydrazonamidol)-phenyl]-N-cyclopent...)
Affinity DataKi:  0.380nMAssay Description:Compound was tested for inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50069294((S)-3-[4-(carbohydrazonamidol)-phenyl]-N-cyclopent...)
Affinity DataKi:  0.380nMAssay Description:Binding affinity towards human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50069294((S)-3-[4-(carbohydrazonamidol)-phenyl]-N-cyclopent...)
Affinity DataKi:  1.10nMAssay Description:Compound was tested for inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50071729(CHEMBL313826 | Naphthalene-2-sulfonic acid [(S)-1-...)
Affinity DataKi:  3.10nMAssay Description:Binding affinity towards human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50071723((S)-3-(4-Aminomethyl-phenyl)-N-cyclopentyl-N-methy...)
Affinity DataKi:  3.30nMAssay Description:Binding affinity towards human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50069292(CHEMBL156082 | N-ethyl-N-cyclopentyl-3-(4-hydrazon...)
Affinity DataKi:  4nMAssay Description:Compound was tested for inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Mississippi

LigandPNGBDBM22741(1-(3,4-dimethylphenyl)-2-phenylethane-1,2-dione | ...)
Affinity DataKi:  4.10nM ΔG°:  -47.9kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Oryctolagus cuniculus (rabbit))
University of Mississippi

LigandPNGBDBM22733(1,2-bis(4-bromophenyl)ethane-1,2-dione | Benzil-ba...)
Affinity DataKi:  4.10nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50496304(CHEMBL3125712)
Affinity DataKi:  4.90nMAssay Description:Displacement of [125I]-I-AB-MECA from recombinant human adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Mississippi

LigandPNGBDBM22759(1-[4-(2-oxo-2-phenylacetyl)phenyl]-2-phenylethane-...)
Affinity DataKi:  5.60nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50071725((S)-3-(4-Aminomethyl-phenyl)-2-(anthracene-2-sulfo...)
Affinity DataKi:  5.70nMAssay Description:Binding affinity towards human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Oryctolagus cuniculus (rabbit))
University of Mississippi

LigandPNGBDBM22759(1-[4-(2-oxo-2-phenylacetyl)phenyl]-2-phenylethane-...)
Affinity DataKi:  6.10nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50071722((S)-3-(4-Aminomethyl-phenyl)-N-cyclopentyl-2-(6-me...)
Affinity DataKi:  6.60nMAssay Description:Binding affinity towards human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50496310(CHEMBL3125713)
Affinity DataKi:  6.70nMAssay Description:Displacement of [125I]-I-AB-MECA from recombinant human adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50070783((S)-3-(4-Carbamimidoyl-phenyl)-N-cyclopentyl-N-met...)
Affinity DataKi:  6.80nMAssay Description:Binding affinity towards human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50496311(CHEMBL3125718)
Affinity DataKi:  7.80nMAssay Description:Displacement of [125I]-I-AB-MECA from recombinant human adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Mississippi

LigandPNGBDBM22748(1-(4-methyl-3-nitrophenyl)-2-phenylethane-1,2-dion...)
Affinity DataKi:  7.90nM ΔG°:  -46.2kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
University of Mississippi

LigandPNGBDBM22759(1-[4-(2-oxo-2-phenylacetyl)phenyl]-2-phenylethane-...)
Affinity DataKi:  8nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50496307(CHEMBL3125717)
Affinity DataKi:  8.60nMAssay Description:Displacement of [125I]-I-AB-MECA from recombinant human adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Oryctolagus cuniculus (rabbit))
University of Mississippi

LigandPNGBDBM22747(1,2-bis(4-bromo-3-nitrophenyl)ethane-1,2-dione | B...)
Affinity DataKi:  8.70nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Mississippi

LigandPNGBDBM22745(1-(2-chlorophenyl)-2-(3,4-dimethoxyphenyl)ethane-1...)
Affinity DataKi:  8.90nM ΔG°:  -46.0kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50496308(CHEMBL3125714)
Affinity DataKi:  9.20nMAssay Description:Displacement of [125I]-I-AB-MECA from recombinant human adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Oryctolagus cuniculus (rabbit))
University of Mississippi

LigandPNGBDBM22731(1,2-bis(4-chlorophenyl)ethane-1,2-dione | Benzil-b...)
Affinity DataKi:  9.5nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50069055((S)-3-(4-Aminomethyl-phenyl)-N-cyclopentyl-N-methy...)
Affinity DataKi:  9.60nMAssay Description:Binding affinity towards human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50071726((S)-3-(4-Aminomethyl-phenyl)-N-cyclopentyl-N-methy...)
Affinity DataKi:  10nMAssay Description:Binding affinity towards human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Mississippi

LigandPNGBDBM22742(1-(4-methoxyphenyl)-2-phenylethane-1,2-dione | Ben...)
Affinity DataKi:  10.3nM ΔG°:  -45.6kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50071724((S)-3-(4-Aminomethyl-phenyl)-N-cyclopentyl-2-(5-di...)
Affinity DataKi:  11nMAssay Description:Binding affinity towards human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Rattus norvegicus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50496311(CHEMBL3125718)
Affinity DataKi:  11nMAssay Description:Displacement of [125I]-I-AB-MECA from rat adenosine A3 receptor expressed in RBL-2H3 cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Oryctolagus cuniculus (rabbit))
University of Mississippi

LigandPNGBDBM22748(1-(4-methyl-3-nitrophenyl)-2-phenylethane-1,2-dion...)
Affinity DataKi:  11.9nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50496305(CHEMBL3125716)
Affinity DataKi:  12nMAssay Description:Displacement of [125I]-I-AB-MECA from recombinant human adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Mississippi

LigandPNGBDBM22722(1,2-diphenylethane-1,2-dione | Benzil | CHEMBL1898...)
Affinity DataKi:  14.7nM ΔG°:  -44.7kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM22722(1,2-diphenylethane-1,2-dione | Benzil | CHEMBL1898...)
Affinity DataKi:  14.7nMAssay Description:Inhibition constant against human intestinal carboxylesterase (hiCE) expressed in Sf21 cells using 3 mM o-NPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Oryctolagus cuniculus (rabbit))
University of Mississippi

LigandPNGBDBM22746(1-[4-(bromomethyl)phenyl]-2-phenylethane-1,2-dione...)
Affinity DataKi:  15nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50496306(CHEMBL3125711)
Affinity DataKi:  16nMAssay Description:Displacement of [125I]-I-AB-MECA from recombinant human adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50496309(CHEMBL3125719)
Affinity DataKi:  16nMAssay Description:Displacement of [125I]-I-AB-MECA from recombinant human adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Oryctolagus cuniculus (rabbit))
University of Mississippi

LigandPNGBDBM22738(1-(4-chlorophenyl)-2-(4-methylphenyl)ethane-1,2-di...)
Affinity DataKi:  16.2nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Oryctolagus cuniculus (rabbit))
University of Mississippi

LigandPNGBDBM22734(1,2-bis(3,5-difluorophenyl)ethane-1,2-dione | Benz...)
Affinity DataKi:  17.5nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50069053((S)-3-(4-Aminomethyl-phenyl)-N-cyclopentyl-N-methy...)
Affinity DataKi:  18nMAssay Description:Binding affinity towards human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Mississippi

LigandPNGBDBM22737(1-(4-chlorophenyl)-2-phenylethane-1,2-dione | Benz...)
Affinity DataKi:  18.2nM ΔG°:  -44.2kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50071721((S)-3-(4-Aminomethyl-phenyl)-2-(4-cyclohexyl-benze...)
Affinity DataKi:  20nMAssay Description:Binding affinity towards human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Mississippi

LigandPNGBDBM22746(1-[4-(bromomethyl)phenyl]-2-phenylethane-1,2-dione...)
Affinity DataKi:  21.3nM ΔG°:  -43.8kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Oryctolagus cuniculus (rabbit))
University of Mississippi

LigandPNGBDBM22749(1-(4-nitrophenyl)-2-phenylethane-1,2-dione | Benzi...)
Affinity DataKi:  21.7nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Mississippi

LigandPNGBDBM22738(1-(4-chlorophenyl)-2-(4-methylphenyl)ethane-1,2-di...)
Affinity DataKi:  22.8nM ΔG°:  -43.6kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Mississippi

LigandPNGBDBM22734(1,2-bis(3,5-difluorophenyl)ethane-1,2-dione | Benz...)
Affinity DataKi:  23.4nM ΔG°:  -43.6kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Oryctolagus cuniculus (rabbit))
University of Mississippi

LigandPNGBDBM22737(1-(4-chlorophenyl)-2-phenylethane-1,2-dione | Benz...)
Affinity DataKi:  23.9nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Rattus norvegicus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50496305(CHEMBL3125716)
Affinity DataKi:  26nMAssay Description:Displacement of [125I]-I-AB-MECA from rat adenosine A3 receptor expressed in RBL-2H3 cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
University of Mississippi

LigandPNGBDBM50171925(1,2-Bis-(4-bromo-thiophen-2-yl)-ethane-1,2-dione |...)
Affinity DataKi:  30nMAssay Description:Inhibition constant against human liver carboxylesterase (hCE1) expressed in Sf21 cells using 3 mM o-NPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
University of Mississippi

LigandPNGBDBM50171925(1,2-Bis-(4-bromo-thiophen-2-yl)-ethane-1,2-dione |...)
Affinity DataKi:  30nMAssay Description:Inhibition constant against human liver carboxylesterase (hCE1) expressed in Sf21 cells using 3 mM o-NPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Mississippi

LigandPNGBDBM22749(1-(4-nitrophenyl)-2-phenylethane-1,2-dione | Benzi...)
Affinity DataKi:  30.6nM ΔG°:  -42.9kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Mississippi

LigandPNGBDBM22739(1-(4-methylphenyl)-2-phenylethane-1,2-dione | Benz...)
Affinity DataKi:  33.3nM ΔG°:  -42.7kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 2258 total ) | Next | Last >>
Jump to: