Affinity DataKi: 10nMAssay Description:Inhibitory activity against LTA 4 hydrolase in aminopeptidase assayMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Inhibitory activity against LTA 4 hydrolase in epoxide hydrolase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: <0.100nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Binding affinity towards alpha V/beta3 receptor by solid-phase receptor binding assays (SPRA)More data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Binding affinity towards alpha V-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.150nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Binding affinity towards alpha V/beta3 receptor by solid-phase receptor binding assays (SPRA)More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Binding affinity towards alpha V/beta3 receptor by solid-phase receptor binding assays (SPRA)More data for this Ligand-Target Pair
Affinity DataIC50: 0.270nMAssay Description:Binding affinity towards alpha V/beta3 receptor by solid-phase receptor binding assays (SPRA)More data for this Ligand-Target Pair
Affinity DataIC50: 0.310nMAssay Description:Binding affinity towards alpha V-beta1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.320nMAssay Description:Binding affinity towards alpha V/beta3 receptor by solid-phase receptor binding assays (SPRA)More data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMAssay Description:Binding affinity towards alpha V-beta1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.380nMAssay Description:Binding affinity towards alpha V-beta1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
University Of Texas Md Anderson Cancer Center
Curated by ChEMBL
University Of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human SHP2 assessed as downregulation of PERK level in human KYSE520 cells incubated for 2 hrs by Alpha screen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.410nMAssay Description:Binding affinity towards alpha V-beta5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.430nMAssay Description:Binding affinity towards alpha V/beta3 receptor by solid-phase receptor binding assays (SPRA)More data for this Ligand-Target Pair
Affinity DataIC50: 0.450nMAssay Description:Binding affinity towards alpha V-beta5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.460nMAssay Description:Binding affinity towards alpha V-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.470nMAssay Description:Binding affinity towards alpha V-beta5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.480nMAssay Description:Binding affinity towards alpha V-beta1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.490nMAssay Description:Binding affinity towards alpha V-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: <0.5nMAssay Description:Inhibition of human whole blood LTB-4 production (Leukotriene B-4).More data for this Ligand-Target Pair
Affinity DataIC50: 0.510nMAssay Description:Binding affinity towards alpha V-beta5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.520nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.530nMAssay Description:Binding affinity towards alpha V-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.630nMAssay Description:Binding affinity towards alpha V-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.630nMAssay Description:Binding affinity towards alpha V/beta3 receptor by solid-phase receptor binding assays (SPRA)More data for this Ligand-Target Pair
Affinity DataIC50: 0.680nMAssay Description:Binding affinity towards alpha IIb/beta3 integrin by solid-phase receptor binding assay (SPRA)More data for this Ligand-Target Pair
Affinity DataIC50: 0.690nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.710nMAssay Description:Binding affinity towards alpha IIb/beta3 integrin by solid-phase receptor binding assay (SPRA)More data for this Ligand-Target Pair
Affinity DataIC50: 0.760nMAssay Description:Binding affinity towards alpha V-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
University Of Texas Md Anderson Cancer Center
Curated by ChEMBL
University Of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Binding affinity towards alpha IIb/beta3 integrin by solid-phase receptor binding assay (SPRA)More data for this Ligand-Target Pair
Affinity DataIC50: 0.850nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.890nMAssay Description:Binding affinity towards alpha IIb/beta3 integrin by solid-phase receptor binding assay (SPRA)More data for this Ligand-Target Pair
Affinity DataIC50: 0.920nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.940nMAssay Description:Binding affinity towards alpha V/beta3 receptor by solid-phase receptor binding assays (SPRA)More data for this Ligand-Target Pair
Affinity DataIC50: 0.960nMAssay Description:Binding affinity towards alpha IIb/beta3 integrin by solid-phase receptor binding assay (SPRA)More data for this Ligand-Target Pair
Affinity DataIC50: 0.980nMAssay Description:Binding affinity towards alpha V/beta3 receptor by solid-phase receptor binding assays (SPRA)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
University Of Texas Md Anderson Cancer Center
Curated by ChEMBL
University Of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal his6-tagged wild type recombinant human SHP2 (1 to 597 residues) expressed in Escherichia coli BL21 (DE3) cells using fluoro...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of IDO1 in mouse Panc02 cells assessed as reduction in NFK level incubated for 48 hrs by RFMS analysisMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
University Of Texas Md Anderson Cancer Center
Curated by ChEMBL
University Of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
University Of Texas Md Anderson Cancer Center
Curated by ChEMBL
University Of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
University Of Texas Md Anderson Cancer Center
Curated by ChEMBL
University Of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human leukotriene A4 hydrolase (LTA-4).More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Binding affinity towards alpha IIb/beta3 integrin by solid-phase receptor binding assay (SPRA)More data for this Ligand-Target Pair