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Found 1098 with Last Name = 'zaczek' and Initial = 'r'
TargetCorticotropin-releasing factor receptor 1/2(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50219966(CHEMBL23959)
Affinity DataKi:  0.200nMAssay Description:In vitro binding affinity to the CRF receptor in rat cortical homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084878(Butyl-[8-(2,4-dichloro-phenyl)-2,7-dimethyl-pyrazo...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [125I]-tyrosine-ovine-CRF from human Corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1/2(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50219965(CHEMBL430913)
Affinity DataKi:  0.400nMAssay Description:In vitro binding affinity to the CRF receptor in rat cortical homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087713((1-Ethyl-propyl)-[3-(4-methoxy-2-methyl-phenyl)-2,...)
Affinity DataKi:  0.400nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50058163(Butyl-[2,5-dimethyl-7-(2,4,6-trimethyl-phenyl)-7H-...)
Affinity DataKi:  0.400nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1/2(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50220479(CHEMBL23342)
Affinity DataKi:  0.5nMAssay Description:In vitro binding affinity to the CRF receptor in rat cortical homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084876(CHEMBL344223 | [8-(2,4-Dichloro-phenyl)-2,7-dimeth...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [125I]-tyrosine-ovine-CRF from human Corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1/2(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50220478(CHEMBL22622)
Affinity DataKi:  0.600nMAssay Description:In vitro binding affinity to the CRF receptor in rat cortical homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1/2(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50219957(CHEMBL3085294)
Affinity DataKi:  0.600nMAssay Description:In vitro binding affinity to the CRF receptor in rat cortical homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1/2(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50219954(CHEMBL283993)
Affinity DataKi:  0.700nMAssay Description:In vitro binding affinity against Corticotropin releasing factor receptor in rat cortical homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1/2(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50219969(CHEMBL23439)
Affinity DataKi:  0.700nMAssay Description:In vitro binding affinity to the CRF receptor in rat cortical homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084880(CHEMBL140894 | Cyclopropylmethyl-[8-(2,4-dichloro-...)
Affinity DataKi:  0.700nMAssay Description:Displacement of [125I]-tyrosine-ovine-CRF from human Corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1/2(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50219962(CHEMBL431105)
Affinity DataKi:  0.700nMAssay Description:In vitro binding affinity against Corticotropin releasing factor receptor in rat cortical homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1/2(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50219962(CHEMBL431105)
Affinity DataKi:  0.740nMAssay Description:In vitro binding affinity to the CRF receptor in rat cortical homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1/2(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50220480(CHEMBL22433)
Affinity DataKi:  0.800nMAssay Description:In vitro binding affinity to the CRF receptor in rat cortical homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074509(CHEMBL354886 | [3-(2,4-Dibromo-phenyl)-5-methyl-3H...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074501(Butyl-ethyl-[2,5,6-trimethyl-7-(2,4,6-trimethyl-ph...)
Affinity DataKi:  0.840nMAssay Description:Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50476859(CHEMBL232938)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]succinamide from gamma secretase in THP1 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074492(CHEMBL168554 | [9-(2-Bromo-4-isopropyl-phenyl)-2,8...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1/2(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50219961(CHEMBL23483)
Affinity DataKi:  1nMAssay Description:In vitro binding affinity to the CRF receptor in rat cortical homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087713((1-Ethyl-propyl)-[3-(4-methoxy-2-methyl-phenyl)-2,...)
Affinity DataKi:  1nMAssay Description:Compound was tested for the binding affinity to human corticotropin releasing factor 1 (hCRF1) receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1/2(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50219967(CHEMBL423475)
Affinity DataKi:  1nMAssay Description:In vitro binding affinity to the CRF receptor in rat cortical homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1/2(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50220485(CHEMBL23354)
Affinity DataKi:  1nMAssay Description:In vitro binding affinity to the CRF receptor in rat cortical homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087713((1-Ethyl-propyl)-[3-(4-methoxy-2-methyl-phenyl)-2,...)
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087706(CHEMBL265847 | Urotensin-1-sucker fish(NDDPPISIDLT...)
Affinity DataKi:  1.07nMAssay Description:Binding affinity of the receptor corticotropin releasing factor receptor with peptidic agonistsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1/2(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50219963(CHEMBL276971)
Affinity DataKi:  1.10nMAssay Description:In vitro binding affinity to the CRF receptor in rat cortical homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084873(CHEMBL336678 | [8-(2,4-Dichloro-phenyl)-2,7-dimeth...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]-tyrosine-ovine-CRF from human Corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1/2(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50219963(CHEMBL276971)
Affinity DataKi:  1.10nMAssay Description:In vitro binding affinity against Corticotropin releasing factor receptor in rat cortical homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50476878(CHEMBL399204)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]succinamide from gamma secretase in THP1 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50058163(Butyl-[2,5-dimethyl-7-(2,4,6-trimethyl-phenyl)-7H-...)
Affinity DataKi:  1.20nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50476861(CHEMBL401044)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]succinamide from gamma secretase in THP1 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084877(CHEMBL140143 | [8-(2,4-Dichloro-phenyl)-2,7-dimeth...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [125I]-tyrosine-ovine-CRF from human Corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084869(CHEMBL337768 | [8-(2,4-Dichloro-phenyl)-2,7-dimeth...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [125I]-tyrosine-ovine-CRF from human Corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087706(CHEMBL265847 | Urotensin-1-sucker fish(NDDPPISIDLT...)
Affinity DataKi:  1.26nMAssay Description:Binding affinity of the receptor h-CRF2-alpha with peptidic agonistsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50206243(CHEMBL3918431)
Affinity DataKi:  1.30nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR expressed in HEK293 cell membranes incubated for 2 hrs and measured by gamma countin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087719(4-(5,7-Dichloro-2,3-dihydro-indol-1-yl)-1-(1-ethyl...)
Affinity DataKi:  1.30nMAssay Description:Compound was tested for the binding affinity to human corticotropin releasing factor 1 (hCRF1) receptors.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50476880(CHEMBL450279)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]succinamide from gamma secretase in THP1 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1/2(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50219970(CHEMBL23950)
Affinity DataKi:  1.30nMAssay Description:In vitro binding affinity to the CRF receptor in rat cortical homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM86190(CAS_0 | NSC_0 | hrCRF)
Affinity DataKi:  1.40nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1/2(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50219956(CHEMBL282289)
Affinity DataKi:  1.40nMAssay Description:In vitro binding affinity to the CRF receptor in rat cortical homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074465(CHEMBL354982 | [9-(2-Bromo-4-isopropyl-phenyl)-2-m...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50476871(CHEMBL232182)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]succinamide from gamma secretase in THP1 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1/2(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50219971(CHEMBL23291)
Affinity DataKi:  1.5nMAssay Description:In vitro binding affinity to the CRF receptor in rat cortical homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076602(CHEMBL368772 | [9-(2-Bromo-4-isopropyl-phenyl)-8-c...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]-TYR-oCRH as the displaced rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074500(3-(2-Bromo-4-isopropyl-phenyl)-7-(1-ethyl-pentylox...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076613(CHEMBL367253 | [9-(2-Bromo-4-isopropyl-phenyl)-8-m...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]-TYR-oCRH as the displaced rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084874(Butyl-[2,5-dimethyl-7-(2,4,6-trimethyl-phenyl)-7H-...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [125I]-tyrosine-ovine-CRF from human Corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084870(CHEMBL141085 | [8-(2,4-Dichloro-phenyl)-2,7-dimeth...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [125I]-tyrosine-ovine-CRF from human Corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084881(CHEMBL138154 | [8-(2,4-Dichloro-phenyl)-2,7-dimeth...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [125I]-tyrosine-ovine-CRF from human Corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50058163(Butyl-[2,5-dimethyl-7-(2,4,6-trimethyl-phenyl)-7H-...)
Affinity DataKi:  1.61nMAssay Description:Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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