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Found 93 with Last Name = 'zehra' and Initial = 'st'
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University of Karachi

LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  19nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University of Karachi

LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  32nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Canavalia ensiformis (Jack bean))
University of Karachi

LigandPNGBDBM152597(2-(1-(Benzofuran-2-yl)ethylidene)-N-(3-nitrophenyl...)
Affinity DataIC50:  77nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Canavalia ensiformis (Jack bean))
University of Karachi

LigandPNGBDBM152587(2-(1-(Benzofuran-2-yl)ethylidene)-N-phenylhydrazin...)
Affinity DataIC50:  89nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Canavalia ensiformis (Jack bean))
University of Karachi

LigandPNGBDBM152600(2-(1-(Benzofuran-2-yl)ethylidene)-N-(3-methoxyphen...)
Affinity DataIC50:  102nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Canavalia ensiformis (Jack bean))
University of Karachi

LigandPNGBDBM152591(2-(1-(Benzofuran-2-yl)ethylidene)-N-(4-fluoropheny...)
Affinity DataIC50:  177nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Canavalia ensiformis (Jack bean))
University of Karachi

LigandPNGBDBM152598(2-(1-(Benzofuran-2-yl)ethylidene)-N-(4-nitrophenyl...)
Affinity DataIC50:  181nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Canavalia ensiformis (Jack bean))
University of Karachi

LigandPNGBDBM57806(1-[1-(1-benzofuran-2-yl)ethylideneamino]-3-(3-meth...)
Affinity DataIC50:  283nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University of Karachi

LigandPNGBDBM175418(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50:  290nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Canavalia ensiformis (Jack bean))
University of Karachi

LigandPNGBDBM152602(2-(1-(Benzofuran-2-yl)ethylidene)-N-(2-methylpheny...)
Affinity DataIC50:  314nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Canavalia ensiformis (Jack bean))
University of Karachi

LigandPNGBDBM152593(2-(1-(Benzofuran-2-yl)ethylidene)-N-(2-fluoropheny...)
Affinity DataIC50:  321nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Canavalia ensiformis (Jack bean))
University of Karachi

LigandPNGBDBM152594(2-(1-(Benzofuran-2-yl)ethylidene)-N-(2,4-difluorop...)
Affinity DataIC50:  387nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University of Karachi

LigandPNGBDBM167896(3-(3′-Nitrophenyl)pyrido[2,3-b]pyrazine (6n))
Affinity DataIC50:  466nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Canavalia ensiformis (Jack bean))
University of Karachi

LigandPNGBDBM152596(2-(1-(Benzofuran-2-yl)ethylidene)-N-(2-bromophenyl...)
Affinity DataIC50:  564nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University of Karachi

LigandPNGBDBM167885(3-(3′-Methylphenyl)pyrido[2,3-b]pyrazine (6c...)
Affinity DataIC50:  583nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Canavalia ensiformis (Jack bean))
University of Karachi

LigandPNGBDBM152589(2-(1-(Benzofuran-2-yl)ethylidene)-N-(2,4-dichlorop...)
Affinity DataIC50:  592nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Canavalia ensiformis (Jack bean))
University of Karachi

LigandPNGBDBM152603(N-Allyl-2-(1-(benzofuran-2-yl)ethylidene)hydrazine...)
Affinity DataIC50:  694nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University of Karachi

LigandPNGBDBM167888(3-(3′-Fluorophenyl)pyrido[2,3-b]pyrazine (6f...)
Affinity DataIC50:  899nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Canavalia ensiformis (Jack bean))
University of Karachi

LigandPNGBDBM152588(2-(1-(Benzofuran-2-yl)ethylidene)-N-(3-chloropheny...)
Affinity DataIC50:  1.13E+3nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Canavalia ensiformis (Jack bean))
University of Karachi

LigandPNGBDBM152592(2-(1-(Benzofuran-2-yl)ethylidene)-N-(3-fluoropheny...)
Affinity DataIC50:  1.15E+3nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University of Karachi

LigandPNGBDBM167890(3-(3′-Chlorophenyl)pyrido[2,3-b]pyrazine (6h...)
Affinity DataIC50:  1.26E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University of Karachi

LigandPNGBDBM175410(2-[3-cyano-4,6-bis(3-methoxyphenyl)-6-methyl-1,2,5...)
Affinity DataIC50:  1.56E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University of Karachi

LigandPNGBDBM167896(3-(3′-Nitrophenyl)pyrido[2,3-b]pyrazine (6n))
Affinity DataIC50:  1.89E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University of Karachi

LigandPNGBDBM167895(3-(4′-Nitrophenyl)pyrido[2,3-b]pyrazine (6m))
Affinity DataIC50:  1.97E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Canavalia ensiformis (Jack bean))
University of Karachi

LigandPNGBDBM152590(2-(1-(Benzofuran-2-yl)ethylidene)-N-(2,5-dichlorop...)
Affinity DataIC50:  2.01E+3nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University of Karachi

LigandPNGBDBM175415(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50:  2.01E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University of Karachi

LigandPNGBDBM175416(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50:  2.32E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University of Karachi

LigandPNGBDBM167887(3-(4′-Fluorophenyl)pyrido[2,3-b]pyrazine (6e...)
Affinity DataIC50:  2.45E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University of Karachi

LigandPNGBDBM175419(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50:  2.45E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University of Karachi

LigandPNGBDBM167891(3-(2′-Chlorophenyl)pyrido[2,3-b]pyrazine (6i...)
Affinity DataIC50:  2.52E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University of Karachi

LigandPNGBDBM167889(3-(4′-Chlorophenyl)pyrido[2,3-b]pyrazine (6g...)
Affinity DataIC50:  2.59E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Canavalia ensiformis (Jack bean))
University of Karachi

LigandPNGBDBM152599(2-(1-(Benzofuran-2-yl)ethylidene)-N-(4-methoxyphen...)
Affinity DataIC50:  2.61E+3nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University of Karachi

LigandPNGBDBM167889(3-(4′-Chlorophenyl)pyrido[2,3-b]pyrazine (6g...)
Affinity DataIC50:  2.63E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University of Karachi

LigandPNGBDBM175416(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50:  2.78E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University of Karachi

LigandPNGBDBM167897(3-(2′-Nitrophenyl)pyrido[2,3-b]pyrazine (6o))
Affinity DataIC50:  3.00E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University of Karachi

LigandPNGBDBM167884(3-(4′-Methylphenyl)pyrido[2,3-b]pyrazine (6b...)
Affinity DataIC50:  3.06E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University of Karachi

LigandPNGBDBM167892(3-(3′-Bromophenyl)pyrido[2,3-b]pyrazine (6j))
Affinity DataIC50:  3.12E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Canavalia ensiformis (Jack bean))
University of Karachi

LigandPNGBDBM114552(1-[(E)-1-(1-benzofuran-2-yl)ethylideneamino]-3-(4-...)
Affinity DataIC50:  3.47E+3nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University of Karachi

LigandPNGBDBM167898(3-(4′-(Piperidin-1-yl)phenyl)pyrido[2,3-b]py...)
Affinity DataIC50:  3.91E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University of Karachi

LigandPNGBDBM167893(3-(2′-Bromophenyl)pyrido[2,3-b]pyrazine (6k))
Affinity DataIC50:  4.03E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University of Karachi

LigandPNGBDBM167894(3-(4′-Iodophenyl)pyrido[2,3-b]pyrazine (6l))
Affinity DataIC50:  4.05E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University of Karachi

LigandPNGBDBM175413(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50:  4.45E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University of Karachi

LigandPNGBDBM167898(3-(4′-(Piperidin-1-yl)phenyl)pyrido[2,3-b]py...)
Affinity DataIC50:  4.75E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University of Karachi

LigandPNGBDBM175417(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50:  5.11E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University of Karachi

LigandPNGBDBM175406(2-[3-cyano-6-methyl-4,6-bis(3-methylphenyl)-1,2,5,...)
Affinity DataIC50:  5.21E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University of Karachi

LigandPNGBDBM175411(2-[3-cyano-4,6-bis(4-hydroxyphenyl)-6-methyl-1,2,5...)
Affinity DataIC50:  5.38E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University of Karachi

LigandPNGBDBM167886(3-(2′-Methylphenyl)pyrido[2,3-b]pyrazine (6d...)
Affinity DataIC50:  5.39E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University of Karachi

LigandPNGBDBM167899(6,7,8,9-tetrahydropyrido[2,3-b]quinoxaline (6q))
Affinity DataIC50:  5.78E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University of Karachi

LigandPNGBDBM175413(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50:  5.87E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University of Karachi

LigandPNGBDBM167885(3-(3′-Methylphenyl)pyrido[2,3-b]pyrazine (6c...)
Affinity DataIC50:  5.88E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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