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Found 95 with Last Name = 'zhang' and Initial = 'hs'
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50314723(CHEMBL1090041 | endo-(S)-N-(4-fluorobenzyl)-4-(3-(...)
Affinity DataIC50:  14.4nMAssay Description:Antagonist activity at CCR5 receptor expressed in CHO cells assessed as inhibition of RANTES-induced [32S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50314722(CHEMBL1093331 | endo-(S)-methyl 4-(3-(2-methyl-3H-...)
Affinity DataIC50:  112nMAssay Description:Antagonist activity at CCR5 receptor expressed in CHO cells assessed as inhibition of RANTES-induced [32S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50321725(CHEMBL1170924 | endo-N-((S)-1-(4-(Trifluoromethyl)...)
Affinity DataIC50:  253nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-stimulated GTPgammaS binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479066(CHEMBL454190)
Affinity DataIC50: <400nMAssay Description:Inhibition of wild-type HIV1 integrase strand transfer activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479081(CHEMBL467149)
Affinity DataIC50: <400nMAssay Description:Inhibition of wild-type HIV1 integrase strand transfer activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479075(CHEMBL492770)
Affinity DataIC50: <400nMAssay Description:Inhibition of wild-type HIV1 integrase strand transfer activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479058(CHEMBL467380)
Affinity DataIC50:  600nMAssay Description:Inhibition of wild-type HIV1 integrase strand transfer activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479065(CHEMBL443890)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of wild-type HIV1 integrase strand transfer activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479064(CHEMBL452223)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of wild-type HIV1 integrase strand transfer activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479057(CHEMBL444974)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of wild-type HIV1 integrase strand transfer activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electropho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479067(CHEMBL452876)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of wild-type HIV1 integrase strand transfer activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479072(CHEMBL467361)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of wild-type HIV1 integrase strand transfer activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50321719(CHEMBL1172070 | Methyl-4-benzyl-1-((S)-3-(cyclobut...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-stimulated GTPgammaS binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50321720(CHEMBL1170738 | N-((S)-3-(4-benzyl-4-(hydroxymethy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-stimulated GTPgammaS binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50321723(CHEMBL1170925 | N-((S)-3-(4-(4-(N-benzyl-N-isoprop...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-stimulated GTPgammaS binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50321724(CHEMBL1170923 | endo-4-Fluoro-N-((S)-3-(3-(2-methy...)
Affinity DataIC50:  1.00E+4nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-stimulated GTPgammaS binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50321721(CHEMBL1170529 | Methyl-4-benzyl-1-((S)-3-(cyclobut...)
Affinity DataIC50:  1.00E+4nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-stimulated GTPgammaS binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50321722(CHEMBL1169745 | N-((S)-1-(4-(trifluoromethyl)pheny...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-stimulated GTPgammaS binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479048(CHEMBL476930)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of wild-type HIV1 integrase strand transfer activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479068(CHEMBL511423)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of wild-type HIV1 integrase strand transfer activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electropho...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479076(CHEMBL452111)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of wild-type HIV1 integrase strand transfer activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479056(CHEMBL448880)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of wild-type HIV1 integrase strand transfer activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479075(CHEMBL492770)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of wild-type HIV1 integrase 3'-processing activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electrophore...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479066(CHEMBL454190)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of wild-type HIV1 integrase 3'-processing activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electrophore...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479049(CHEMBL467389)
Affinity DataIC50:  2.42E+4nMAssay Description:Inhibition of wild-type HIV1 integrase strand transfer activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electropho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479053(CHEMBL464340)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of wild-type HIV1 integrase strand transfer activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479058(CHEMBL467380)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of wild-type HIV1 integrase 3'-processing activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electrophore...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479051(CHEMBL468234)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of wild-type HIV1 integrase strand transfer activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479052(CHEMBL468233)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of wild-type HIV1 integrase strand transfer activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479079(CHEMBL502238)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of wild-type HIV1 integrase strand transfer activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479108(CHEMBL512205)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of HIV1 wild type integrase strand transfer activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479080(CHEMBL467360)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of wild-type HIV1 integrase strand transfer activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479071(CHEMBL513666)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of wild-type HIV1 integrase strand transfer activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479055(CHEMBL469071)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of wild-type HIV1 integrase strand transfer activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479070(CHEMBL465864)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of wild-type HIV1 integrase strand transfer activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479060(CHEMBL469070)
Affinity DataIC50:  3.55E+4nMAssay Description:Inhibition of wild-type HIV1 integrase strand transfer activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479077(CHEMBL505776)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of wild-type HIV1 integrase strand transfer activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479050(CHEMBL468235)
Affinity DataIC50:  4.50E+4nMAssay Description:Inhibition of wild-type HIV1 integrase strand transfer activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electropho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479069(CHEMBL512106)
Affinity DataIC50:  5.30E+4nMAssay Description:Inhibition of wild-type HIV1 integrase strand transfer activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479074(CHEMBL467169)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibition of wild-type HIV1 integrase strand transfer activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479081(CHEMBL467149)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibition of wild-type HIV1 integrase 3'-processing activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electrophore...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479065(CHEMBL443890)
Affinity DataIC50:  5.60E+4nMAssay Description:Inhibition of wild-type HIV1 integrase 3'-processing activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electrophore...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479062(CHEMBL449221)
Affinity DataIC50:  5.80E+4nMAssay Description:Inhibition of wild-type HIV1 integrase strand transfer activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479112(CHEMBL458494)
Affinity DataIC50:  6.80E+4nMAssay Description:Inhibition of HIV1 wild type integrase strand transfer activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479107(CHEMBL455820)
Affinity DataIC50:  8.10E+4nMAssay Description:Inhibition of HIV1 wild type integrase strand transfer activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479073(CHEMBL467359)
Affinity DataIC50:  8.80E+4nMAssay Description:Inhibition of wild-type HIV1 integrase strand transfer activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479064(CHEMBL452223)
Affinity DataIC50:  9.10E+4nMAssay Description:Inhibition of wild-type HIV1 integrase 3'-processing activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electrophore...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479071(CHEMBL513666)
Affinity DataIC50:  9.20E+4nMAssay Description:Inhibition of wild-type HIV1 integrase 3'-processing activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electrophore...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479057(CHEMBL444974)
Affinity DataIC50:  9.40E+4nMAssay Description:Inhibition of wild-type HIV1 integrase 3'-processing activity using [32P]-labeled linear oligonucleotide substrate by polyacrylamide gel electrophore...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50479114(CHEMBL450074)
Affinity DataIC50:  9.70E+4nMAssay Description:Inhibition of HIV1 wild type integrase strand transfer activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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