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Found 19 with Last Name = 'zhang' and Initial = 'jt'
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Chinese Academy Of Medical Sciences And Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50470518(CHEMBL4294523)
Affinity DataKi:  740nMAssay Description:Inhibition of Cy5-labeled double-strand DNA probe binding to STAT3 (unknown origin) expressed in H1299 cell lysates assessed as decrease in DNA bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Chinese Academy Of Medical Sciences And Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50470513(CHEMBL4290712)
Affinity DataKi:  1.01E+3nMAssay Description:Inhibition of Cy5-labeled double-strand DNA probe binding to STAT3 (unknown origin) expressed in H1299 cell lysates assessed as decrease in DNA bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Chinese Academy Of Medical Sciences And Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50470517(CHEMBL4294114)
Affinity DataKi:  1.18E+3nMAssay Description:Inhibition of Cy5-labeled double-strand DNA probe binding to STAT3 (unknown origin) expressed in H1299 cell lysates assessed as decrease in DNA bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Chinese Academy Of Medical Sciences And Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50470512(CHEMBL1416382)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of Cy5-labeled double-strand DNA probe binding to STAT3 (unknown origin) expressed in H1299 cell lysates assessed as decrease in DNA bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50070208(A-65006 | AG-1749 | CHEBI:6375 | Lansoprazole | Pr...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of human FASN enoyl reductase activity using crotonyl CoA as substrate assessed as inhibition of substrate hydrolysis measured every 1 min...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Chinese Academy Of Medical Sciences And Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50470515(CHEMBL4291509)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of Cy5-labeled double-strand DNA probe binding to STAT3 (unknown origin) expressed in H1299 cell lysates assessed as decrease in DNA bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50241343((RS)-6-methoxy-2-((4-methoxy-3,5-dimethylpyridin-2...)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of purified recombinant FASN TE activity (unknown origin) using 4-MUH as substrate preincubated for 30 mins before substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Chinese Academy Of Medical Sciences And Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50470514(CHEMBL4283640)
Affinity DataKi:  3.92E+3nMAssay Description:Inhibition of Cy5-labeled double-strand DNA probe binding to STAT3 (unknown origin) expressed in H1299 cell lysates assessed as decrease in DNA bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50241342(5-(difluoromethoxy)-2-((3,4-dimethoxypyridin-2-yl)...)
Affinity DataKi:  4.10E+3nMAssay Description:Inhibition of purified recombinant FASN TE activity (unknown origin) using 4-MUH as substrate preincubated for 30 mins before substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50070208(A-65006 | AG-1749 | CHEBI:6375 | Lansoprazole | Pr...)
Affinity DataKi:  5.30E+3nMAssay Description:Inhibition of purified recombinant FASN TE activity (unknown origin) using 4-MUH as substrate preincubated for 30 mins before substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50070209(Aciphex | CHEBI:8768 | LY-307640 | Rabeprazole)
Affinity DataKi:  5.90E+3nMAssay Description:Inhibition of purified recombinant FASN TE activity (unknown origin) using 4-MUH as substrate preincubated for 30 mins before substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Chinese Academy Of Medical Sciences And Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50470516(CHEMBL4282824)
Affinity DataKi:  8.87E+3nMAssay Description:Inhibition of Cy5-labeled double-strand DNA probe binding to STAT3 (unknown origin) expressed in H1299 cell lysates assessed as decrease in DNA bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50241343((RS)-6-methoxy-2-((4-methoxy-3,5-dimethylpyridin-2...)
Affinity DataIC50:  2.96E+4nMAssay Description:Inhibition of purified recombinant FASN TE activity (unknown origin) using 4-MUH as substrate preincubated for 30 mins before substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50241342(5-(difluoromethoxy)-2-((3,4-dimethoxypyridin-2-yl)...)
Affinity DataIC50:  3.62E+4nMAssay Description:Inhibition of purified recombinant FASN TE activity (unknown origin) using 4-MUH as substrate preincubated for 30 mins before substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50070208(A-65006 | AG-1749 | CHEBI:6375 | Lansoprazole | Pr...)
Affinity DataIC50:  4.67E+4nMAssay Description:Inhibition of purified recombinant FASN TE activity (unknown origin) using 4-MUH as substrate preincubated for 30 mins before substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50070209(Aciphex | CHEBI:8768 | LY-307640 | Rabeprazole)
Affinity DataIC50:  5.20E+4nMAssay Description:Inhibition of purified recombinant FASN TE activity (unknown origin) using 4-MUH as substrate preincubated for 30 mins before substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50070208(A-65006 | AG-1749 | CHEBI:6375 | Lansoprazole | Pr...)
Affinity DataIC50:  9.30E+4nMAssay Description:Inhibition of FASN in human PANC1 cells assessed as inhibition of [14C]acetate incorporation preincubated for 4 hrs before [14C]acetate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50070208(A-65006 | AG-1749 | CHEBI:6375 | Lansoprazole | Pr...)
Affinity DataIC50:  1.24E+5nMAssay Description:Inhibition of FASN in human BxPC3 cells assessed as inhibition of [14C]acetate incorporation preincubated for 4 hrs before [14C]acetate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM24567((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)
Affinity DataIC50:  2.03E+5nMAssay Description:Inhibition of FASN in human PANC1 cells assessed as inhibition of [14C]acetate incorporation preincubated for 4 hrs before [14C]acetate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank