BindingDB PrimarySearch_ki

Found 140 with Last Name = 'zhang' and Initial = 'qw'

Alpha-1A adrenergic receptor(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)

Ki: 0.150nMAssay Description:Displacement of [3H]prazosin from alpha1-adrenoceptor (unknown origin) in cerebral cortex membranes after 60 mins by TopCount scintillation counting ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Purchase ChEBI
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Details Article PubMed DrugBank

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50151982(5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1...)

Ki: 0.200nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor (unknown origin) expressed in HEK293 cells membranes incubated for 60 mins by scintillation counti...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Purchase ChEBI
CHEMBL DrugBank MCE
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Details Article PubMed

5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50464861(CHEMBL4291322)

Ki: 0.260nMAssay Description:Displacement of [3H]LSD from recombinant human 5-HT7 receptor expressed in CHO cell membranes after 120 mins by TopCount scintillation counting metho...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Details Article PubMed

Sodium-dependent serotonin transporter(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50150105(CHEMBL124069 | [2-(6-Fluoro-chroman-8-yloxy)-ethyl...)

Ki: 0.470nMAssay Description:Inhibition of serotonin reuptake in SERT (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50464861(CHEMBL4291322)

Ki: 0.530nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HEK293 cell membranes after 60 mins by TopCount scintillation count...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50464857(CHEMBL4277476)

Ki: 0.550nMAssay Description:Displacement of [3H]LSD from recombinant human 5-HT7 receptor expressed in CHO cell membranes after 120 mins by TopCount scintillation counting metho...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50452368(CHEMBL4215605)

Ki: 0.75nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT7 receptor expressed in CHO cell membranes measured after 60 mins by scintillation counting metho...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50464863(CHEMBL4285796)

Ki: 0.790nMAssay Description:Displacement of [3H]LSD from recombinant human 5-HT7 receptor expressed in CHO cell membranes after 120 mins by TopCount scintillation counting metho...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50452370(CHEMBL4209430)

Ki: 0.840nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation count...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50529075(CHEMBL4544153)

Ki: 0.900nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHO cell membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50529074(CHEMBL4574299)

Ki: 0.990nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHO cell membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50464866(CHEMBL4278933)

Ki: 1.10nMAssay Description:Displacement of [3H]LSD from recombinant human 5-HT7 receptor expressed in CHO cell membranes after 120 mins by TopCount scintillation counting metho...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50464864(CHEMBL4286174)

Ki: 1.10nMAssay Description:Displacement of [3H]LSD from recombinant human 5-HT7 receptor expressed in CHO cell membranes after 120 mins by TopCount scintillation counting metho...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50452372(CHEMBL4204665)

Ki: 1.5nMAssay Description:Binding affinity to 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50452372(CHEMBL4204665)

Ki: 1.5nMAssay Description:Binding affinity to 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50529074(CHEMBL4574299)

Ki: 1.60nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor (unknown origin) expressed in HEK293 cells membranes incubated for 60 mins by scintillation counti...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50529069(CHEMBL4476294)

Ki: 1.60nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor (unknown origin) expressed in HEK293 cells membranes incubated for 60 mins by scintillation counti...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50464859(CHEMBL4289361)

Ki: 1.90nMAssay Description:Binding affinity to 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50529071(CHEMBL4471208)

Ki: 2nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHO cell membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50529069(CHEMBL4476294)

Ki: 2.20nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHO cell membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50464858(CHEMBL4294077)

Ki: 2.30nMAssay Description:Displacement of [3H]LSD from recombinant human 5-HT7 receptor expressed in CHO cell membranes after 120 mins by TopCount scintillation counting metho...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50452371(CHEMBL4217339)

Ki: 2.30nMAssay Description:Displacement of [3H]8-OH-DPAT from rat cerebral cortex 5-HT1A receptorMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50452366(CHEMBL4203932)

Ki: 2.40nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation count...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50464856(CHEMBL4288120)

Ki: 2.60nMAssay Description:Displacement of [3H]LSD from recombinant human 5-HT7 receptor expressed in CHO cell membranes after 120 mins by TopCount scintillation counting metho...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50118336(1-(5-Fluoro-benzo[b]thiophen-3-yl)-3-(4-quinolin-8...)

Ki: 2.70nMAssay Description:Displacement of [3H]8-OH-DPAT from rat frontal cortex 5-HT1A receptor measured after 15 minsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50452366(CHEMBL4203932)

Ki: 3.20nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT7 receptor expressed in CHO cell membranes measured after 60 mins by scintillation counting metho...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50464867(CHEMBL4289783)

Ki: 3.30nMAssay Description:Displacement of [3H]LSD from recombinant human 5-HT7 receptor expressed in CHO cell membranes after 120 mins by TopCount scintillation counting metho...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50464863(CHEMBL4285796)

Ki: 5.60nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HEK293 cell membranes after 60 mins by TopCount scintillation count...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50529075(CHEMBL4544153)

Ki: 6.30nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor (unknown origin) expressed in HEK293 cells membranes incubated for 60 mins by scintillation counti...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50452368(CHEMBL4215605)

Ki: 6.30nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation count...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50118336(1-(5-Fluoro-benzo[b]thiophen-3-yl)-3-(4-quinolin-8...)

Ki: 7.5nMAssay Description:Displacement of [3H]-paroxetine from rat cortical membranes measured after 60 minsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50464866(CHEMBL4278933)

Ki: 8.10nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HEK293 cell membranes after 60 mins by TopCount scintillation count...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50529071(CHEMBL4471208)

Ki: 8.40nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor (unknown origin) expressed in HEK293 cells membranes incubated for 60 mins by scintillation counti...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)

Ki: 9.5nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation count...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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Details Article PubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)

Ki: 9.5nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor (unknown origin) expressed in HEK293 cells membranes incubated for 60 mins by scintillation counti...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Purchase CHEMBL MCE
PC cid PC sid PDB Similars

Details Article PubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)

Ki: 9.5nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HEK293 cell membranes after 60 mins by TopCount scintillation count...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Purchase CHEMBL MCE
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Details Article PubMed

5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50529073(CHEMBL4543789)

Ki: 11nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHO cell membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50529072(CHEMBL4459410)

Ki: 11nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHO cell membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50464865(CHEMBL4289605)

Ki: 12nMAssay Description:Displacement of [3H]LSD from recombinant human 5-HT7 receptor expressed in CHO cell membranes after 120 mins by TopCount scintillation counting metho...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50452370(CHEMBL4209430)

Ki: 12nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT7 receptor expressed in CHO cell membranes measured after 60 mins by scintillation counting metho...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Details Article PubMed

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50452371(CHEMBL4217339)

Ki: 12nMAssay Description:Displacement of [3H]-paroxetine from rat cerebral cortex SERTMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50464864(CHEMBL4286174)

Ki: 13nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HEK293 cell membranes after 60 mins by TopCount scintillation count...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50529073(CHEMBL4543789)

Ki: 15nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor (unknown origin) expressed in HEK293 cells membranes incubated for 60 mins by scintillation counti...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50464856(CHEMBL4288120)

Ki: 15nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HEK293 cell membranes after 60 mins by TopCount scintillation count...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50464857(CHEMBL4277476)

Ki: 18nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HEK293 cell membranes after 60 mins by TopCount scintillation count...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

Sodium-dependent serotonin transporter(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50464859(CHEMBL4289361)

Ki: 25nMAssay Description:Inhibition of serotonin reuptake in SERT (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50464858(CHEMBL4294077)

Ki: 25nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HEK293 cell membranes after 60 mins by TopCount scintillation count...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)

Ki: 26nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT7 receptor expressed in CHO cell membranes measured after 60 mins by scintillation counting metho...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Purchase CHEMBL MCE
PC cid PC sid PDB Similars

Details Article PubMed

5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)

Ki: 26nMAssay Description:Displacement of [3H]LSD from recombinant human 5-HT7 receptor expressed in CHO cell membranes after 120 mins by TopCount scintillation counting metho...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Purchase CHEMBL MCE
PC cid PC sid PDB Similars

Details Article PubMed

5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL

PNG

BDBM50400902(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)

Ki: 26nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHO cell membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Purchase CHEMBL MCE
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Details Article PubMed

Displayed 1 to 50 (of 140 total ) | Next | Last >>

Filter my 140 hits

Targets 13▿
- Sodium-dependent serotonin transporter 43
- 5-hydroxytryptamine receptor 1A 30
- 5-hydroxytryptamine receptor 7 24
- Mitogen-activated protein kinase kinase kinase 20 18
- Serine/threonine-protein kinase B-raf 16
- Alpha-1A adrenergic receptor 2
- Mast/stem cell growth factor receptor Kit 1
- Dual specificity mitogen-activated protein kinase kinase 5 1
- Serine/threonine-protein kinase SIK1 1
- Aurora kinase B 1
- Tyrosine-protein kinase FRK 1
- Potassium voltage-gated channel subfamily H member 2 1
- Tyrosine-protein kinase Srms 1
- ...
Publications 4▿
- Eur J Med Chem 144: 701-715 (2018) 46
- J Med Chem 60: 5927-5932 (2017) 40
- Bioorg Med Chem Lett 29: (2019) 33
- Bioorg Med Chem Lett 27: 5420-5423 (2017) 21
Institutions 3▿
- Shanghai Institute Of Pharmaceutical Industry 67
- University Of Macau 40
- China State Institute Of Pharmaceutical Industry 33
Affinity: 0.15 to 3.0E+4 nM▿
- Ki 57
- IC50 74
- Kd 7
- EC50 2
- Affinity ≤ nM
Xtal structures: 4
Docked structures: 0
Catalog Cmpds: 6