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Found 62 with Last Name = 'zhang' and Initial = 'xm'
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50350681(CHEMBL1813771)
Affinity DataIC50:  50nMAssay Description:Inhibition of iNOS in mouse RAW264.7 cells assessed as conversion of L-citrulline to L-arginine incubated for 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50350680(CHEMBL1813770)
Affinity DataIC50:  90nMAssay Description:Inhibition of iNOS in mouse RAW264.7 cells assessed as conversion of L-citrulline to L-arginine incubated for 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50350683(CHEMBL1813764)
Affinity DataIC50:  100nMAssay Description:Inhibition of iNOS in mouse RAW264.7 cells assessed as conversion of L-citrulline to L-arginine incubated for 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50350684(CHEMBL1813769)
Affinity DataIC50:  120nMAssay Description:Inhibition of iNOS in mouse RAW264.7 cells assessed as conversion of L-citrulline to L-arginine incubated for 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50357377(CHEMBL1917268)
Affinity DataIC50:  1.27E+3nMAssay Description:Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50357380(CHEMBL1917271)
Affinity DataIC50:  1.66E+3nMAssay Description:Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50357385(CHEMBL1917276)
Affinity DataIC50:  1.83E+3nMAssay Description:Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50350682(CHEMBL1813925)
Affinity DataIC50:  2.02E+3nMAssay Description:Inhibition of iNOS in mouse RAW264.7 cells assessed as conversion of L-citrulline to L-arginine incubated for 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50357378(CHEMBL1917269)
Affinity DataIC50:  2.02E+3nMAssay Description:Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50350685(CHEMBL1813926)
Affinity DataIC50:  2.16E+3nMAssay Description:Inhibition of iNOS in mouse RAW264.7 cells assessed as conversion of L-citrulline to L-arginine incubated for 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50330811(2-Chloro-5-[[(5-(o-hydroxyl-p-methoxyphenyl)-1,3,4...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of telomerase in human SGC7901 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50357382(CHEMBL1917273)
Affinity DataIC50:  2.34E+3nMAssay Description:Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50350686(CHEMBL1813773)
Affinity DataIC50:  2.35E+3nMAssay Description:Inhibition of iNOS in mouse RAW264.7 cells assessed as conversion of L-citrulline to L-arginine incubated for 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50357384(CHEMBL1917275)
Affinity DataIC50:  2.44E+3nMAssay Description:Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50357379(CHEMBL1917270)
Affinity DataIC50:  2.45E+3nMAssay Description:Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50105463(2,7-diamino-10-ethyl-9-phenylphenanthridinium brom...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of telomerase in human SGC7901 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50357369(CHEMBL1917260)
Affinity DataIC50:  2.71E+3nMAssay Description:Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50357375(CHEMBL1917266)
Affinity DataIC50:  2.91E+3nMAssay Description:Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50357370(CHEMBL1917261)
Affinity DataIC50:  2.93E+3nMAssay Description:Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50357368(CHEMBL1917259)
Affinity DataIC50:  3.26E+3nMAssay Description:Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50357376(CHEMBL1917267)
Affinity DataIC50:  3.66E+3nMAssay Description:Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50357373(CHEMBL1917264)
Affinity DataIC50:  3.67E+3nMAssay Description:Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50330812(2-Chloro-5-[[(5-(naphth-1-yl)-1,3,4-oxadiazol-2-yl...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of telomerase in human SGC7901 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50357374(CHEMBL1917265)
Affinity DataIC50:  4.65E+3nMAssay Description:Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50357372(CHEMBL1917263)
Affinity DataIC50:  5.04E+3nMAssay Description:Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50357381(CHEMBL1917272)
Affinity DataIC50:  5.89E+3nMAssay Description:Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50357367(CHEMBL1917258)
Affinity DataIC50:  8.21E+3nMAssay Description:Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataIC50:  8.32E+3nMAssay Description:Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50357371(CHEMBL1917262)
Affinity DataIC50:  1.22E+4nMAssay Description:Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50357383(CHEMBL1917274)
Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50034110(CHEMBL15060 | Melatonin,2-Phenyl | N-[2-(5-Methoxy...)
Affinity DataEC50:  7.00E+3nMAssay Description:Agonist activity at human MT2 receptor transfected in HEK293T cells co-transfected with tet-inducible luciferase reporter plasmid, pCDNA3.1(+)-CMV-be...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50591560(CHEMBL5186032)
Affinity DataEC50:  2.99E+5nMAssay Description:Agonist activity at human MT2 receptor transfected in HEK293T cells co-transfected with tet-inducible luciferase reporter plasmid, pCDNA3.1(+)-CMV-be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50035179(Agomelatine | CHEMBL10878 | N-[2-(7-Methoxy-naphth...)
Affinity DataEC50:  2.65E+4nMAssay Description:Agonist activity at human MT1 receptor transfected in HEK293T cells co-transfected with tet-inducible luciferase reporter plasmid, pCDNA3.1(+)-CMV-be...More data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50034110(CHEMBL15060 | Melatonin,2-Phenyl | N-[2-(5-Methoxy...)
Affinity DataEC50:  1.65E+4nMAssay Description:Agonist activity at human MT1 receptor transfected in HEK293T cells co-transfected with tet-inducible luciferase reporter plasmid, pCDNA3.1(+)-CMV-be...More data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50591560(CHEMBL5186032)
Affinity DataEC50:  2.10E+4nMAssay Description:Agonist activity at human MT1 receptor transfected in HEK293T cells co-transfected with tet-inducible luciferase reporter plasmid, pCDNA3.1(+)-CMV-be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50591563(CHEMBL5209421)
Affinity DataEC50:  4.30E+5nMAssay Description:Agonist activity at human MT2 receptor expressed in HEK293 cells by Fluo-8 based calcium assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50035179(Agomelatine | CHEMBL10878 | N-[2-(7-Methoxy-naphth...)
Affinity DataEC50:  1.73E+7nMAssay Description:Agonist activity at human MT2 receptor expressed in HEK293 cells by Fluo-8 based calcium assayMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetMelatonin receptor type 1B(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50591562(CHEMBL5204811)
Affinity DataEC50:  2.70E+5nMAssay Description:Agonist activity at human MT2 receptor expressed in HEK293 cells by Fluo-8 based calcium assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50591561(CHEMBL5178098)
Affinity DataEC50:  3.80E+5nMAssay Description:Agonist activity at human MT2 receptor expressed in HEK293 cells by Fluo-8 based calcium assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50591560(CHEMBL5186032)
Affinity DataEC50:  2.60E+5nMAssay Description:Agonist activity at human MT2 receptor expressed in HEK293 cells by Fluo-8 based calcium assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50591559(CHEMBL5179507)
Affinity DataEC50:  3.50E+5nMAssay Description:Agonist activity at human MT2 receptor expressed in HEK293 cells by Fluo-8 based calcium assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50591558(CHEMBL5207850)
Affinity DataEC50:  3.60E+5nMAssay Description:Agonist activity at human MT2 receptor expressed in HEK293 cells by Fluo-8 based calcium assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50591557(CHEMBL5195549)
Affinity DataEC50:  1.30E+5nMAssay Description:Agonist activity at human MT2 receptor expressed in HEK293 cells by Fluo-8 based calcium assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50591556(CHEMBL5202288)
Affinity DataEC50:  3.50E+5nMAssay Description:Agonist activity at human MT2 receptor expressed in HEK293 cells by Fluo-8 based calcium assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50591555(CHEMBL5189446)
Affinity DataEC50:  5.20E+5nMAssay Description:Agonist activity at human MT2 receptor expressed in HEK293 cells by Fluo-8 based calcium assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50591563(CHEMBL5209421)
Affinity DataEC50:  4.20E+5nMAssay Description:Agonist activity at human MT1 receptor expressed in HEK293 cells by Fluo-8 based calcium assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50035179(Agomelatine | CHEMBL10878 | N-[2-(7-Methoxy-naphth...)
Affinity DataEC50:  5.80E+6nMAssay Description:Agonist activity at human MT1 receptor expressed in HEK293 cells by Fluo-8 based calcium assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50591562(CHEMBL5204811)
Affinity DataEC50:  3.80E+5nMAssay Description:Agonist activity at human MT1 receptor expressed in HEK293 cells by Fluo-8 based calcium assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50591561(CHEMBL5178098)
Affinity DataEC50:  4.60E+5nMAssay Description:Agonist activity at human MT1 receptor expressed in HEK293 cells by Fluo-8 based calcium assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50591560(CHEMBL5186032)
Affinity DataEC50:  3.30E+5nMAssay Description:Agonist activity at human MT1 receptor expressed in HEK293 cells by Fluo-8 based calcium assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
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