Compile Data Set for Download or QSAR
maximum 50k data
Found 143 with Last Name = 'zhang' and Initial = 'yj'
TargetChitinase(Ostrinia furnacalis)
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50514507(CHEMBL1583158)
Affinity DataKi:  9nMAssay Description:Inhibition of Ostrinia furnacalis chitinase h catalytic domain overexpressed in Pichia pastoris using 4MU-(GlcNAc)2 as substrate after 30 mins by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitotriosidase-1(Mus musculus)
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50514508(CHEMBL4549449)
Affinity DataKi:  35nMAssay Description:Inhibition of mouse CHIT1 catalytic domain overexpressed in Pichia pastoris using 4MU-(GlcNAc)2 as substrate after 30 mins by fluorescence based micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitotriosidase-1(Homo sapiens (Human))
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50514508(CHEMBL4549449)
Affinity DataKi:  49nMAssay Description:Inhibition of human CHIT1 catalytic domain overexpressed in Pichia pastoris using 4MU-(GlcNAc)2 as substrate after 30 mins by fluorescence based micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase B(Serratia marcescens)
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50514507(CHEMBL1583158)
Affinity DataKi:  58nMAssay Description:Inhibition of Serratia marcescens chitinase b catalytic domain overexpressed in Escherichia coli BL21(DE3) cells using 4MU-(GlcNAc)2 as substrate aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase(Ostrinia furnacalis)
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50514508(CHEMBL4549449)
Affinity DataKi:  390nMAssay Description:Inhibition of Ostrinia furnacalis chitinase h catalytic domain overexpressed in Pichia pastoris using 4MU-(GlcNAc)2 as substrate after 30 mins by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitinase B(Serratia marcescens)
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50514508(CHEMBL4549449)
Affinity DataKi:  410nMAssay Description:Inhibition of Serratia marcescens chitinase b catalytic domain overexpressed in Escherichia coli BL21(DE3) cells using 4MU-(GlcNAc)2 as substrate aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcidic mammalian chitinase(Mus musculus)
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50514508(CHEMBL4549449)
Affinity DataKi:  510nMAssay Description:Inhibition of mouse acidic mammalian chitinase catalytic domain overexpressed in Pichia pastoris using 4MU-(GlcNAc)2 as substrate after 30 mins by fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitotriosidase-1(Homo sapiens (Human))
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50514507(CHEMBL1583158)
Affinity DataKi:  1.12E+3nMAssay Description:Inhibition of human CHIT1 catalytic domain overexpressed in Pichia pastoris using 4MU-(GlcNAc)2 as substrate after 30 mins by fluorescence based micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcidic mammalian chitinase(Mus musculus)
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50514507(CHEMBL1583158)
Affinity DataKi:  1.38E+3nMAssay Description:Inhibition of mouse acidic mammalian chitinase catalytic domain overexpressed in Pichia pastoris using 4MU-(GlcNAc)2 as substrate after 30 mins by fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitotriosidase-1(Mus musculus)
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50514507(CHEMBL1583158)
Affinity DataKi:  1.94E+3nMAssay Description:Inhibition of mouse CHIT1 catalytic domain overexpressed in Pichia pastoris using 4MU-(GlcNAc)2 as substrate after 30 mins by fluorescence based micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcidic mammalian chitinase(Homo sapiens (Human))
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50514508(CHEMBL4549449)
Affinity DataKi:  3.96E+3nMAssay Description:Inhibition of human acidic mammalian chitinase catalytic domain overexpressed in Pichia pastoris using 4MU-(GlcNAc)2 as substrate after 30 mins by fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcidic mammalian chitinase(Homo sapiens (Human))
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50514507(CHEMBL1583158)
Affinity DataKi:  9.72E+3nMAssay Description:Inhibition of human acidic mammalian chitinase catalytic domain overexpressed in Pichia pastoris using 4MU-(GlcNAc)2 as substrate after 30 mins by fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  130nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
TargetNADP-dependent malic enzyme(Homo sapiens (Human))
Cytrx Laboratories

Curated by ChEMBL
LigandPNGBDBM50177180(3-(4-(4-hydroxyphenyl)piperazin-1-yl)-1-phenylpyrr...)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity against cytosolic malic enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50461196(CHEMBL4228405)
Affinity DataIC50:  180nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Riken Center For Life Science Technologies

LigandPNGBDBM227634(MTH1 inhibitor, 121)
Affinity DataIC50:  210nMpH: 7.5Assay Description:Enzymatic reaction was initiated by adding either 8-oxo-dGTP (13.2 μm; TriLink BioTechnologies) or 2-OH-dATP (8.3 μm; Jena Bioscience) to r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Riken Center For Life Science Technologies

LigandPNGBDBM227638(MTH1 inhibitor, 132)
Affinity DataIC50:  230nMpH: 7.5Assay Description:Enzymatic reaction was initiated by adding either 8-oxo-dGTP (13.2 μm; TriLink BioTechnologies) or 2-OH-dATP (8.3 μm; Jena Bioscience) to r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Riken Center For Life Science Technologies

LigandPNGBDBM227638(MTH1 inhibitor, 132)
Affinity DataIC50:  350nMpH: 7.5Assay Description:Enzymatic reaction was initiated by adding either 8-oxo-dGTP (13.2 μm; TriLink BioTechnologies) or 2-OH-dATP (8.3 μm; Jena Bioscience) to r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Riken Center For Life Science Technologies

LigandPNGBDBM227634(MTH1 inhibitor, 121)
Affinity DataIC50:  420nMpH: 7.5Assay Description:Enzymatic reaction was initiated by adding either 8-oxo-dGTP (13.2 μm; TriLink BioTechnologies) or 2-OH-dATP (8.3 μm; Jena Bioscience) to r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADP-dependent malic enzyme(Homo sapiens (Human))
Cytrx Laboratories

Curated by ChEMBL
LigandPNGBDBM50177175(1-benzyl-3-(4-(4-hydroxyphenyl)piperazin-1-yl)-1-p...)
Affinity DataIC50:  450nMAssay Description:Inhibitory activity against cytosolic malic enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50461206(CHEMBL4225898)
Affinity DataIC50:  460nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNADP-dependent malic enzyme(Homo sapiens (Human))
Cytrx Laboratories

Curated by ChEMBL
LigandPNGBDBM50177184(1-(3-chloro-4-methylphenyl)3-(4-(4-hydroxyphenyl)p...)
Affinity DataIC50:  560nMAssay Description:Inhibitory activity against cytosolic malic enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Riken Center For Life Science Technologies

LigandPNGBDBM227632(MTH1 inhibitor, 53)
Affinity DataIC50:  630nMpH: 7.5Assay Description:Enzymatic reaction was initiated by adding either 8-oxo-dGTP (13.2 μm; TriLink BioTechnologies) or 2-OH-dATP (8.3 μm; Jena Bioscience) to r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50461204(CHEMBL4227576)
Affinity DataIC50:  750nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50461197(CHEMBL4226687)
Affinity DataIC50:  810nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50461198(CHEMBL4225848)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Riken Center For Life Science Technologies

LigandPNGBDBM227632(MTH1 inhibitor, 53)
Affinity DataIC50:  1.13E+3nMpH: 7.5Assay Description:Enzymatic reaction was initiated by adding either 8-oxo-dGTP (13.2 μm; TriLink BioTechnologies) or 2-OH-dATP (8.3 μm; Jena Bioscience) to r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50461205(CHEMBL4225048)
Affinity DataIC50:  1.14E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50461194(CHEMBL4228935)
Affinity DataIC50:  1.57E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Zhejiang University of Technology

LigandPNGBDBM206322(2-(4-chlorophenyl)-6-((4-(((4-fluorophenyl)amino)m...)
Affinity DataIC50:  1.60E+3nMAssay Description:The inhibitory activities of flavones were determined in vitroby using fluorescent probe method following the general proceduredescribed in the liter...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Riken Center For Life Science Technologies

LigandPNGBDBM227636(MTH1 inhibitor, 123)
Affinity DataIC50:  1.90E+3nMpH: 7.5Assay Description:Enzymatic reaction was initiated by adding either 8-oxo-dGTP (13.2 μm; TriLink BioTechnologies) or 2-OH-dATP (8.3 μm; Jena Bioscience) to r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Zhejiang University of Technology

LigandPNGBDBM206322(2-(4-chlorophenyl)-6-((4-(((4-fluorophenyl)amino)m...)
Affinity DataIC50:  2.10E+3nMAssay Description:The inhibitory activities of flavones were determined in vitroby using fluorescent probe method following the general proceduredescribed in the liter...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50461200(CHEMBL4225322)
Affinity DataIC50:  2.11E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50461192(CHEMBL4225380)
Affinity DataIC50:  2.61E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50461191(CHEMBL4228262)
Affinity DataIC50:  2.78E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Riken Center For Life Science Technologies

LigandPNGBDBM227631(MTH1 inhibitor, 14)
Affinity DataIC50:  2.80E+3nMpH: 7.5Assay Description:Enzymatic reaction was initiated by adding either 8-oxo-dGTP (13.2 μm; TriLink BioTechnologies) or 2-OH-dATP (8.3 μm; Jena Bioscience) to r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Riken Center For Life Science Technologies

LigandPNGBDBM227636(MTH1 inhibitor, 123)
Affinity DataIC50:  2.80E+3nMpH: 7.5Assay Description:Enzymatic reaction was initiated by adding either 8-oxo-dGTP (13.2 μm; TriLink BioTechnologies) or 2-OH-dATP (8.3 μm; Jena Bioscience) to r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50461195(CHEMBL4227837)
Affinity DataIC50:  3.04E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNADP-dependent malic enzyme(Homo sapiens (Human))
Cytrx Laboratories

Curated by ChEMBL
LigandPNGBDBM50177177(1-phenyl-3-(4-(3-(trifluoromethyl)phenyl)piperazin...)
Affinity DataIC50:  3.15E+3nMAssay Description:Inhibitory activity against cytosolic malic enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50461207(CHEMBL4227439)
Affinity DataIC50:  3.52E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Riken Center For Life Science Technologies

LigandPNGBDBM227631(MTH1 inhibitor, 14)
Affinity DataIC50:  3.90E+3nMpH: 7.5Assay Description:Enzymatic reaction was initiated by adding either 8-oxo-dGTP (13.2 μm; TriLink BioTechnologies) or 2-OH-dATP (8.3 μm; Jena Bioscience) to r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50461209(CHEMBL4225407)
Affinity DataIC50:  4.11E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Riken Center For Life Science Technologies

LigandPNGBDBM227635(MTH1 inhibitor, 122)
Affinity DataIC50:  4.80E+3nMpH: 7.5Assay Description:Enzymatic reaction was initiated by adding either 8-oxo-dGTP (13.2 μm; TriLink BioTechnologies) or 2-OH-dATP (8.3 μm; Jena Bioscience) to r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50461208(CHEMBL4228094)
Affinity DataIC50:  4.94E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50461203(CHEMBL4228205)
Affinity DataIC50:  5.22E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50461190(CHEMBL4226417)
Affinity DataIC50:  5.27E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50461199(CHEMBL4226162)
Affinity DataIC50:  5.32E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50461201(CHEMBL4228325)
Affinity DataIC50:  5.72E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Mus musculus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50461202(CHEMBL4228289)
Affinity DataIC50:  6.57E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50351999(CHEMBL1822607)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in CHO cells assessed as p-nitorphenol production after 2 mins by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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