BindingDB PrimarySearch_ki

Found 362 with Last Name = 'zhang-hoover' and Initial = 'j'

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM50560327(CHEMBL4749037)

IC50: 0.0830nMAssay Description:Inhibition of recombinant full length BTK (unknown origin) expressed in baculovirus infected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-NH2 peptide as su...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM288531((1R,3R,5S,6r)-3-[8- amino-1-(4-{[4- (trifluorometh...)

IC50: 0.100nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM50233382(CHEMBL4074833)

IC50: 0.100nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM288463(4-(8-amino-1-(2- fluoro-4-((4- (trifluoromethyl) p...)

IC50: 0.100nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM255290(US9481682, 39)

IC50: 0.100nMAssay Description:Inhibition of recombinant full length BTK (unknown origin) expressed in baculovirus infected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-NH2 peptide as su...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM255256(US9481682, 4)

IC50: 0.100nMAssay Description:Inhibition of recombinant full length BTK (unknown origin) expressed in baculovirus infected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-NH2 peptide as su...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM255274(US9481682, 23)

IC50: 0.110nMAssay Description:Inhibition of recombinant full length BTK (unknown origin) expressed in baculovirus infected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-NH2 peptide as su...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM255300(US9481682, 49)

IC50: 0.110nMAssay Description:Inhibition of recombinant full length BTK (unknown origin) expressed in baculovirus infected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-NH2 peptide as su...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM255303(US9481682, 52)

IC50: 0.120nMAssay Description:Inhibition of recombinant full length BTK (unknown origin) expressed in baculovirus infected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-NH2 peptide as su...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM255299(US9481682, 48)

IC50: 0.130nMAssay Description:Inhibition of recombinant full length BTK (unknown origin) expressed in baculovirus infected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-NH2 peptide as su...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM50558092(CHEMBL4784814)

IC50: 0.150nMAssay Description:Reversible inhibition of recombinant full length BTK (unknown origin) baculovirus infected Sf9 cells using biotinylated EQEDEPEGDYFEWLE-NH2 peptide a...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM255320(US9481682, 69)

IC50: 0.160nMAssay Description:Inhibition of recombinant full length BTK (unknown origin) expressed in baculovirus infected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-NH2 peptide as su...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM50558095(CHEMBL4752314)

IC50: 0.170nMAssay Description:Reversible inhibition of recombinant full length BTK (unknown origin) baculovirus infected Sf9 cells using biotinylated EQEDEPEGDYFEWLE-NH2 peptide a...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM267789(4-{8-amino-3-[(3R,6S)-1-(cyclopropylcarbonyl)-6-me...)

IC50: 0.170nMAssay Description:Reversible inhibition of recombinant full length BTK (unknown origin) baculovirus infected Sf9 cells using biotinylated EQEDEPEGDYFEWLE-NH2 peptide a...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM50558093(CHEMBL4798236)

IC50: 0.190nMAssay Description:Reversible inhibition of recombinant full length BTK (unknown origin) baculovirus infected Sf9 cells using biotinylated EQEDEPEGDYFEWLE-NH2 peptide a...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM288560(4-[8-amino-1-(4-{[4- (trifluoromethyl) pyridin-2- ...)

IC50: 0.200nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM50233392(CHEMBL4068131)

IC50: 0.200nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM288473((1S,3R)-3-[8-amino-1- (4-{[4- (trifluoromethyl) py...)

IC50: 0.200nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM50233389(CHEMBL4070865)

IC50: 0.200nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM255338(US9481682, 116 | US9481682, 88)

IC50: 0.210nMAssay Description:Inhibition of recombinant full length BTK (unknown origin) expressed in baculovirus infected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-NH2 peptide as su...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM50558088(CHEMBL4751655)

IC50: 0.220nMAssay Description:Reversible inhibition of recombinant full length BTK (unknown origin) baculovirus infected Sf9 cells using biotinylated EQEDEPEGDYFEWLE-NH2 peptide a...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM255357(US9481682, 107)

IC50: 0.260nMAssay Description:Inhibition of recombinant full length BTK (unknown origin) expressed in baculovirus infected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-NH2 peptide as su...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM50560329(CHEMBL4757041)

IC50: 0.260nMAssay Description:Inhibition of recombinant full length BTK (unknown origin) expressed in baculovirus infected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-NH2 peptide as su...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM267703((R)-4-(8-amino-5-deutero-3-(1-(3-methoxypropanoyl)...)

IC50: 0.270nMAssay Description:Reversible inhibition of recombinant full length BTK (unknown origin) baculovirus infected Sf9 cells using biotinylated EQEDEPEGDYFEWLE-NH2 peptide a...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM267791(4-{8-amino-3-[(3R,6S)-1-(cyclopropylcarbonyl)-6-me...)

IC50: 0.280nMAssay Description:Reversible inhibition of recombinant full length BTK (unknown origin) baculovirus infected Sf9 cells using biotinylated EQEDEPEGDYFEWLE-NH2 peptide a...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM267790(4-(8-amino-3-{(3R,6S)-6-methyl-1-[(3-methyloxetan-...)

IC50: 0.300nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM288564(4-[8-amino-1-(2- ethoxy-4-{[4- (trifluoromethyl) p...)

IC50: 0.300nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM50233391(CHEMBL4081444)

IC50: 0.300nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM50233388(CHEMBL4081452)

IC50: 0.300nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM50233386(CHEMBL4100424)

IC50: 0.300nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM267790(4-(8-amino-3-{(3R,6S)-6-methyl-1-[(3-methyloxetan-...)

IC50: 0.310nMAssay Description:Inhibition of recombinant full length BTK (unknown origin) expressed in baculovirus infected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-NH2 peptide as su...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM267819(4-(8-amino-3-{(3S,6S)-6-(methoxymethyl)-1-[(3-meth...)

IC50: 0.310nMAssay Description:Reversible inhibition of recombinant full length BTK (unknown origin) baculovirus infected Sf9 cells using biotinylated EQEDEPEGDYFEWLE-NH2 peptide a...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM267790(4-(8-amino-3-{(3R,6S)-6-methyl-1-[(3-methyloxetan-...)

IC50: 0.310nMAssay Description:Reversible inhibition of recombinant full length BTK (unknown origin) baculovirus infected Sf9 cells using biotinylated EQEDEPEGDYFEWLE-NH2 peptide a...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM50558112(CHEMBL4799627)

IC50: 0.320nMAssay Description:Reversible inhibition of recombinant full length BTK (unknown origin) baculovirus infected Sf9 cells using biotinylated EQEDEPEGDYFEWLE-NH2 peptide a...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM50558090(CHEMBL4756290)

IC50: 0.320nMAssay Description:Reversible inhibition of recombinant full length BTK (unknown origin) baculovirus infected Sf9 cells using biotinylated EQEDEPEGDYFEWLE-NH2 peptide a...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM267792(4-{8-amino-3-[(3R,6S)-6-methyl-1-propanoylpiperidi...)

IC50: 0.360nMAssay Description:Reversible inhibition of recombinant full length BTK (unknown origin) baculovirus infected Sf9 cells using biotinylated EQEDEPEGDYFEWLE-NH2 peptide a...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM267869(4-(8-amino-3-{(3R)-1-[(3-methyloxetan-3-yl)carbony...)

IC50: 0.370nMAssay Description:Reversible inhibition of recombinant full length BTK (unknown origin) baculovirus infected Sf9 cells using biotinylated EQEDEPEGDYFEWLE-NH2 peptide a...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM50233393(CHEMBL4096195)

IC50: 0.400nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM288429(3-[8-amino-1-(4-{[4- (trifluoromethyl) pyridin-2- ...)

IC50: 0.400nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM288308(US10087188, Example 1 | US10087188, Example 6)

IC50: 0.400nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM288492((1R,2R,5R)-5-[8- amino-1-(4-{[4- (trifluoromethyl)...)

IC50: 0.400nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM50558097(CHEMBL4787427)

IC50: 0.410nMAssay Description:Reversible inhibition of recombinant full length BTK (unknown origin) baculovirus infected Sf9 cells using biotinylated EQEDEPEGDYFEWLE-NH2 peptide a...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM50558109(CHEMBL4764215)

IC50: 0.410nMAssay Description:Reversible inhibition of recombinant full length BTK (unknown origin) baculovirus infected Sf9 cells using biotinylated EQEDEPEGDYFEWLE-NH2 peptide a...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM50558107(CHEMBL4743911)

IC50: 0.420nMAssay Description:Reversible inhibition of recombinant full length BTK (unknown origin) baculovirus infected Sf9 cells using biotinylated EQEDEPEGDYFEWLE-NH2 peptide a...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM50558094(CHEMBL4764139)

IC50: 0.450nMAssay Description:Reversible inhibition of recombinant full length BTK (unknown origin) baculovirus infected Sf9 cells using biotinylated EQEDEPEGDYFEWLE-NH2 peptide a...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM255322(US9481682, 71)

IC50: 0.480nMAssay Description:Inhibition of recombinant full length BTK (unknown origin) expressed in baculovirus infected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-NH2 peptide as su...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM50233385(CHEMBL4062247)

IC50: 0.5nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM288550(US10087188, Example 158 | cis-4-[8-amino-1-(4- {[4...)

IC50: 0.5nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM50233396(CHEMBL4059483)

IC50: 0.5nMAssay Description:Inhibition of 6-His-tagged recombinant full length BTK (unknown origin) expressed in baculovirus-transfected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-N...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL

PNG

BDBM267870(4-(8-amino-3-{(3R)-1-[(3-methyloxetan-3-yl)carbony...)

IC50: 0.520nMAssay Description:Reversible inhibition of recombinant full length BTK (unknown origin) baculovirus infected Sf9 cells using biotinylated EQEDEPEGDYFEWLE-NH2 peptide a...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Displayed 1 to 50 (of 362 total ) | Next | Last >>

Filter my 362 hits

Targets 21▿
- Tyrosine-protein kinase BTK 202
- Interleukin-1 receptor-associated kinase 4 23
- Tyrosine-protein kinase Lck 8
- Cytoplasmic tyrosine-protein kinase BMX 8
- Tyrosine-protein kinase Tec 8
- Protein-tyrosine kinase 6 8
- Tyrosine-protein kinase TXK 8
- Tyrosine-protein kinase Blk 8
- Tyrosine-protein kinase Lyn 8
- Receptor tyrosine-protein kinase erbB-4 8
- Tyrosine-protein kinase FRK 8
- Tyrosine-protein kinase Srms 8
- Tyrosine-protein kinase Yes 7
- Proto-oncogene tyrosine-protein kinase Src 7
- Tyrosine-protein kinase Fyn 7
- Tyrosine-protein kinase CSK 7
- Voltage-dependent L-type calcium channel subunit alpha-1C 7
- Potassium voltage-gated channel subfamily H member 2 7
- Sodium channel protein type 5 subunit alpha 7
- Tyrosine-protein kinase Fgr 6
- Tyrosine-protein kinase ITK/TSK 2
- ...
Publications 4▿
- Bioorg Med Chem Lett 30: (2020) 143
- ACS Med Chem Lett 7: 198-203 (2016) 115
- Bioorg Med Chem Lett 27: 1471-1477 (2017) 81
- Bioorg Med Chem Lett 27: 2721-2726 (2017) 23
Institutions 3▿
- Merck 224
- Merck Research Laboratories 115
- Astrazeneca 23
Affinity: 0.083 to 6.0E+4 nM▿
- IC50 360
- EC50 2
- Affinity ≤ nM
Xtal structures: 6
Docked structures: 0
Catalog Cmpds: 2