Affinity DataKi: 0.00480nMAssay Description:Inhibition of Human cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 0.00990nM ΔG°: -62.2kJ/molepH: 5.5 T: 2°CAssay Description:Potential inhibitors were evaluated using the progress curve method. Assays were carried out in the presence of variable concentrations of test compo...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: <0.0200nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: <0.0200nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: <0.0200nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: <0.0200nMAssay Description:Inhibition of N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells assessed as inhibition...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: <0.0200nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: <0.0200nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: <0.0200nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: <0.0200nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: <0.0200nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: <0.0200nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: <0.0200nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: <0.0200nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: <0.0200nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.0200nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: <0.0200nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: <0.0200nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: <0.0200nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: <0.0200nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.0220nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.0230nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.0250nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.0280nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.0280nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.0280nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.0290nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.0290nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Vanderbilt University School Of Medicine
Curated by ChEMBL
Vanderbilt University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 0.0300nMAssay Description:Inhibition of FITC-labeled Bak peptide binding to MBP-fused Mcl-1 (unknown origin) measured after 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Vanderbilt University School Of Medicine
Curated by ChEMBL
Vanderbilt University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 0.0300nMAssay Description:Inhibition of FITC-labeled Bak peptide binding to MBP-fused Mcl-1 (unknown origin) measured after 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Vanderbilt University School Of Medicine
Curated by ChEMBL
Vanderbilt University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 0.0300nMAssay Description:Inhibition of FITC-labeled Bak peptide binding to MBP-fused Mcl-1 (unknown origin) measured after 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.0330nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.0350nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.0360nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.0390nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
Affinity DataKi: 0.0400nM ΔG°: -58.8kJ/molepH: 5.5 T: 2°CAssay Description:Potential inhibitors were evaluated using the progress curve method. Assays were carried out in the presence of variable concentrations of test compo...More data for this Ligand-Target Pair
Affinity DataKi: 0.0410nM ΔG°: -58.7kJ/molepH: 5.5 T: 2°CAssay Description:Potential inhibitors were evaluated using the progress curve method. Assays were carried out in the presence of variable concentrations of test compo...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.0440nMAssay Description:Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.0460nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.0550nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
Affinity DataKi: 0.0630nMAssay Description:Potential inhibitors were evaluated using the progress curve method. Assays were carried out in the presence of variable concentrations of test compo...More data for this Ligand-Target Pair
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Frederick National Laboratory For Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.0640nMAssay Description:Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells asse...More data for this Ligand-Target Pair
Affinity DataKi: 0.0680nM ΔG°: -57.4kJ/molepH: 5.5 T: 2°CAssay Description:Potential inhibitors were evaluated using the progress curve method. Assays were carried out in the presence of variable concentrations of test compo...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Vanderbilt University School Of Medicine
Curated by ChEMBL
Vanderbilt University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 0.0810nMAssay Description:Inhibition of FITC-labeled Bak peptide binding to MBP-fused Mcl-1 (unknown origin) measured after 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Vanderbilt University School Of Medicine
Curated by ChEMBL
Vanderbilt University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 0.0890nMAssay Description:Inhibition of FITC-Bak-BH3 binding to MBP-fused MCL1 (172 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 CodonPlus (DE3) RIL af...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Vanderbilt University School Of Medicine
Curated by ChEMBL
Vanderbilt University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 0.0890nMAssay Description:Inhibition of FITC-Bak-BH3 binding to MBP-fused MCL1 (172 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 CodonPlus (DE3) RIL af...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Vanderbilt University School Of Medicine
Curated by ChEMBL
Vanderbilt University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 0.0890nMAssay Description:Inhibition of FITC-Bak-BH3 binding to MBP-fused MCL1 (172 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 CodonPlus (DE3) RIL af...More data for this Ligand-Target Pair
Affinity DataKi: 0.140nM ΔG°: -55.7kJ/molepH: 5.5 T: 2°CAssay Description:Potential inhibitors were evaluated using the progress curve method. Assays were carried out in the presence of variable concentrations of test compo...More data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Inhibition of Human cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nM ΔG°: -55.3kJ/molepH: 5.5 T: 2°CAssay Description:Potential inhibitors were evaluated using the progress curve method. Assays were carried out in the presence of variable concentrations of test compo...More data for this Ligand-Target Pair