Affinity DataIC50: 0.300nMAssay Description:Recombinant human DPP1 enzyme (R&D Systems, Cat. No. 1071-CY) at a final concentration of 100 μg/mL was mixed with recombinant human cathepsin L...More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Recombinant human DPP1 enzyme (R&D Systems, Cat. No. 1071-CY) at a final concentration of 100 μg/mL was mixed with recombinant human cathepsin L...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of CCL3 induced chemotaxis in human T lymphocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Recombinant human DPP1 enzyme (R&D Systems, Cat. No. 1071-CY) at a final concentration of 100 μg/mL was mixed with recombinant human cathepsin L...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of CCL3 induced chemotaxis in human T lymphocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Recombinant human DPP1 enzyme (R&D Systems, Cat. No. 1071-CY) at a final concentration of 100 μg/mL was mixed with recombinant human cathepsin L...More data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Recombinant human DPP1 enzyme (R&D Systems, Cat. No. 1071-CY) at a final concentration of 100 μg/mL was mixed with recombinant human cathepsin L...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of CCL3 induced chemotaxis in human T lymphocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 6.70nMAssay Description:Recombinant human DPP1 enzyme (R&D Systems, Cat. No. 1071-CY) at a final concentration of 100 μg/mL was mixed with recombinant human cathepsin L...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of CCL3 induced chemotaxis in human T lymphocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of CCL3 binding to C-C chemokine receptor type 1More data for this Ligand-Target Pair
Affinity DataIC50: 7.40nMAssay Description:Recombinant human DPP1 enzyme (R&D Systems, Cat. No. 1071-CY) at a final concentration of 100 μg/mL was mixed with recombinant human cathepsin L...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of CCL3 induced chemotaxis in human T lymphocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of CCL3 binding to C-C chemokine receptor type 1More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of CCL3 binding to C-C chemokine receptor type 1More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of CCL3 binding to C-C chemokine receptor type 1More data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
Sun Yat-Sen University
Curated by ChEMBL
Sun Yat-Sen University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of PDE8A1 (480 to 820 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]-cAMP substrate incubated for 15 mins by liq...More data for this Ligand-Target Pair
Affinity DataIC50: 12.9nMAssay Description:Recombinant human DPP1 enzyme (R&D Systems, Cat. No. 1071-CY) at a final concentration of 100 μg/mL was mixed with recombinant human cathepsin L...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of CCL3 induced chemotaxis in human T lymphocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of CCL3 binding to C-C chemokine receptor type 1More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of pentamer formation of GST-tagged HPV16 major capsid protein L1 assessed as increased L1-m peak formation incubated with compound after ...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of CCL3 binding to C-C chemokine receptor type 1More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Recombinant human DPP1 enzyme (R&D Systems, Cat. No. 1071-CY) at a final concentration of 100 μg/mL was mixed with recombinant human cathepsin L...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of CCL3 binding to C-C chemokine receptor type 1More data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
Sun Yat-Sen University
Curated by ChEMBL
Sun Yat-Sen University
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of PDE8A1 (480 to 820 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]-cAMP substrate incubated for 15 mins by liq...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of CCL3 binding to C-C chemokine receptor type 1More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of CCL3 binding to C-C chemokine receptor type 1More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of CCL3 binding to C-C chemokine receptor type 1More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of CCL3 binding to C-C chemokine receptor type 1More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of CCL3 induced chemotaxis in human T lymphocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Recombinant human DPP1 enzyme (R&D Systems, Cat. No. 1071-CY) at a final concentration of 100 μg/mL was mixed with recombinant human cathepsin L...More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibitory activity of compound against renin was determinedMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
Sun Yat-Sen University
Curated by ChEMBL
Sun Yat-Sen University
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of PDE8A1 (480 to 820 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]-cAMP substrate incubated for 15 mins by liq...More data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of CCL3 binding to C-C chemokine receptor type 1More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of pentamer formation of GST-tagged HPV16 major capsid protein L1 assessed as increased L1-m peak formation incubated with compound after ...More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of CCL3 binding to C-C chemokine receptor type 1More data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of CCL3 binding to C-C chemokine receptor type 1More data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Inhibition of CCL3 binding to C-C chemokine receptor type 1More data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of CCL3 induced chemotaxis in human T lymphocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Inhibition of CCL3 induced chemotaxis in human T lymphocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Recombinant human DPP1 enzyme (R&D Systems, Cat. No. 1071-CY) at a final concentration of 100 μg/mL was mixed with recombinant human cathepsin L...More data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Inhibition of CCL3 binding to C-C chemokine receptor type 1More data for this Ligand-Target Pair
TargetP2Y purinoceptor 12(Homo sapiens (Human))
King Abdullah International Medical Research Center/King Saud Bin Abdulaziz University For Health Sciences
Curated by ChEMBL
King Abdullah International Medical Research Center/King Saud Bin Abdulaziz University For Health Sciences
Curated by ChEMBL
Affinity DataIC50: 86nMAssay Description:Displacement of [3H]2MeSADP from P2Y12 receptor in human platelets after 60 mins by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of CCL3 induced chemotaxis in human T lymphocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of CCL3 induced chemotaxis in human T lymphocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of CCL3 binding to C-C chemokine receptor type 1More data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
Sun Yat-Sen University
Curated by ChEMBL
Sun Yat-Sen University
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of PDE8A1 (480 to 820 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]-cAMP substrate incubated for 15 mins by liq...More data for this Ligand-Target Pair
TargetP2Y purinoceptor 12(Homo sapiens (Human))
King Abdullah International Medical Research Center/King Saud Bin Abdulaziz University For Health Sciences
Curated by ChEMBL
King Abdullah International Medical Research Center/King Saud Bin Abdulaziz University For Health Sciences
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Displacement of [3H]2MeSADP from P2Y12 receptor in human platelets after 60 mins by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of CCL3 binding to C-C chemokine receptor type 1More data for this Ligand-Target Pair
TargetP2Y purinoceptor 12(Homo sapiens (Human))
King Abdullah International Medical Research Center/King Saud Bin Abdulaziz University For Health Sciences
Curated by ChEMBL
King Abdullah International Medical Research Center/King Saud Bin Abdulaziz University For Health Sciences
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Displacement of [3H]2MeSADP from P2Y12 receptor in human platelets after 60 mins by TopCount scintillation counting methodMore data for this Ligand-Target Pair