Affinity DataIC50: 1.20nMAssay Description:Inhibition of [3H]R5020 binding to cytosolic progesterone receptor (PRc) of rat uterusMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of [3H]R5020 binding to cytosolic progesterone receptor (PRc) of rat uterusMore data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Inhibition of [3H]R5020 binding to cytosolic progesterone receptor (PRc) of rat uterusMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of [3H]R5020 binding to cytosolic progesterone receptor (PRc) of rat uterusMore data for this Ligand-Target Pair
TargetLethal(3)malignant brain tumor-like protein 3(Homo sapiens (Human))
University Of North Carolina
Curated by ChEMBL
University Of North Carolina
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of His-tagged L3MBTL3 (unknown origin) using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under ...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of full length PARP1 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in ADP-ribosyl transferase activity u...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of full length PARP1 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in ADP-ribosyl transferase activity u...More data for this Ligand-Target Pair
TargetLethal(3)malignant brain tumor-like protein 3(Homo sapiens (Human))
University Of North Carolina
Curated by ChEMBL
University Of North Carolina
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of His-tagged L3MBTL3 (unknown origin) using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under ...More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of full length PARP1 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in ADP-ribosyl transferase activity u...More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of full length PARP1 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in ADP-ribosyl transferase activity u...More data for this Ligand-Target Pair
TargetLethal(3)malignant brain tumor-like protein 3(Homo sapiens (Human))
University Of North Carolina
Curated by ChEMBL
University Of North Carolina
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of His-tagged L3MBTL3 (unknown origin) using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under ...More data for this Ligand-Target Pair
TargetLethal(3)malignant brain tumor-like protein 3(Homo sapiens (Human))
University Of North Carolina
Curated by ChEMBL
University Of North Carolina
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Inhibition of His-tagged L3MBTL3 (unknown origin) using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under ...More data for this Ligand-Target Pair
TargetLethal(3)malignant brain tumor-like protein 3(Homo sapiens (Human))
University Of North Carolina
Curated by ChEMBL
University Of North Carolina
Curated by ChEMBL
Affinity DataIC50: 62nMAssay Description:Inhibition of His-tagged L3MBTL3 (unknown origin) using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under ...More data for this Ligand-Target Pair
TargetLethal(3)malignant brain tumor-like protein 3(Homo sapiens (Human))
University Of North Carolina
Curated by ChEMBL
University Of North Carolina
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of His-tagged L3MBTL3 (unknown origin) using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under ...More data for this Ligand-Target Pair
TargetLethal(3)malignant brain tumor-like protein 3(Homo sapiens (Human))
University Of North Carolina
Curated by ChEMBL
University Of North Carolina
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of His-tagged L3MBTL3 (unknown origin) using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under ...More data for this Ligand-Target Pair
TargetLethal(3)malignant brain tumor-like protein 3(Homo sapiens (Human))
University Of North Carolina
Curated by ChEMBL
University Of North Carolina
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of His-tagged L3MBTL3 (unknown origin) using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under ...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of full length PARP1 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in ADP-ribosyl transferase activity u...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of full length PARP1 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in ADP-ribosyl transferase activity u...More data for this Ligand-Target Pair
TargetLethal(3)malignant brain tumor-like protein 3(Homo sapiens (Human))
University Of North Carolina
Curated by ChEMBL
University Of North Carolina
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of His-tagged L3MBTL3 (unknown origin) using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under ...More data for this Ligand-Target Pair
TargetLethal(3)malignant brain tumor-like protein 3(Homo sapiens (Human))
University Of North Carolina
Curated by ChEMBL
University Of North Carolina
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of His-tagged L3MBTL3 (unknown origin) using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under ...More data for this Ligand-Target Pair
Affinity DataIC50: 195nMAssay Description:Inhibition of full length PARP1 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in ADP-ribosyl transferase activity u...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of full length PARP1 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in ADP-ribosyl transferase activity u...More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of full length PARP1 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in ADP-ribosyl transferase activity u...More data for this Ligand-Target Pair
Affinity DataIC50: 224nMAssay Description:Inhibition of full length PARP1 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in ADP-ribosyl transferase activity u...More data for this Ligand-Target Pair
Affinity DataIC50: 245nMAssay Description:Inhibition of hexa-histidine tagged recombinant tankyrase 1 biotinylated catalytic domain (amino acids 1106 to 1325) (unknown origin) expressed in Es...More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of hexa-histidine tagged recombinant tankyrase 1 biotinylated catalytic domain (amino acids 1106 to 1325) (unknown origin) expressed in Es...More data for this Ligand-Target Pair
Affinity DataIC50: 257nMAssay Description:Inhibition of full length PARP1 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in ADP-ribosyl transferase activity u...More data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of full length PARP1 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in ADP-ribosyl transferase activity u...More data for this Ligand-Target Pair
TargetLethal(3)malignant brain tumor-like protein 3(Homo sapiens (Human))
University Of North Carolina
Curated by ChEMBL
University Of North Carolina
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of His-tagged L3MBTL3 (unknown origin) using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under ...More data for this Ligand-Target Pair
Affinity DataIC50: 288nMAssay Description:Inhibition of hexa-histidine tagged recombinant tankyrase 1 biotinylated catalytic domain (amino acids 1106 to 1325) (unknown origin) expressed in Es...More data for this Ligand-Target Pair
Affinity DataIC50: 288nMAssay Description:Inhibition of hexa-histidine tagged recombinant tankyrase 1 biotinylated catalytic domain (amino acids 1106 to 1325) (unknown origin) expressed in Es...More data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of hexa-histidine tagged recombinant tankyrase 1 biotinylated catalytic domain (amino acids 1106 to 1325) (unknown origin) expressed in Es...More data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of hexa-histidine tagged recombinant tankyrase 1 biotinylated catalytic domain (amino acids 1106 to 1325) (unknown origin) expressed in Es...More data for this Ligand-Target Pair
TargetLethal(3)malignant brain tumor-like protein 3(Homo sapiens (Human))
University Of North Carolina
Curated by ChEMBL
University Of North Carolina
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of His-tagged L3MBTL3 (unknown origin) using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under ...More data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Inhibition of hexa-histidine tagged recombinant tankyrase 1 biotinylated catalytic domain (amino acids 1106 to 1325) (unknown origin) expressed in Es...More data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Inhibition of tankyrase 2 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in ADP-ribosyl transferase...More data for this Ligand-Target Pair
Affinity DataIC50: 331nMAssay Description:Inhibition of hexa-histidine tagged recombinant tankyrase 1 biotinylated catalytic domain (amino acids 1106 to 1325) (unknown origin) expressed in Es...More data for this Ligand-Target Pair
Affinity DataIC50: 331nMAssay Description:Inhibition of tankyrase 2 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in ADP-ribosyl transferase...More data for this Ligand-Target Pair
Affinity DataIC50: 347nMAssay Description:Inhibition of hexa-histidine tagged recombinant tankyrase 1 biotinylated catalytic domain (amino acids 1106 to 1325) (unknown origin) expressed in Es...More data for this Ligand-Target Pair
TargetLethal(3)malignant brain tumor-like protein 3(Homo sapiens (Human))
University Of North Carolina
Curated by ChEMBL
University Of North Carolina
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of His-tagged L3MBTL3 (unknown origin) using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under ...More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of hexa-histidine tagged recombinant tankyrase 1 biotinylated catalytic domain (amino acids 1106 to 1325) (unknown origin) expressed in Es...More data for this Ligand-Target Pair
TargetLethal(3)malignant brain tumor-like protein 3(Homo sapiens (Human))
University Of North Carolina
Curated by ChEMBL
University Of North Carolina
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of His-tagged L3MBTL3 (unknown origin) using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under ...More data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibition of hexa-histidine tagged recombinant tankyrase 1 biotinylated catalytic domain (amino acids 1106 to 1325) (unknown origin) expressed in Es...More data for this Ligand-Target Pair
Affinity DataIC50: 372nMAssay Description:Inhibition of hexa-histidine tagged recombinant tankyrase 1 biotinylated catalytic domain (amino acids 1106 to 1325) (unknown origin) expressed in Es...More data for this Ligand-Target Pair
TargetLethal(3)malignant brain tumor-like protein 3(Homo sapiens (Human))
University Of North Carolina
Curated by ChEMBL
University Of North Carolina
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of His-tagged L3MBTL3 (unknown origin) using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under ...More data for this Ligand-Target Pair
Affinity DataIC50: 468nMAssay Description:Inhibition of tankyrase 2 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in ADP-ribosyl transferase...More data for this Ligand-Target Pair
Affinity DataIC50: 470nMAssay Description:Inhibition of tankyrase 2 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in ADP-ribosyl transferase...More data for this Ligand-Target Pair
Affinity DataIC50: 570nMAssay Description:Inhibition of hexa-histidine tagged recombinant tankyrase 1 biotinylated catalytic domain (amino acids 1106 to 1325) (unknown origin) expressed in Es...More data for this Ligand-Target Pair
Affinity DataIC50: 575nMAssay Description:Inhibition of hexa-histidine tagged recombinant tankyrase 1 biotinylated catalytic domain (amino acids 1106 to 1325) (unknown origin) expressed in Es...More data for this Ligand-Target Pair
TargetLethal(3)malignant brain tumor-like protein 3(Homo sapiens (Human))
University Of North Carolina
Curated by ChEMBL
University Of North Carolina
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Inhibition of His-tagged L3MBTL3 (unknown origin) using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under ...More data for this Ligand-Target Pair