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Found 160 with Last Name = 'zhou' and Initial = 'ne'
TargetAdenosine kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM50524390(CHEMBL4475619)
Affinity DataKi:  5.30nMAssay Description:Inhibition of wild-type N-terminal TEV cleavage site-fused/His-tagged Mycobacterium tuberculosis H37Rv adenosine kinase expressed in Escherichia coli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM50524393(CHEMBL4448092)
Affinity DataKi:  16nMAssay Description:Inhibition of wild-type N-terminal TEV cleavage site-fused/His-tagged Mycobacterium tuberculosis H37Rv adenosine kinase expressed in Escherichia coli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM50524387(CHEMBL4566815)
Affinity DataKi:  19nMAssay Description:Inhibition of wild-type N-terminal TEV cleavage site-fused/His-tagged Mycobacterium tuberculosis H37Rv adenosine kinase expressed in Escherichia coli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM50524392(CHEMBL4475059)
Affinity DataKi:  19nMAssay Description:Inhibition of wild-type N-terminal TEV cleavage site-fused/His-tagged Mycobacterium tuberculosis H37Rv adenosine kinase expressed in Escherichia coli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM50524388(CHEMBL4449169)
Affinity DataKi:  20nMAssay Description:Inhibition of wild-type N-terminal TEV cleavage site-fused/His-tagged Mycobacterium tuberculosis H37Rv adenosine kinase expressed in Escherichia coli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM50524389(CHEMBL4525944)
Affinity DataKi:  21nMAssay Description:Inhibition of wild-type N-terminal TEV cleavage site-fused/His-tagged Mycobacterium tuberculosis H37Rv adenosine kinase expressed in Escherichia coli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM50524394(CHEMBL4539148)
Affinity DataKi:  23nMAssay Description:Inhibition of wild-type N-terminal TEV cleavage site-fused/His-tagged Mycobacterium tuberculosis H37Rv adenosine kinase expressed in Escherichia coli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM50524383(CHEMBL4442160)
Affinity DataKi:  26nMAssay Description:Inhibition of wild-type N-terminal TEV cleavage site-fused/His-tagged Mycobacterium tuberculosis H37Rv adenosine kinase expressed in Escherichia coli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM50524384(CHEMBL4458246)
Affinity DataKi:  28nMAssay Description:Inhibition of wild-type N-terminal TEV cleavage site-fused/His-tagged Mycobacterium tuberculosis H37Rv adenosine kinase expressed in Escherichia coli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Homo sapiens (Human))
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM50375654(CHEMBL99203 | US11633415, Compound 5-iodotubercidi...)
Affinity DataKi:  30nMAssay Description:Inhibition of purified human adenosine kinase using varying levels of [3H]Ado as substrate in presence of adenosine deaminase inhibitor deoxycoformyc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM50524385(CHEMBL4463459)
Affinity DataKi:  33nMAssay Description:Inhibition of wild-type N-terminal TEV cleavage site-fused/His-tagged Mycobacterium tuberculosis H37Rv adenosine kinase expressed in Escherichia coli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM50524386(CHEMBL4474951)
Affinity DataKi:  48nMAssay Description:Inhibition of wild-type N-terminal TEV cleavage site-fused/His-tagged Mycobacterium tuberculosis H37Rv adenosine kinase expressed in Escherichia coli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAdenosine kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM50524391(CHEMBL2042164)
Affinity DataKi:  120nMAssay Description:Inhibition of wild-type N-terminal TEV cleavage site-fused/His-tagged Mycobacterium tuberculosis H37Rv adenosine kinase expressed in Escherichia coli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAdenosine kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM50375654(CHEMBL99203 | US11633415, Compound 5-iodotubercidi...)
Affinity DataKi:  210nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Ra ATCC 25177 adenosine kinase using varying levels of [3H]Ado as substrate in presence of adenosine deam...More data for this Ligand-Target Pair
TargetAdenosine kinase(Homo sapiens (Human))
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM50524383(CHEMBL4442160)
Affinity DataKi:  410nMAssay Description:Inhibition of recombinant human adenosine kinase expressed in Escherichia coli BL21 (DE3) using adenosine as substrate in presence of ATP and PEP by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Homo sapiens (Human))
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM50524385(CHEMBL4463459)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of recombinant human adenosine kinase expressed in Escherichia coli BL21 (DE3) using adenosine as substrate in presence of ATP and PEP by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Homo sapiens (Human))
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM50524391(CHEMBL2042164)
Affinity DataKi:  5.10E+3nMAssay Description:Inhibition of recombinant human adenosine kinase expressed in Escherichia coli BL21 (DE3) using adenosine as substrate in presence of ATP and PEP by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Homo sapiens (Human))
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM50524390(CHEMBL4475619)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of recombinant human adenosine kinase expressed in Escherichia coli BL21 (DE3) using adenosine as substrate in presence of ATP and PEP by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Homo sapiens (Human))
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM50524387(CHEMBL4566815)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of recombinant human adenosine kinase expressed in Escherichia coli BL21 (DE3) using adenosine as substrate in presence of ATP and PEP by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Homo sapiens (Human))
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM50524393(CHEMBL4448092)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of recombinant human adenosine kinase expressed in Escherichia coli BL21 (DE3) using adenosine as substrate in presence of ATP and PEP by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Homo sapiens (Human))
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM50524389(CHEMBL4525944)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of recombinant human adenosine kinase expressed in Escherichia coli BL21 (DE3) using adenosine as substrate in presence of ATP and PEP by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Homo sapiens (Human))
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM50524388(CHEMBL4449169)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of recombinant human adenosine kinase expressed in Escherichia coli BL21 (DE3) using adenosine as substrate in presence of ATP and PEP by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Homo sapiens (Human))
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM50524392(CHEMBL4475059)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of recombinant human adenosine kinase expressed in Escherichia coli BL21 (DE3) using adenosine as substrate in presence of ATP and PEP by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Homo sapiens (Human))
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM50524386(CHEMBL4474951)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of recombinant human adenosine kinase expressed in Escherichia coli BL21 (DE3) using adenosine as substrate in presence of ATP and PEP by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Homo sapiens (Human))
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM50524384(CHEMBL4458246)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of recombinant human adenosine kinase expressed in Escherichia coli BL21 (DE3) using adenosine as substrate in presence of ATP and PEP by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121904(CHEMBL30401 | [(S)-1-((3S,4R)-2-Oxo-4-phenoxy-azet...)
Affinity DataIC50: <0.100nMAssay Description:Inhibition of recombinant human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121907(CHEMBL31788 | [(S)-1-((3R,4S)-2-Oxo-4-phenylsulfan...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of recombinant human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121902(CHEMBL287630 | [(S)-1-((2S,3R)-2-Benzenesulfonyl-4...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of recombinant human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121041(CHEMBL326093 | [(S)-1-((R)-4,7-Dioxo-4-(S)-oxo-4la...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin K cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121039(CHEMBL114410 | [(S)-2-Cyclohexyl-1-((5S,6R)-4,4,7-...)
Affinity DataIC50:  0.700nMAssay Description:In vitro Inhibitory activity of the compound was determined against Cathepsin S cysteine protease by using Cbz-Val-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Rattus norvegicus)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121039(CHEMBL114410 | [(S)-2-Cyclohexyl-1-((5S,6R)-4,4,7-...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin L cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Rattus norvegicus)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121041(CHEMBL326093 | [(S)-1-((R)-4,7-Dioxo-4-(S)-oxo-4la...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin L cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Rattus norvegicus)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121040(CHEMBL117928 | [(S)-2-Pyridin-3-yl-1-((5S,6R)-4,4,...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin L cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121038(CHEMBL113706 | [(S)-2-Thiophen-2-yl-1-((5S,6R)-4,4...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin K cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121040(CHEMBL117928 | [(S)-2-Pyridin-3-yl-1-((5S,6R)-4,4,...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin K cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121904(CHEMBL30401 | [(S)-1-((3S,4R)-2-Oxo-4-phenoxy-azet...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of recombinant human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Rattus norvegicus)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121038(CHEMBL113706 | [(S)-2-Thiophen-2-yl-1-((5S,6R)-4,4...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin L cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Rattus norvegicus)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121044(CHEMBL116041 | [(S)-2-(3-Fluoro-phenyl)-1-((5S,6R)...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin L cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121042(CHEMBL323638 | [(S)-2-Naphthalen-2-yl-1-((5S,6R)-4...)
Affinity DataIC50:  3nMAssay Description:In vitro Inhibitory activity of the compound was determined against Cathepsin S cysteine protease by using Cbz-Val-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Rattus norvegicus)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121042(CHEMBL323638 | [(S)-2-Naphthalen-2-yl-1-((5S,6R)-4...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin L cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Rattus norvegicus)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121030(CHEMBL115734 | [(S)-1-((5S,6S)-7-Oxo-4-oxa-1-aza-b...)
Affinity DataIC50:  4nMAssay Description:In vitro Inhibitory activity of the compound was determined against Cathepsin L cysteine protease by using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121038(CHEMBL113706 | [(S)-2-Thiophen-2-yl-1-((5S,6R)-4,4...)
Affinity DataIC50:  4.60nMAssay Description:In vitro Inhibitory activity of the compound was determined against Cathepsin S cysteine protease by using Cbz-Val-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121030(CHEMBL115734 | [(S)-1-((5S,6S)-7-Oxo-4-oxa-1-aza-b...)
Affinity DataIC50:  5nMAssay Description:In vitro Inhibitory activity of the compound was determined against Cathepsin K cysteine protease by using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121034(CHEMBL332025 | [1-((S)-7-Oxo-4-oxa-1-aza-bicyclo[3...)
Affinity DataIC50:  5nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin K cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121044(CHEMBL116041 | [(S)-2-(3-Fluoro-phenyl)-1-((5S,6R)...)
Affinity DataIC50:  6nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin K cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121902(CHEMBL287630 | [(S)-1-((2S,3R)-2-Benzenesulfonyl-4...)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121043(CHEMBL323637 | [(S)-1-((R)-4,7-Dioxo-4-(R)-oxo-4la...)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin K cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121039(CHEMBL114410 | [(S)-2-Cyclohexyl-1-((5S,6R)-4,4,7-...)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin K cysteine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121044(CHEMBL116041 | [(S)-2-(3-Fluoro-phenyl)-1-((5S,6R)...)
Affinity DataIC50:  8nMAssay Description:In vitro Inhibitory activity of the compound was determined against Cathepsin S cysteine protease by using Cbz-Val-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121907(CHEMBL31788 | [(S)-1-((3R,4S)-2-Oxo-4-phenylsulfan...)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of recombinant human Cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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